Research
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Scanned: 2629
Evaluated: 248
Selected: 73
 
    PRIME    BRAIN    COGNITION    PSYCHOLOGY   

Aaa12-004

Oxidative Stress May Drive Repetitive Behaviors Linked to Autism, OCD

Quote:Summary: A new study shows that oxidative stressan imbalance between damaging molecules and antioxidantsmay contribute to repetitive behaviors observed in mice, similar to those seen in autism spectrum disorder and schizophrenia. Researchers found that higher levels of oxidative stress biomarkers, including glutathione and specific proteins, were linked to more severe stereotypies in young mice. These protein profiles were consistent across different mouse strains, suggesting a robust biological connection. The findings reveal new potential biomarkers and therapeutic targets for repetitive behavior disorders, though more research is needed to confirm whether antioxidant treatments could help.
Comment: The brain concentrates C in the body. The first things I noticed when taking vitamin C at near bowel tolerance levels, is improved brain function, deeper perception and better memory.
Article: https://neurosciencenews.com/oxidative-stress-asd-ocd-29902/
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See Also:
  • http://mall-net.com/cathcart/titrate.html
    •     PRIME    BRAIN    NUTRITION    POLLUTION   

    Aac12-002

    Parkinsons risk increases with exposure to common chemical, study suggests Long-term exposure to chlorpyrifos could more than double risk, say researchers, but other factors could play a role

    Quote:A UCLA study published in the journal Springer Nature Link suggests that exposure to chlorpyrifos could increase the risk of the neurological disease. The chemical is often used on agricultural products like soybeans, fruit and nut trees, broccoli, cauliflower and other row crops, according to the U.S. Environmental Protection Agency.
    Article: https://www.foxnews.com/health/parkinsons-risk-increases-exposure-common-chemical-study-suggests
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        BRAIN   

    Mne12-006

    Delayed Transcallosal Conduction to the Lesioned Sensorimotor Cortex in Multiple Sclerosis: A combined TMS 7T-MRI Study

    Quote:Conclusions The presence of cortical lesions in the sensorimotor cortex affects transcallosal inhibition between homologous sensorimotor regions in MS, slowing the build-up of inhibitory influence on the corticospinal output in the lesioned cortex. This delayed inhibitory build#8209;up appears to be associated with an intracortical lesion type.
    Abstract: https://www.medrxiv.org/content/10.64898/2026.03.20.26348903v1
    Full Text: https://www.medrxiv.org/content/10.64898/2026.03.20.26348903v1.full-text
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    Search Authors: Mads Alexander Just Madsen Lasse Christiansen Vanessa Wiggermann Henrik Lundell Jeppe Romme Christensen Morten Blinkenberg Finn Sellebjerg Hartig R Siebner, 
        AGING    BRAIN    COGNITION    HEART   

    Mne12-010

    Middle aged carotid plaque and cognitive functions in later life: a population-based study. Middle aged carotid plaque and cognitive functions in later life: a population-based study.

    Quote:Discussion: In this large cohort study, carotid plaque status at baseline was independently associated with in cognitive function decline, especially in non-verbal memory and executive functioning over 8-year follow-up period in the general population. Therefore, it may be important for earlier intervention on carotid plaque to preserve neurological health in middle-aged to older population.
    Abstract: https://www.medrxiv.org/content/10.64898/2026.03.23.26349039v1
    Full Text: https://www.medrxiv.org/content/10.64898/2026.03.23.26349039v1.full-text
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    Search Authors: Gisung Shin Ali Tanweer Siddiquee Min-Hee Lee June Christoph Kang Yoonho Hwang Seungku Lee Bongjo Kim Youngjin Kim Chol Shin Nanhee Kim Gisung Shin Ali Tanweer Siddiquee Min-Hee Lee June Christoph Kang Yoonho Hwang Seungku Lee Bongjo Kim Youngjin Kim Chol Shin Nanhee Kim, 
        AGING    BRAIN    COGNITION   

    Mne12-020

    The Case Against the S: Is Functional Neurological Disorders One Condition or Many? The Case Against the S: Is Functional Neurological Disorders One Condition or Many?

