| Research Topics: |
| INDEX |
| AI-chat 7 |
| PRIME 20 |
| aging 9 |
| brain 8 |
| brainwave 2 |
| cancer 5 |
| censorship 1 |
| climate 1 |
| cognition 4 |
| covid-19 1 |
| culture 1 |
| dental 1 |
| diabetes 3 |
| economy 5 |
| exercise 1 |
| gender 1 |
| genetics 1 |
| gut 1 |
| heart 10 |
| herbs 1 |
| immune 4 |
| kidneys 2 |
| language 1 |
| law 1 |
| lungs 3 |
| metabolism 1 |
| microbiome 1 |
| misc |
| nutrition 7 |
| politics 5 |
| pollution 1 |
| population 1 |
| psychology 1 |
| reproduction 3 |
| sleep 1 |
| soc-media |
| space 1 |
| unk |
| vaccine 2 |
| virus 2 |
| war-confl |
|
Scanned: 2665 Evaluated: 236 Selected: 60 |
| PRIME AGING BRAIN NUTRITION | ||||||||
Aaa11-000 | Health Benefits of Vitamin B 12 | |||||||
| Quote: | Low vitamin B12 impact on brain aging A recent study in the June 2025 issue of the journal Annals of Neurology researchers suggested that low blood levels of vitamin B12 are associated with increased risk for cognitive impairment and dementia. While it has b een generally accepted that there is an association between B12 deficiency and neurological dysfunction, this studys objective was to assess whether B12 levels within the current normal range in a cohort of healthy older adults may be associated with measurable evidence of neurological injury or dysfunction. | |||||||
| Article: | https://richardgoldberg.substack.com/p/health-benefits-of-vitamin-b-12 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Richard Goldberg, Felton Nutrition, | |||||||
| PRIME AGING BRAIN | ||||||||
Aaa11-034 | A brain-persistent DDR2-degrading antibody reverses Alzheimers pathologies by restoring brain fluid dynamics and metabolic clearance | |||||||
| Quote: | CONCLUSION This study identifies DDR2 as a master regulator of multi-compartmental failure in AD, orchestrating dysfunction across cerebral vasculature, CSF dynamics, and the choroid plexus. We developed a monoclonal antibody that drives durable internalization and lysosomal degradation of DDR2; when delivered via a neuron-tropic AAV, it achieves sustained CNS expression and confers broad therapeutic efficacy against AD. A companion DDR2-targeted PET tracer enables noninvasive visualization of target engagement in vivo. Together, this integrated platform establishes a new paradigm for disease-modifying therapy in AD. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.17.26348575v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.17.26348575v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Penghui Yang xu chen jiuyang Ding yuzhou Peng zhixiang Lei Jin Su, | |||||||
| AGING | ||||||||
Mep11-020 | Frailty progression following severe infections in adults aged 65 years and above in US and England: two matched cohort studies | |||||||
| Quote: | Effects varied by infection type strongest for lower respiratory tract infections, meningoencephalitis UK only, urinary tract infections, and sepsis. Interpretation Individuals with severe infections had higher frailty at baseline and follow up than those without. Preventing both frailty and infections is important for improving health in older age. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.13.26348319v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.13.26348319v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Kwabena Asare Kathryn E Mansfield Georgia R Gore-Langton Sharon L Cadogan Eleanor Barry Ruth Keogh Vincent Lo Re span classnlm-suffixIII Maria C. Rodriguez-Barradas Amy C. Justice Christopher T. Rentsch Charlotte Warren-Gash, | |||||||
| AGING KIDNEYS | ||||||||
Mkd11-022 | Chronic Kidney Disease Amplifies Gabapentin-Associated Dementia Risk: Evidence for a Renal Pharmacokinetic Mechanism | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.15.26348418v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.15.26348418v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | James W Green Laura Byham Gray Joshua Kaplan Suril Gohel Barbara Tafuto, | |||||||
| AGING BRAIN IMMUNE | ||||||||
Mne11-014 | Single-cell multi-omic profiling allows the dissection of peripheral immune phenotypes in Alzheimers Disease progression | |||||||
