Key functions of thiamine Energy Metabolism: Converts carbohydrates into usable energy ATP for cells, powering the brain, muscles, and organs. Nervous System Support: Conducts nerve signals, synthesizes neurotransmitters, and maintains the myelin sheath, vital for cognitive function, memory, and mood.

Article:

https://richardgoldberg.substack.com/p/the-health-benefits-of-vitamin-b1

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PRIME MICROBIOME

Aab03-002

168 Chemicals Found in Food Disrupt Healthy Gut Microbe Growth

Quote:

Indra Roux, Ph.D., a member of the universitys MRC Toxicology Unit and the studys first author, said: Weve found that many chemicals designed to act only on one type of target, say insects or fungi, also affect gut bacteria. We were surprised that some of these chemicals had such strong effects. For example, many industrial chemicals like flame retardants and plasticizers that we are regularly in contact with werent thought to affect living organisms at all, but they do.

Article:

https://principia-scientific.com/168-chemicals-found-in-food-disrupt-healthy-gut-microbe-growth/

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PRIME CULTURE LANGUAGE

Aab03-005

When Words Dont Work: Losing Our Common Tongue

Quote:

What was revealing was not that a young viewer disliked Archie. That is understandable, though kind of sad. What was revealing was the absence of interpretation altogether. There was no recognition of satire, no sense that a character might exist to be examined rather than endorsed, no allowance for moral tension or narrative distance. The response bypassed understanding and went straight to judgment, and from judgment to punishment. The same loss of interpretive charity now shapes how we read our own moral history, at least for most people younger than Generation X.

Article:

https://pjmedia.com/jamie-wilson/2026/01/20/when-words-dont-work-losing-our-common-tongue-n4948523

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PRIME BRAIN PRACTICE

Aac03-001

Hidden Brain Injury behind Jordan Peterson -- Valium

Quote:

Benzodiasophene, VALIUM

Article:

https://youtube.com/watch?v=_q44phEpFjA

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PRIME POLLUTION

Aac03-002

A New Study Suggests That the Hysteria Over Microplastics May Be Overblown

Quote:

One of the scientists challenging the study was more blunt. The brain microplastic paper is a joke, said Dr Duan Materi#263;, at the Helmholtz Centre for Environmental Research in Germany. Fat is known to make false-positives for polyethylene. The brain has approximately 60 fat. ... Theres nothing unusual about this at all. This is the sausage-making part of science. Ideas and theories are constantly questioned and challenged by other scientists; new data is added to the mix, changing minds or hardening positions until a rough consensus is achieved.

Comment:

The dominant nanoparticles, and I mean VASTLY dominant nanoparticles that we are exposed to on a daily basis, are silicates from rocks. These are the inorganic portions of what we call soil, dirt, etc. We are also exposed to a wide variety of other natural nanoparticles from wood, wool, cotton, etc. Is anyone ressearching the effects of those nanoparticles? I am reminded of Dr. Ames, who developed the test for mutagenicity of our modern chemicals. There was qhite an alarm that set off. He later started testing natural foods we eat, and found them far more mutagenic. of course, as those plants are battling insects trying to eat them. We call many of those chemicals flavor, and seem to do ok with them.

Article:

https://pjmedia.com/rick-moran/2026/01/18/a-new-study-suggests-that-the-hysteria-over-microplastics-may-be-overblown-n4948438

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PRIME CULTURE POLITICS WAR-CONFL

Aac03-003

SHOCK CONFESSION: Mexican President Admits That Mass Migration Is a Tool to Reclaim and Conquer Americas Southwest

Quote:

Radical leftist former Mexican President Andrs Manuel Lpez Obrador, commonly known as AMLO, and his protege and current Mexican President Claudia Sheinbaum have both publicly embraced the concept of reconquista and actively discouraged Mexican Americans, much less Mexicans illegally present in the United States, from assimilating or in any way embracing American identity, the book reveals. Officials under both presidencies have declared illegal immigrants who send remittances home heroes and champion propaganda songs that celebrate rejecting American identity.

Article:

https://www.breitbart.com/politics/2026/01/22/shock-confession-mexican-president-admits-that-mass-migration-is-a-tool-to-reclaim-and-conquer-americas-southwest/

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AI-CHAT PRIME

Aac03-004

Talking With AI: The Not-so-Shocking Results

Quote:

The part that I found really interesting was that it so readily admitted to a pure fabrication, not once, mind you, but twice. Some, I suppose, will find this conversation frightening, and certainly I can understand that reaction, particularly if youre of the belief that AI wont get it wrong, particularly in areas its not touched on previously. Thats the reason I asked it about my call; its not a topic that a lot of folks would ask about. I wanted to see how it would handle itself in unfamiliar territory.

Comment:

Not having solid, hard learned logical concepts the way we humans do, AI Fabricates, halucinates, does many things to draw you in. And woe be you if you believe it without some sanity checks.

