Research
Topics:
INDEX
AI-chat 1
PRIME 18
aging 9
body 2
brain 10
cancer 11
censorship 1
cognition 4
covid-19 1
culture 2
dental 1
diabetes 1
gender 2
genetics 2
heart 8
immune 5
kidneys 6
language 1
lungs 7
metabolism 3
microbiome 3
nutrition 6
obesity 2
pain 2
physical 2
politics 2
pollution 2
practice 1
privacy 2
psychology 4
reproduction 1
rights 1
sleep 3
tech 1
virus 2
war-confl
 
Scanned: 2759
Evaluated: 288
Selected: 68

 
    PRIME    BRAIN    PRACTICE   

Aac03-001

Hidden Brain Injury behind Jordan Peterson -- Valium

Quote:Benzodiasophene, VALIUM
Article: https://youtube.com/watch?v=_q44phEpFjA
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    PRIME    AGING    BRAIN   

Mep03-040

Accelerated multi-organ proteomic aging is detectable decades before dementia onset

Quote:Among these is tumor necrosis factor receptor superfamily member 1B TNFRSF1B, causally implicated in the accelerated pace of brain, immune, muscle, and pancreas aging. Two other proteins associated with pace of brain aging, GM2 ganglioside activator GM2A and limbic system-associated membrane protein LSAMP, showed putative causal roles in multiple neurologic diseases.
Abstract: https://www.medrxiv.org/content/10.64898/2026.01.16.26344299v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.01.16.26344299v1.full-text
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Search Authors: Fangyu Liu Wenyu Zhou Aditya Surapaneni Jingsha Chen Cassandra Joynes Pascal Schlosser Zulema Rodriguez-Hernandez Endre Sebestyn Hamilton Se-Hwee Oh Tony Wyss-Coray Gabriela T. Gomez Michael R. Duggan Anna Prizment Sanaz Sedaghat Shuo Wang Michael E. Griswold Josef Coresh Morgan E. Grams Keenan A. Walker, 
    BRAIN   

Mne03-002

Temporal evolution acquisition based arterial spin labeling TEA-ASL for accurate arterial blood T2 mapping

Quote:The proposed TEA-ASL technique provides robust arterial T2 mapping at ultra-high field, offering a promising tool for probing oxygenation-related hemodynamics and BBB-associated pathophysiology.
Abstract: https://www.medrxiv.org/content/10.64898/2026.01.10.26343600v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.01.10.26343600v1.full-text
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Search Authors: Jiawen Sun Chenhe Yuan Junqi Xu Jiekai Zhu Ning Wang Yiling Liu Qing Wei Weihuan Fang Zhensen Chen Chenyan Wang He Wang Dengrong Jiang Peng Hu Fuhua Yan Hao Li Xingfeng Shao, 
Search Words:
Blood Braon Barrier BBB Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Temporal evolution acquisition based arterial spin labeling TEA-ASL Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    AGING    BRAIN   

Mne03-004

Alpha-synuclein propagation trajectories in a population-based postmortem cohort

Quote:we show that the spatial extent of #945;-synuclein pathology contributes to cognitive impairment independently of comorbid Alzheimers disease or transactive response DNA-binding protein 43 TDP-43 pathology. Together, these results provide a framework for patient stratification and for linking #945;-synuclein propagation patterns to clinical trajectories from prodromal to late stages.
Abstract: https://www.medrxiv.org/content/10.64898/2026.01.13.26343943v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.01.13.26343943v1.full-text
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Search Authors: Parsa Khalafi Jacob W Vogel Per Borghammer Anna Raunio Ville Kivist Sara Savola Eloise H Kok Elizaveta Mikhailenko Liisa Myllykangas Alain Dagher, 
    PRIME    AGING    BRAIN    SLEEP   

Mne03-012

Sleep-like slow waves during resting-state: a promising EEG biomarker of amyloid and neurodegeneration in preclinical Alzheimer disease

Quote:DISCUSSION Wake SW represent promising early EEG biomarkers for AD pathology and amyloid conversion, facilitating risk stratification before cognitive decline onset.
Abstract: https://www.medrxiv.org/content/10.64898/2026.01.15.26344195v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.01.15.26344195v1.full-text
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Search Authors: Pierre Champetier Claudia Albero Filipa Raposo Pereira Rubn Herzog Maximilien Chaumon Marion Houot Maxime Locatelli Aurlie Kas Marie-Odile Habert Marc Teichmann Stphane Epelbaum Isabelle Arnulf Delphine Oudiette Thomas Andrillon span classnlm-collab data-hwp-idcollab-1INSIGHT-preAD group, 
    BRAIN   

Mne03-018

Transformer-based EEG Source Imaging Enables Robust Localization of Pathological High-Frequency Oscillations in Epilepsy