| Quote: | Classical monocytes expanded in mild cognitive impairment and early AD dementia, acquiring a NF-kB/AP-1-mediated low-grade inflammation phenotype. Our findings link peripheral dysregulation in innate and adaptive immunity at cell frequency, transcriptional and epigenetic levels to the AD trajectory and provide insights into distinct phenotypes that define AD progression in contrast to healthy aging across cohorts. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.12.26348228v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.12.26348228v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Jannis B Spintge Karola Mai Caterina Carraro Martina van Uelft Francesco Elli Karoline Mauer Lisa Holsten Aleksej Frolov Janice Elangikal Emily Hinkley Jonas Schulte-Schrepping Mehrnoush H Shakiba Laura Lang Tarek Elmzzahi Doaa Hamada Sophie Mller Yuanfang Li Ioanna Gemnd Charlotte Krger Jacqueline Leidner Timo Zajac Jessica V Montgomery Celia Hartmann Bidour Hussein Maren Bttner Rainer Knoll Dina Hsson Rebekka Scholz Tobias Paschek Victoria Isakzai Nico Reusch Stefan Paulusch Anna Drews Michael Kraut Heidi Theis Marie Rthing Ulrike Strube Lukas Preis Daria Gref Eike J Spruth Maria Gemenetzi Klaus Fliessbach Niels Hansen Ayda Rostamzadeh Wenzel Glanz Enise I Incesoy Daniel Janowitz Sophia Stcklein Boris-Stephan Rauchmann Ingo Kilimann Doreen Goerss Sebastian Sodenkamp Marie Kronmller Sandra Roeske Anna Gamez Matthias Schmid Katharina Brger Julian Hellmann-Regen Christoph Laske Alfredo Ramirez Frederic Brosseron Jens Wiltfang Robert Perneczky Emrah Dzel Stefan Teipel Annika Spottke Gabor C Petzold Oliver Peters Josef Priller Susanne V Schmidt Michael Wagner Luca Kleineidam Frank Jessen Anja Schneider Lorenzo Bonaguro Elena De Domenico Anna C Aschenbrenner Matthias Becker Thomas Ulas Joachim L Schultze Marc D Beyer, | |||||||
| AGING BRAIN SLEEP | ||||||||
Mne11-016 | Vascular brain injury modifies the relationship between sleep duration, cognition, and white matter hyperintensity burden in the Alzheimers disease continuum | |||||||
| Quote: | INTRODUCTION Self-reported sleep duration is associated with dementia-risk and vascular brain injury markers, including white matter hyperintensities WMHs, DISCUSSION Additional vascular brain injury modifies how sleep relates to WMH burden and cognition across the AD continuum, highlighting the importance of moving beyond WMHs alone. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.12.26348239v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.12.26348239v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Soraya Lahlou Zahinoor Ismail Eric E. Smith Thien Thanh Dang-Vu AmanPreet Badhwar, | |||||||
| PRIME AGING BRAIN BRAINWAVE COGNITION | ||||||||
Mne11-018 | Theta deep-brain stimulation improves cognitive performance in Parkinsons patients with cognitive impairments | |||||||
| Quote: | Conclusions These data suggest that theta-frequency 4 Hz STN stimulation is effective in PD patients with cognitive impairments. Our findings will help guide new therapies targeted at improving cognitive dysfunction in PD and could broaden applications for low-frequency brain stimulation. ### Competing Interest Statement | |||||||
| Comment: | I find that the Schuman frequency, the general frequency of the geomagnetic field oscillations averaging 7.83hz, is more more effective in improving memory, while anything below 5hz physiologically impares memory formation and induces sleep mode paralysis top prevent sleep-walking, etc. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.12.26348246v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.12.26348246v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Rachel C. Cole James F. Cavanagh Qiang Zhang Christopher L. Groth Juan Vivanco-Suarez Arturo I. Espinoza Jeremy D. Greenlee Nandakumar S Narayanan, | |||||||
| AGING | ||||||||
Mne11-030 | Comparative Analysis of Task-Specific and Combined Upper-Limb EMG Features for Early Parkinsons Disease Classification | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.16.26348216v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.16.26348216v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Jlia Rey Vilches Chiara Gorlini Silvia Tolu Trine Hrmann Thomsen Bo Biering-Srensen Sadasivan Puthusserypady, | |||||||
| AGING | ||||||||
Mne11-036 | Hearing Loss as a Modifiable Risk Factor for Dementia | |||||||
| Quote: | This study evaluated hearing loss HL as a potential early indicator of dementia. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.16.26348518v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.16.26348518v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Abigail Dichter Ella J. Lee Timothy Park Karen Tawk Elham Ghanbarian Mehdi Abouzari, | |||||||
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Javilk's Research Links for Week 11 Updated 03/20/2026-10:37:02 PM What interests you? What have you found? Tell me! Drop me a note to subscribe or submit something. |