Article:

https://pjmedia.com/eric-florack/2026/01/19/talking-with-ai-the-not-so-shocking-results-n4948464

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PRIME CANCER

Mca03-016

Personalized Autoantibody Profiling Distinguishes Earlystage Breast Cancer from Benign Disease

Quote:

Conclusions This study identifies an eight-antibody panel with promising diagnostic potential to distinguish benign breast disease from early-stage breast cancer. The z-score normalization approach and analysis of individual donors high-titer antibody profiles represent a novel approach towards personalized cancer immunology.

Abstract:

https://www.medrxiv.org/content/10.64898/2026.01.15.26344214v1

Full Text:

https://www.medrxiv.org/content/10.64898/2026.01.15.26344214v1.full-text

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Kathryn A. Lyon Justin C. Rolando David R. Walt,

PRIME AGING BRAIN

Mep03-040

Accelerated multi-organ proteomic aging is detectable decades before dementia onset

Quote:

Among these is tumor necrosis factor receptor superfamily member 1B TNFRSF1B, causally implicated in the accelerated pace of brain, immune, muscle, and pancreas aging. Two other proteins associated with pace of brain aging, GM2 ganglioside activator GM2A and limbic system-associated membrane protein LSAMP, showed putative causal roles in multiple neurologic diseases.

Abstract:

https://www.medrxiv.org/content/10.64898/2026.01.16.26344299v1

Full Text:

https://www.medrxiv.org/content/10.64898/2026.01.16.26344299v1.full-text

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Fangyu Liu Wenyu Zhou Aditya Surapaneni Jingsha Chen Cassandra Joynes Pascal Schlosser Zulema Rodriguez-Hernandez Endre Sebestyn Hamilton Se-Hwee Oh Tony Wyss-Coray Gabriela T. Gomez Michael R. Duggan Anna Prizment Sanaz Sedaghat Shuo Wang Michael E. Griswold Josef Coresh Morgan E. Grams Keenan A. Walker,

PRIME HEART KIDNEYS LUNGS

Min03-008

Cardiovascular, renal and pulmonary risks of Long COVID: a retrospective cohort study stratified by age and sex

Quote:

Conclusions Long COVID is associated with increased risk of adverse CRP outcomes, with relatively higher risks observed in younger adults. These findings support the need for continuing surveillance and risk-reduction strategies for cardiovascular and related disorders in Long COVID.

Abstract:

https://www.medrxiv.org/content/10.64898/2026.01.14.26344156v1

Full Text:

https://www.medrxiv.org/content/10.64898/2026.01.14.26344156v1.full-text

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Search Authors:

Akash Pradeep Martha L Carvour Srija M Sivamurugan Upinder Singh Alejandro P Comellas Sanjana Dayal,

Search Words:

cardiovascular		Brave	Mojeek	Startpage	Dogpile	Bing	Googl	Lycos	Utub	Yaho
renal and pulmonary CRP		Brave	Mojeek	Startpage	Dogpile	Bing	Googl	Lycos	Utub	Yaho

PRIME AGING BRAIN SLEEP

Mne03-012

Sleep-like slow waves during resting-state: a promising EEG biomarker of amyloid and neurodegeneration in preclinical Alzheimer disease

Quote:

DISCUSSION Wake SW represent promising early EEG biomarkers for AD pathology and amyloid conversion, facilitating risk stratification before cognitive decline onset.

Abstract:

https://www.medrxiv.org/content/10.64898/2026.01.15.26344195v1

Full Text:

https://www.medrxiv.org/content/10.64898/2026.01.15.26344195v1.full-text

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Pierre Champetier Claudia Albero Filipa Raposo Pereira Rubn Herzog Maximilien Chaumon Marion Houot Maxime Locatelli Aurlie Kas Marie-Odile Habert Marc Teichmann Stphane Epelbaum Isabelle Arnulf Delphine Oudiette Thomas Andrillon span classnlm-collab data-hwp-idcollab-1INSIGHT-preAD group,

PRIME AGING BRAIN COGNITION PHYSICAL

Mne03-020

Physical fitness supports brain maintenance and cognitive reserve in cognitively normal aging: a cross-sectional examination

Quote:

Conclusion Muscular capacity was linked to lower BG PVS volumes, supporting resistance against pathology, while aerobic fitness related to preserved cortical integrity and tended to act as a CR proxy against MTL tau pathology. Physical fitness may support cerebrovascular and glymphatic function, thereby promoting cognitive resilience and extending healthspan by sustaining functional brain health and mitigating tau-related cognitive decline.

