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Min10-026

Impact of vaccination on the speed of antigenic evolution

Quote:When transmission is substantially suppressed, antigenic evolution slows down. However, when vaccines match circulating strains but confer narrow cross-immunity, vaccination may accelerate antigenic evolution and potentially increase incidence. In a case study of seasonal influenza, vaccines with increased efficacy can speed up antigenic evolution but do not raise incidence. Overall, our results show that vaccination can effectively reduce both infection incidence and the speed of antigenic evolution in many scenarios. Nevertheless, the potential for vaccine-driven evolution warrants careful consideration, particularly when vaccine effectiveness in reducing incidence is limited.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.10.26347605v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.10.26347605v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Myrthe Sophie Willemsen Ganna Rozhnova, 

  Javilk's Research Links for Week 10
Updated 03/15/2026-01:54:15 AM
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