Research
Topics:
INDEX
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PRIME 20
aging 9
brain 8
brainwave 2
cancer 5
censorship 1
climate 1
cognition 4
covid-19 1
culture 1
dental 1
diabetes 3
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exercise 1
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genetics 1
gut 1
heart 10
herbs 1
immune 4
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microbiome 1
misc
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soc-media
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unk
vaccine 2
virus 2
war-confl
 
Scanned: 2665
Evaluated: 236
Selected: 60

 
    GENETICS    HEART    LUNGS   

Mcr11-002

Heart-lung connections: Phenotypic and genetic insights from a large-scale genome-wide cross-trait analysis

Quote:Overall, the genetic basis between CVDs and RTs was inconsistent with vertical pleiotropy, suggesting the dramatic impact of horizontal pleiotropy. Conclusions: Our findings indicate widely distributed pleiotropic genetic determinants between RTs and CVDs across the genome. These results support a common genetic basis for RTs and CVDs and are important for intervention and therapeutic targets in comorbidities.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.15.24309272v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.15.24309272v1.full-text
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Search Authors: Jun Qiao Kaixin Yao Shiyu Zheng Minjing Chang Pengwei Zhang Yuqing Yang Yuxiao Kong Yao Qiao Jinyi Chen Ziyi Han Jialin Hou Ning Tan Ling Wang Pengcheng He Guo-chang Fan Sakthivel Sadayappan Anil G. Jegga Lei Jiang Yuliang Feng, 
    HEART   

Mcr11-006

Feasibility and safety of long-term remote-only monitoring in a large cohort of pacemaker patients

Quote:Conclusion Our real-word data indicate that RM-only offers an efficient and safe method for long-term follow-up of pacemaker patients.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.12.26348292v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.12.26348292v1.full-text
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Search Authors: Markus Sane Toni Jntti Annukka Marjamaa Elina Pennanen Charlotte Aura Eeva Torvinen Leena Karjalainen Jarkko Karvonen Pekka Raatikainen, 
    HEART   

Mcr11-008

One Day Hospital Initiation of Oral Sotalol The Cmax ss Test Strategy

Quote:BACKGROUND Sotalol loading intravenously enables achieving blood levels of sotalol that are observed at maximal steady-state concentration Cmax ss in one-day permitting the measurement of maximum QTc effects. Rapid evaluation of the QTc effects permits determination of arrhythmic risk and thus permits discharge in 24-hours instead of the usual three-day oral load hospitalization.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.12.26348293v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.12.26348293v1.full-text
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Search Authors: Janos Molnar John Somberg, 
    HEART    IMMUNE   

Mcr11-010

Longitudinal immune transcriptomic signatures are associated with carotid intimamedia thickness over 18 years

Quote:Conclusions PBMC transcriptional profiles are associated with subclinical vascular remodeling both cross-sectionally and over long-term follow-up, suggesting that systemic immune transcriptional states may contribute to vascular aging.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.12.26348144v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.12.26348144v1.full-text
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Search Authors: Anna DAntuono Giacomo Fantoni Elisabetta Giordano Valentina Spigoni Federica Fantuzzi Francesca Bagnaresi Gloria Cinquegrani Raffaella Aldigeri Francesco Balzam Cristina Branchi Mario Lauria Riccardo C. Bonadonna Luca Marchetti Alessandra Dei Cas, 
    HEART   

Mcr11-012

Increased Risk of Heart Rhythm Abnormalities in Adolescents and Young Adults who Vape: A Retrospective Cohort Study.

Quote:Conclusion This study shows a significant association between e-cigarette use and an increased risk of heart rhythm abnormalities in AYA. These findings highlight the potentially harmful cardiac electrophysiological outcomes of vaping in this population and underscore the importance of health interventions and surveillance.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.12.26348232v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.12.26348232v1.full-text
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Search Authors: Athanasios Tsalatsanis Joyce Johnson Obada Abou-Assali Shone Almeida Racha Khalaf Sami Noujaim, 
    AI-CHAT    HEART   

Mcr11-022

CARDIAC-FM: A Multimodal Foundation Model for Cardiovascular Risk Prediction Using ECG and Cardiac MRI

