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Scanned: 1695
Evaluated: 92
Selected: 36
 
    IMMUNE    VACCINE    VIRUS   

Min08-012

Mapping the specificity of H3N2 strain-specific and cross-reactive human neutralizing antibodies elicited by the 2025-2026 influenza vaccine

Quote:Additional electron microscopy-based polyclonal epitope mapping studies confirmed that cross-reactive antibodies elicited by vaccination typically target epitopes on the side of HA. Together, our studies provide an immunological explanation of why the 2025-2026 influenza vaccine was partially effective against antigenically advance H3N2 subclade K viruses. Our data suggest that vaccine strains for subsequent seasons need to be carefully considered, since subclade K viruses have already started to acquire additional substitutions in HA antigenic sites targeted by cross-reactive antibodies.
Abstract: https://www.medrxiv.org/content/10.64898/2026.02.20.26346746v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.02.20.26346746v1.full-text
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Search Authors: Jiaojiao Liu Sydney Gang Caroline Kikawa Alesandra J. Rodriguez Shuk Hang Li Naiqing Ye Tachianna Griffiths Elizabeth M Drapeau Reilly K. Atkinson Andrea N. Loes Ronald G. Collman James A. Ferguson Julianna Han Andrew B. Ward Jesse D. Bloom Scott Hensley, 
    PRIVACY    VIRUS   

Min08-020

Mapping spatial colleague connectivity patterns from individual-level registry data to inform regional pandemic interventions

Quote:These results suggest that the impact of regional interventions shifting spatial connectivity patterns should be expected to vary by region and type of intervention. Together, our findings draw attention of using this highly fine-grained spatial connectivity to enable more regionally tailored and network-targeted policy measures.
Abstract: https://www.medrxiv.org/content/10.64898/2026.02.19.26346499v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.02.19.26346499v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: PingPing Song Sake J. de Vlas Tom Emery Luc E. Coffeng, 

  Updated weekly. 02/25/2026-08:05:42 PM
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