Quote:These findings demonstrate that TH-DeepSIF provides a robust, data-driven framework for noninvasive HFO source imaging with improved anatomical specificity and enhanced clinical utility for presurgical evaluation using scalp EEG. Moreover, they show that pathological HFOs spike ripples rather than general HFOsserve as robust EEG biomarkers for accurate localization of the epileptogenic zone.
Abstract: https://www.medrxiv.org/content/10.64898/2026.01.14.26344110v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.01.14.26344110v1.full-text
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Search Authors: Jesse Rong Zhengxiang Cai Boney Joseph Gregory A. Worrell Bin He, 
    PRIME    AGING    BRAIN    COGNITION    PHYSICAL   

Mne03-020

Physical fitness supports brain maintenance and cognitive reserve in cognitively normal aging: a cross-sectional examination

Quote:Conclusion Muscular capacity was linked to lower BG PVS volumes, supporting resistance against pathology, while aerobic fitness related to preserved cortical integrity and tended to act as a CR proxy against MTL tau pathology. Physical fitness may support cerebrovascular and glymphatic function, thereby promoting cognitive resilience and extending healthspan by sustaining functional brain health and mitigating tau-related cognitive decline.
Abstract: https://www.medrxiv.org/content/10.64898/2026.01.14.26344098v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.01.14.26344098v1.full-text
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Search Authors: Svenja Schwarck Niklas Behrenbruch Beate Schumann-Werner Ein N. Molloy Berta Garcia-Garcia Anne Hochkeppler Larissa Fischer Anna-Therese Bchel Enise I. Incesoy Jose Bernal Roberto Duarte Coello Maria d.C. Valds-Hernndez Joanna M. Wardlaw Niklas Vockert Patrick Mller Gusalija Behnisch Barbara Morgado Hermann Esselmann Constanze I. Seidenbecher Bjrn H. Schott Henryk Barthel Osama Sabri Jens Wiltfang Michael C. Kreissl Emrah Dzel Anne Maass, 
    AGING    BRAIN    COGNITION   

Mne03-030

Lifelong trajectories of modifiable vascular risk factors and relation to cerebral small vessel disease in the Framingham Heart Study

Quote:Conclusions Individuals following high risk lifetime patterns of vascular risk factors have higher CSVD burden later in life. These results highlight the importance of primordial and primary prevention with sustained risk factor management across the lifespan to mitigate CSVD burden, a strong determinant of stroke and dementia risk.
Abstract: https://www.medrxiv.org/content/10.64898/2026.01.16.26344309v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.01.16.26344309v1.full-text
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Search Authors: Jose R. Romero Adlin Pinheiro Serkalem Demissie Hugo J. Aparicio Vasileios-Arsenios Lioutas Antreas Charidimou Alexa Beiser Oluchi Ekenze Jayandra J. Himali Charles DeCarli Sudha Seshadri Shariq Mohammed, 
Search Words:
Cerebral small vessel disease CSVD Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    BRAIN    PSYCHOLOGY   

Mpy03-004

Grey Matter Iron and Neuromelanin in Psychosis: A Systematic Review and Meta-Analysis of MRI Studies

Quote:Conclusions Psychosis is associated with lower subcortical iron-sensitive MRI values. This was most marked in the substantia nigra, where NM-MRI valueswhich index neuromelanin-bound iron in dopamine neuroneswere significantly higher. This suggests that while subcortical iron is overall lower in psychosis, neuromelanin-bound iron is increased within dopamine neurones. Investigating the mechanisms underlying iron alterations may provide new treatment targets.
Abstract: https://www.medrxiv.org/content/10.64898/2026.01.15.26344182v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.01.15.26344182v1.full-text
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Search Authors: Luke James Vano Jan Sedlacik Richard Carr Bernard Roch Bukala Oliver David Howes Robert Ali McCutcheon, 
    AGING    BRAIN    COGNITION    SLEEP   

Mpy03-022

Cross-sectional and longitudinal associations between sleep disturbances and psycho-affective symptoms in older adults: influence of amyloid positivity

Quote:Conclusions: In cognitively unimpaired older adults, associations between sleep disturbances and psycho-affective symptoms differ according to A#946; status. In A#946; individuals specifically, objective sleep fragmentation and instability are linked to psycho-affective vulnerability and brooding worsening over time. Sleep disturbances could thus represent early modifiable targets to mitigate psycho-affective symptomatology in older adults.
Abstract: https://www.medrxiv.org/content/10.64898/2026.01.15.26344227v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.01.15.26344227v1.full-text
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Search Authors: Claire Andr Edelweiss Touron Antoine Garnier-Crussard Andre-Ann Baril Gal Chtelat Sophie Dautricourt Natalie L. Marchant Graldine Rauchs span classnlm-collab data-hwp-idcollab-1Medit-Ageing Research Group, 

  Updated weekly. 01/24/2026-02:51:25 AM
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