Quote:The learned representations improved prediction across a range of cardiovascular outcomes with minimal task-specific fine-tuning, reflecting real-world settings where many diseases have limited positive samples and lack dedicated risk models. Although trained on paired ECG and MRI data, CARDIAC-FM generates predictions using ECG alone or ECG combined with established risk scores, enabling broad clinical deployment without MRI. These findings demonstrate the promise of multimodal pre-training for generalizable cardiovascular risk prediction.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.16.26348526v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.16.26348526v1.full-text
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Search Authors: Fumin Li Siting Li Yuhan Qian Bojun Chen Jennifer A Brody Vidhushei Yogeswaran Kerri L Wiggins Colleen M Sitlani Joshua C Bis Ali Shojaie W T Longstreth span classnlm-suffixJr. Bruce M Psaty Geoffrey H Tison Simon Du James S Floyd Ting Ye, 
    PRIME    DIABETES    EXERCISE    HEART   

Mcr11-028

Cardiometabolic health and the timing of habitual exercise in the All of Us Research Program

Quote:Compared to daytime exercise, habitual morning exercise was associated with lower odds of coronary artery disease OR 0.69; CI 0.55 0.87, hypertension OR 0.82; CI 0.72 0.94, type 2 diabetes OR 0.70; CI 0.58 0.85, hyperlipidemia OR 0.79; CI 0.69 0.90, and obesity OR 0.65; CI 0.55 0.77. These associations were independent of total physical activity volume and remained consistent across hour of day analyses, with the lowest risk nadir occurring between 07:00 08:00 for coronary artery disease.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.16.26348509v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.16.26348509v1.full-text
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Search Authors: Prem Patel Connor Riegal Asanish Kalyanasundaram Manjot Singh Keerthenan Raveendra Michael Y. Mi Usman A. Tahir Jeremy M. Robbins Gaurav Tiwari Nicholas S. Peters Tamar Sofer Daniel B. Kramer Robert E. Gerszten Prashant Rao, 
    HEART   

Mcr11-036

A circulating extracellular vesicle-bound fraction of cardiac troponin discriminates myocardial homeostasis and disease states

Quote:Conclusions This study introduces the relative EV-troponin fraction as a novel biomarker in cardiovascular disease, improving diagnostic specificity for ischemic and non-ischemic myocardial disease entities.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.16.26348488v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.16.26348488v1.full-text
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Search Authors: Jona Benjamin Krohn Dominika Bernath-Nagy Yuetong Leona Ding Melek Sukran Kalinyaprak Gabriel Jakob Trauner Chiara Hess Felix Wiedmann Constanze Schmidt Hugo Katus Norbert Frey Florian Leuschner Evangelos Giannitsis, 
    DENTAL    HEART   

Mep11-014

Oral-Cardiovascular Links via Blood Biomarkers: An Exposure-Wide Analysis

Quote:Results: We found that indicators regarding caries, periodontal status, and occlusal function were significantly associated with carotid plaque prevalence. Sex-stratified analyses confirmed that all significant associations were concentrated in females, instead of males. Age-stratified analyses showed distinct patterns, with meaningful associations concentrated among participants under 65, where indicators regarding caries, periodontal status, and occlusal function were related to the FRS. In adults aged 65 and older, only the number of functional tooth units was associated with carotid plaque.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.13.26348364v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.13.26348364v1.full-text
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Search Authors: Yanbei Lu Zhiheng Yi Yanjia Zhuang Dasen Yuan Lei Lei He Cai Tao Hu, 
    GENDER    HEART   

Mge11-018

Multi-trait and Gene-Based Analyses Identify Genetic Variants Associated with Spontaneous Coronary Artery Dissection

Quote:Background and aims Spontaneous coronary artery dissection SCAD is a non-atherosclerotic cause of acute myocardial infarction MI that predominantly affects young women. ,... Our findings implicate key arterial-wall pathways beyond extracellular matrix organization, and point at relevant biological mechanisms in non-atherosclerotic dissection. These findings nominate tractable targets for experimental follow-up and support future efforts toward SCAD risk stratification in women.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.12.26348247v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.12.26348247v1.full-text
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Search Authors: Takiy-Eddine Berrandou Adrien Georges Ingrid Tarr Eleni Giannoulatou Robert M Graham Doug Speed Nabila Bouatia-Naji, 

  Javilk's Research Links for Week 11
Updated 03/20/2026-10:37:02 PM
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