    Quote:Our results suggest that the symptom structure of FND is the result of a single pathophysiological process, either as a single entity, or a common pathway preceded by multiple causative processes where the common pathway is solely responsible for the phenotype of the condition.
    Abstract: https://www.medrxiv.org/content/10.64898/2026.03.19.26348846v1
    Full Text: https://www.medrxiv.org/content/10.64898/2026.03.19.26348846v1.full-text
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    Search Authors: David D. G. Palmer Mark J. Edwards Jason Mattingley David D. G. Palmer Mark J. Edwards Jason Mattingley, 
        BRAIN    BRAINWAVE   

    Mne12-022

    Therapeutic Efficacy and Safety of Deep Brain Stimulation for Multiple Sclerosis Related-Tremor: A Systematic Review and Meta-Analysis

    Quote:Conclusion: Deep brain stimulation may provide meaningful tremor reduction in selected patients with disabling and medication refractory MS tremor, with a large pooled treatment effect SMC 1.42. Although complications such as postoperative infection approximately 7 and transient stimulation related adverse effects can occur, these events appear manageable in most cases.
    Abstract: https://www.medrxiv.org/content/10.64898/2026.03.22.26349017v1
    Full Text: https://www.medrxiv.org/content/10.64898/2026.03.22.26349017v1.full-text
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    Search Authors: Farzan Fahim MohammadAmin Farajzadeh Seyyed Mohammad Hosseini Marvast Mahsa Faramin Lashkarian Ava Khalili Dehkord Parastoo Sangtarashha Reihane Qahremani Hadis Khodadadi Mahdieh Pourabdollah Taha Mahdian Setareh Parsakian MohammadReza Toghyani Sayeh Oveisi Guive Sharifi Alireza Zali Farbod Tabasi Kakhki AmirMahdi Mojtahedzadeh, 
        AGING    BRAIN   

    Mne12-034

    Multidomain determinants of perivascular spaces indicate early cerebrovascular vulnerability in individuals at risk of Alzheimers disease

    Quote:Determinants of PVS burden showed marked regional specificity. In the centrum semiovale, PVS burden was associated with age, male-sex and cardiometabolic factors. In contrast, hippocampal and midbrain PVS were more closely related to AD biomarker status and to psychological or sleep-related measures. Pronounced sex differences were observed, with men exhibiting higher PVS burden in centrum semiovale, while women showed higher PVS counts in the hippocampus, midbrain and basal ganglia.
    Abstract: https://www.medrxiv.org/content/10.64898/2026.03.23.26349050v1
    Full Text: https://www.medrxiv.org/content/10.64898/2026.03.23.26349050v1.full-text
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    Search Authors: Alba Fernandez-Bonet Gerard Temprano-Sagrera Patricia Genius Blanca Rodriguez-Fernandez Eugenia Domingo-Guell Jordi Huguet Mariateresa Buongiorno Gonzalo Sanchez Benavides Marta Cirach Mark Nieuwenhuijsen Marleen de Bruijne Tavia E Evans Natalia Vilor-Tejedor, 
        AGING    BRAIN    LANGUAGE   

    Mne12-040

    Structured retrieval closes the gap between low-cost and frontier clinical language models Structured retrieval closes the gap between low-cost and frontier clinical language models

    Quote:These findings indicate that retrieval architecture, rather than model scale alone, is a tractable lever for robust, equitable clinical LLM deployment.
    Abstract: https://www.medrxiv.org/content/10.64898/2026.03.22.26349018v1
    Full Text: https://www.medrxiv.org/content/10.64898/2026.03.22.26349018v1.full-text
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    Search Authors: Alon Gorenshtein Moran Sorka Mahmud Omar Keren Miron Adi Hatav Yiftach Barash Eyal Klang Shahar Shelly, 
        BRAIN    PAIN   