Abstract:

https://www.medrxiv.org/content/10.64898/2026.01.14.26344098v1

Full Text:

https://www.medrxiv.org/content/10.64898/2026.01.14.26344098v1.full-text

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Svenja Schwarck Niklas Behrenbruch Beate Schumann-Werner Ein N. Molloy Berta Garcia-Garcia Anne Hochkeppler Larissa Fischer Anna-Therese Bchel Enise I. Incesoy Jose Bernal Roberto Duarte Coello Maria d.C. Valds-Hernndez Joanna M. Wardlaw Niklas Vockert Patrick Mller Gusalija Behnisch Barbara Morgado Hermann Esselmann Constanze I. Seidenbecher Bjrn H. Schott Henryk Barthel Osama Sabri Jens Wiltfang Michael C. Kreissl Emrah Dzel Anne Maass,

PRIME AGING

Mnu03-020

A Novel NAD Supporting Supplement Increased NAD Levels, Improved Well-Being, and Alleviated Aging Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study

Quote:

A key factor in aging and many age-related diseases is the decline in nicotinamide adenine dinucleotide NAD levels. Preclinical studies demonstrate promising results for NAD boosting in improving conditions of disease or aging. ... Conclusions Qualia NAD increased NAD levels, enhanced quality of life in all participants, and alleviated some aging symptoms in females greater than placebo. The increase in NAD levels with Qualia NAD was greater than in most previous clinical trials of NAD supporting products at similar dosing, suggesting potential synergy between NR and the complementary nutrients in the product.

Abstract:

https://www.medrxiv.org/content/10.1101/2025.05.14.25327611v2

Full Text:

https://www.medrxiv.org/content/10.1101/2025.05.14.25327611v2.full-text

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Sarah A. Blomquist Gregory Kelly Sara Ades Christopher R. DAdamo Abhimanyu Ardagh Shawn Ramer William Scuba,

PRIME NUTRITION

Mph03-014

Hepatoprotective Efficacy of GeneIII L-Ergothioneine Capsules: A Self-Controlled Clinical Trial

Quote:

Erogothioniene EGT, a potent natural antioxidant, exerts hepatoprotection. ... Conclusion GeneIII L-Ergothioneine Capsules have a significant effect on improving liver function, physical function, and sleep quality in subjects, and the overall safety is good.

Abstract:

https://www.medrxiv.org/content/10.64898/2025.12.30.25343022v1

Full Text:

https://www.medrxiv.org/content/10.64898/2025.12.30.25343022v1.full-text

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Rujun He Wei Ding Juan Cao Hongying Ju Fengjuan Liu Guohua Xiao,

PRIME CENSORSHIP POLITICS

Zab03-000

Mike Johnson Ignites the UK Parliament in First-Ever Address by a Sitting US House Speaker

Quote:

From restoring, for example, secure borders that protect from the real and measurable harms of mass uncontrolled migration. From pushing back on policies that erode our citizens most basic liberties, especially the fundamental freedoms of speech and conscience. History teaches us: we can never go down the road of censoring and silence in unpopular opinions, because liberty is kept alive in the free marketplace of ideas. History further teaches us that the best solution to the problem of free speech is always more speech and those being unjustly persecuted for exercising those freedoms, such as Jimmy Lai, the British national being held in Hong Kong, must be defended. And the U.S. stands with the U.K. as you work to free him.

Article:

https://redstate.com/jenniferoo/2026/01/20/house-speaker-mike-johnson-inspires-the-uk-parliament-in-a-first-ever-address-by-a-sitting-us-speaker-n2198320

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PRIME PRIVACY RIGHTS

Zab03-008

GOP Rift Erupts After 57 Republicans Work With Democrats To Protect Orwellian Way To Shut Off Cars

Quote:

The vehicle kill-switch is precisely the kind of overreach that will empower regulatory agencies to manage behavior without votes by elected representatives in Congress or real accountability, Clyde Wayne Crews, the Fred L. Smith fellow in regulatory studies at the Competitive Enterprise Institute, said in a statement.

Comment:

The law, passed under Biden, states that all cars sold after 2026 must have a kill switch system. Existing systems are highly inaccurate.

Article:

https://dailycaller.com/2026/01/23/republicans-democrats-car-kill-switch-thomas-massie/

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PRIME PRIVACY

Zac03-000

Stores tracking you

Quote:

Surveilance runs on Correlation, not consensus. ... It is all about sensors... Deny apps pwermission to use your microphone. Muzzel your smart TV

Article:

http://youtube.com/watch?v=EVzhDH2q1Bs

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PRIME CANCER MICROBIOME

Zac03-005

Mummy Induces Apoptosis Through Inhibiting of Epithelial-Mesenchymal Transition EMT in Human Breast Cancer Cells

Quote:

According to previous reports, the efficacy of mummy associated with humic and fulvic acids, which are essential for its biochemical functions that these compounds represented to be very effective in decreasing inflammation, pain, arthritis, ulcer, diabetes, stress, anxiety, and the most importantly inducing the cell apoptosis in many cancers. Mummy, as a water-soluble non-toxic and inexpensive compound, can be consumed as a part of the daily diet 10 thus, further studies required to investigate the therapeutic effects of mummy and its active constituents as suitable candidates for chemotherapy.

Comment:

Iranians call it Mummy, Tibetans call it shilajit

Article:

https://pmc.ncbi.nlm.nih.gov/articles/PMC8343979/

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