Research
Topics:
INDEX
AI-chat 4
MCS 1
PRIME 19
PRIO 1
aging 13
brain 12
cancer 7
climate 1
cognition 6
covid-19 3
culture 1
dental 1
diabetes 5
diagnostics 4
gender 1
genetics 5
gut 1
heart 10
herbs 2
immune 5
language 1
lungs 1
metabolism 2
microbiome 3
nutrition 7
pain 2
politics 4
pollution 1
population 1
practice 1
psychology 6
reproduction 2
sleep 3
soc-media
tech 1
unk
war-confl
 
Scanned: 2728
Evaluated: 299
Selected: 66

 
    CANCER    DIAGNOSTICS    GENETICS   

Mca04-002

Whole Genome Sequencing Informed Patient Personalized Measurable Residual Disease Assays for Acute Myeloid Leukemia

Quote:In this study, we demonstrate a whole genome sequencing WGS-based approach to identify genomic DNA breakpoints of chromosomal rearrangements that allowed design of highly sensitive patient-personalized digital droplet PCR ddPCR MRD assays.
Abstract: https://www.medrxiv.org/content/10.64898/2026.01.22.26343677v2
Full Text: https://www.medrxiv.org/content/10.64898/2026.01.22.26343677v2.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Niveditha Ravindra Justin Lack Clifton L Dalgard Eddy vanCollenburg Adam Corner Lan Beppu Harry Erba Megan Othus Jerald P Radich Laura W Dillon Christopher S Hourigan, 
    GENETICS    HEART   

Mcr04-028

Epigenetics in Abdominal Aortic Aneurysm: Mechanisms and Risk Prediction

Quote:Conclusions This study identified putative causal DNA methylation markers for AAA, and multi-omics analyses implicate AP-1linked inflammatory transcriptional programs, blood lipids, platelet count, and multiple immune/inflammation-related proteins as key pathways underlying methylation-associated AAA risk.
Abstract: https://www.medrxiv.org/content/10.64898/2026.01.26.26344463v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.01.26.26344463v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Shuai Yuan Gabrielle Shakt Michael Levin Katherine Hartmann Renae Judy Tia Dinatale Amy Voorhees Julie A. Lynch Saiju Pyarajan Daniel Levy Roby Joehanes span classnlm-collab data-hwp-idcollab-1VA Million Veteran Program Kyong-Mi Chang Philip Tsao Benjamin F. Voight Gregory T Jones Scott M. Damrauer, 
    AGING    GENETICS   

Mep04-034

Association of epigenetic age acceleration with MRI biomarkers of aging and Alzheimers disease neurodegeneration

Abstract: https://www.medrxiv.org/content/10.64898/2026.01.23.26344650v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.01.23.26344650v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Linda K. McEvoy Bowei Zhang Steve Nguyen Adam X. Maihofer Caroline M. Nievergelt Ramon Casanova Steve Horvath Ake T. Lu Christos Davatzikos Guray Erus Susan M. Resnick Mark A. Espeland Stephen R. Rapp Kenneth Beckman Luigi Ferrucci Andrea Z. Lacroix Aladdin H. Shadyab, 
    DIABETES    GENETICS   

Mge04-002

Disentangling Type 2 Diabetes Risk and Comorbidity Using Genomic Structural Equation Modeling

Quote:Phenome-wide and comorbidity analyses revealed that each latent factor PGS associated with specific T2D-related complications and provided broader or distinct associations compared with conventional metabolic PGSs, with the obesity and lifestyle-related factor showing the widest impact. These findings illustrate how multivariate genetic approaches can disentangle the biological heterogeneity of T2D, refine polygenic risk prediction, and reveal mechanistic pathways driving divergent patterns of disease and comorbidity.
Abstract: https://www.medrxiv.org/content/10.64898/2026.01.26.26344825v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.01.26.26344825v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Merli Koitme Kristi Lll Mrt Mls Andrew P Morris Krista Fischer Reedik Mgi, 
    GENETICS   

Mpy04-026

Functional Genomic Analyses Reveal transfer RNA Modification Enzymes as Risk Genes for Bipolar I Disorder and Schizophrenia

Quote:The results show NSUN2 as a neuroprotective protein; shared cis-regulatory variations influencing both isoform-specific NSUN2 expression and disease risk. Several RMP genes, including NSUN6, TYW5, TRMT61A, and QTRT1, showed significant gene-level associations with BIPI or SCZ, implicating tRNA modification pathways more broadly. Together, these findings indicate that common genetic risks for BIPI and SCZ converge on regulatory variation affecting RNA modification machinery, nominating dysregulation of tRNA as a molecular pathway contributing to psychiatric disease susceptibility.
Abstract: https://www.medrxiv.org/content/10.64898/2026.01.26.26344826v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.01.26.26344826v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Li Bingwu Ohtan Wang, 

  Updated weekly. 01/31/2026-02:32:41 AM
Javilk's Research Links
Drop me a note to subscribe.
What interests you?