PRIME DIABETES EXERCISE HEART
Mcr11-028	Cardiometabolic health and the timing of habitual exercise in the All of Us Research Program
	Quote:	Compared to daytime exercise, habitual morning exercise was associated with lower odds of coronary artery disease OR 0.69; CI 0.55 0.87, hypertension OR 0.82; CI 0.72 0.94, type 2 diabetes OR 0.70; CI 0.58 0.85, hyperlipidemia OR 0.79; CI 0.69 0.90, and obesity OR 0.65; CI 0.55 0.77. These associations were independent of total physical activity volume and remained consistent across hour of day analyses, with the lowest risk nadir occurring between 07:00 08:00 for coronary artery disease.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.03.16.26348509v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.03.16.26348509v1.full-text
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	Search Authors:	Prem Patel Connor Riegal Asanish Kalyanasundaram Manjot Singh Keerthenan Raveendra Michael Y. Mi Usman A. Tahir Jeremy M. Robbins Gaurav Tiwari Nicholas S. Peters Tamar Sofer Daniel B. Kramer Robert E. Gerszten Prashant Rao,
DIABETES
Mdb11-026	Causal Mediation Pathways in Continuous Postprandial Glucose Monitoring for Type 1 Diabetes Patients
	Quote:	At dinner, the direct glycemic effect substantially exceeds the insulin-mediated response, producing persistent total effects of 1014 mg/dL for a 30 g carbohydrate increase that indicates systematic under-compensation by evening boluses. Breakfast, in contrast, exhibits large but nearly canceling direct and mediated effects, while lunch and snack show negligible mediation structures. Quantile-specific analysis further identifies a subgroup for whom the total carbohydrate effect at dinner reaches 22.03 mg/dL p 0.04, statistically significant despite being undetectable in the mean-level analysis. This distributional heterogeneity points to patients whose glycemic risk is undermined by population-average estimates and for whom current dosing recommendations are inadequate.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.03.16.26348520v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.03.16.26348520v1.full-text
	Search Similar:	Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho
	Search Authors:	Spencer Hilligoss Annie Qu,
PRIME DIABETES LANGUAGE
Mdb11-030	Detection of Type 2 Diabetes from 20-second Speech Recordings: A Large-Scale Validation Study
	Quote:	Here, we present the largest known real-world validation study for a speech-based T2D prediction model, trained on speech data from over 21,000 individuals, that works on features extracted from 20-second speech recordings.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.03.16.26348468v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.03.16.26348468v1.full-text
	Search Similar:	Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho
	Search Authors:	Elisa Brann Roseline Polle Giedr epukaityt Alexandra L. Georgescu Owen Parsons Emilia Molimpakis Stefano Goria,

Javilk's Research Links for Week 11
Updated 03/20/2026-10:37:02 PM
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Mcr11-028

Cardiometabolic health and the timing of habitual exercise in the All of Us Research Program

Mdb11-026

Causal Mediation Pathways in Continuous Postprandial Glucose Monitoring for Type 1 Diabetes Patients

Mdb11-030

Detection of Type 2 Diabetes from 20-second Speech Recordings: A Large-Scale Validation Study