    Mpa12-022

    Structural and Functional Alterations of the Dorsolateral Prefrontal Cortex Across Chronic Pain Cohorts

    Quote:These findings indicate consistent structural and functional alterations across chronic pain cohorts.
    Abstract: https://www.medrxiv.org/content/10.64898/2026.03.24.26349122v1
    Full Text: https://www.medrxiv.org/content/10.64898/2026.03.24.26349122v1.full-text
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    Search Authors: Morihiko Kawate Saki Takaoka Yuta Shinohara Yihuan Wu Yuki Mashima Chisato Tanaka Naho Ihara Takashige Yamada Shizuko Kosugi Kenta Wakaizumi, 
        BRAIN    PAIN   

    Mpa12-026

    Meta-analytic Evidence for Four Amplifier Loops in Chronic Pain Chronification: Development of the Pain Amplifier Loop Framework PALF Risk Score

    Quote:Conclusions Four amplifier loops independently and substantially increase chronic pain risk, with the iatrogeni
    Abstract: https://www.medrxiv.org/content/10.64898/2026.03.22.26348998v1
    Full Text: https://www.medrxiv.org/content/10.64898/2026.03.22.26348998v1.full-text
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    Search Authors: Javier Arranz-Duran, 
        BRAIN    PSYCHOLOGY   

    Mpy12-024

    Longitudinal associations between depressive symptoms and brain structure across late childhood and adolescence: A panel network analysis study

    Quote:Cross-domain brain-symptom associations emerged only at the within-person level, where elevated depressed mood was associated with contemporaneous and subsequent reductions in cingulate and fusiform gyrus thickness partial r -0. 02 - 0. 04. No cross-domain associations were detected in the between-person networks. Sex-differences emerged only in the within-person networks. Conclusions: Associations between brain structure and depressive symptoms were subtle, symptom-specific, and dynamic rather than reflecting stable individual differences.
    Abstract: https://www.medrxiv.org/content/10.64898/2026.03.24.26349162v1
    Full Text: https://www.medrxiv.org/content/10.64898/2026.03.24.26349162v1.full-text
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    Search Authors: Eira Ranheim Aksnes Dani Beck Niamh MacSweeney Marieke Bos Lia Ferschmann Linn B. Norbom Valerie C. Karl Lars T. Westlye Christian K. Tamnes, 
        BRAIN    HEART   

    Msm12-022

    Effects of HIIT and HIIT plus Resistance Training on Cerebral Blood Flow and Other Health Outcomes in Individuals with Coronary Artery Disease: The Heart-Brain Randomized Controlled Trial

    Quote:Conclusion: Twelve weeks of HIIT RT or HIIT did not increase CBF in the whole sample with CAD, but HIIT effectively increased CBF in those who had poorer CBF at baseline.
    Abstract: https://www.medrxiv.org/content/10.64898/2026.03.23.26347205v1
    Full Text: https://www.medrxiv.org/content/10.64898/2026.03.23.26347205v1.full-text
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    Search Authors: Lucia Sanchez-Aranda Angel Toval Esmee A. Bakker Patricio Solis-Urra Isabel Martin-Fuentes Javier Fernandez-Ortega Rosa Maria Alonso-Cuenca Marcos Olvera-Rojas Beatriz Fernandez-Gamez Andrea Coca-Pulido Alberto Gonzalez-Garcia Dario Bellon Alessandro Sclafani Javier Sanchez-Martinez Ricardo Rivera-Lopez Norberto Herrera-Gomez Emilio J. Barranco-Moreno Francisco J. Amaro-Gahete Anna Carlen Jairo H. Migueles Danny J.J. Wang Kirk I. Erickson Eduardo Moreno-Escobar Rocio Garcia-Orta Irene Esteban-Cornejo Francisco B. Ortega, 

      Javilk's Research Links for Week 12
    Updated 03/27/2026-11:59:04 PM
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