| Research Topics: |
| INDEX |
| AI-chat 5 |
| PRIME 22 |
| aging 12 |
| brain 10 |
| brainwave 1 |
| cancer 8 |
| climate 2 |
| cognition 6 |
| covid-19 3 |
| crime 3 |
| culture 1 |
| dental 1 |
| diabetes 8 |
| disease 3 |
| economy 1 |
| genetics 8 |
| heart 5 |
| immune 5 |
| kidneys 5 |
| language 1 |
| metabolism 1 |
| misc 1 |
| nutrition 5 |
| pain 3 |
| physical 3 |
| politics 3 |
| pollution 1 |
| practice 3 |
| privacy 5 |
| psychology 8 |
| reproduction 4 |
| rights 2 |
| sleep 1 |
| unk |
| war-confl |
|
Scanned: 2683 Evaluated: 284 Selected: 75 |
| PRIME NUTRITION | |||||||||||||||||||
Aaa13-001 | The Science of Soy: A Comprehensive Review of Health Benefits and Clinical Evidence | ||||||||||||||||||
| Quote: | oybeans have been a dietary staple in East Asian cultures for millennia and are now a focal point of global nutritional science. As one of the few plant-based sources of complete protein, soy offers a unique profile of bioactive compounds, most notably isoflavones. This article examines the scientific consensus regarding the health benefits of soy, ranging from cardiovascular protection to cancer risk reduction and metabolic health. | ||||||||||||||||||
| Article: | https://richardgoldberg.substack.com/p/the-science-of-soy-a-comprehensive | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| PRIME CANCER | |||||||||||||||||||
Aaa13-002 | New dual drugs eliminate tumors when combined with immunotherapy | ||||||||||||||||||
| Quote: | Researchers at Johns Hopkins University and the University of Maryland School of Pharmacy have developed a set of novel, first-in-class drugs that inhibit hypoxia-inducible factors 1 and 2, a pair of transcription factors considered to be master regulators of cancer progression. The study, to be published April 2 in the Journal of Experimental Medicine JEM, shows that these drugs, when combined with immunotherapy, can completely eliminate breast, colorectal, melanoma, and prostate tumors in mice, suggesting that they could eventually be used to treat a broad range of cancers in humans. | ||||||||||||||||||
| Article: | https://www.news-medical.net/news/20260402/New-dual-drugs-eliminate-tumors-when-combined-with-immunotherapy.aspx | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| PRIME BRAIN CANCER NUTRITION | |||||||||||||||||||
Aaa13-005 | Aggressive brain cancer may respond to high-dose vitamin therapy, study suggests Majority of glioblastoma patients showed no disease progression after 6 months on vitamin B3 | ||||||||||||||||||
| Quote: | Niacin was found to restore function in weakened immune cells, improving their ability to target and destroy tumor cells. ... previous research has shown that vitamin B3 decreases inflammation and bolsters immune function. | ||||||||||||||||||
| Article: | https://www.foxnews.com/health/aggressive-brain-cancer-may-respond-high-dose-vitamin-therapy-study-suggests | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| PRIME BRAIN COGNITION IMMUNE NUTRITION | |||||||||||||||||||
Aaa13-006 | What Is Miracle Berry and How Does It Change Taste? Benefits, Uses, and Effects | ||||||||||||||||||
| Quote: | Accounting for about 50 of total free amino acids in the heart, taurine supports vascular health through its impact on blood pressure, cardiac contractility, and vascular function.3 These effects are thought to be mediated in part through modulation of intracellular calcium handling, osmoregulation, and mitochondrial homeostasis.1,3 Specifically, taurine promotes nitric oxide NO production and reduces endothelial dysfunction to mitigate inflammation, improve blood flow, and enhance vascular relaxation. ... Within the brain, taurine participates in calcium signaling, influencing neuron excitability and synaptic transmission. It also interacts with GABAergic and glycinergic systems, contributing to inhibitory neurotransmission.3 Overall, the neuromodulatory potential of taurine indicates its active role in cognitive processes, mood, behavior, memory, learning, and anxiety regulation. ... Taurine is also highly concentrated in the retina to protect it from oxidative stress. | ||||||||||||||||||
| Comment: | I notice cognitive and mood improvements when taking taurine. | ||||||||||||||||||
| Article: | Risks-Explained.aspxhttps://www.news-medical.net/health/Taurine-Deficiency-Symptoms-Causes-and-Health- https://www.news-medical.net/health/Taurine-Deficiency-Symptoms-Causes-and-Health-Risks-Explained.aspx | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| PRIME PRIVACY RIGHTS | |||||||||||||||||||
Aab13-006 | This Flock Camera Leak is like Neflix for Stalkers | ||||||||||||||||||
| Comment: | Witin minutes ha was able to find addresse4s, medical histories, police actions, etc. for the specific people he saw on these public surveilance cameras. | ||||||||||||||||||
| Article: | https://youtube.com/watch?v=vU1-uiUIHTo | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| PRIME DIABETES HEART | |||||||||||||||||||
Mcr13-014 | Retinal microvascular features are associated with CMR measures of subclinical cardiovascular dysfunction | ||||||||||||||||||
| Quote: | Background Microvascular dysfunction is a key component of many cardiovascular CV diseases. Assessing the retinal microvasculature through retinal imaging may therefore provide a window into evaluating a range of CV diseases. This study sought to generate hypotheses regarding relationships between different retinal microvascular features RVF and measures of subclinical CV dysfunction derived from cardiovascular magnetic resonance CMR imaging. ... Conclusions In a diabetic cohort, we identified novel and biologically plausible associations between RVF and CMR measures of subclinical CV dysfunction. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.26.26348318v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.26.26348318v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Cian Wade, Alicja R Rudnicka, Hana El Diwany, Charlotte Zheng, Ian Yeung, Robin D Hamilton, Masliza Mahmod, Helena B Thomaides Brears, Charlie Diamond, Ravi Pattanshetty, John Anderson, Ryan Chambers, Roshan A Welikala, Jiri Fajtl, Sarah A Barman, Elijah R Behr, Christopher G Owen, | ||||||||||||||||||
| PRIME DIABETES | |||||||||||||||||||
Mga13-004 | Genome-wide association and Mendelian randomization analyses link Helicobacter pylori infection to Human Leukocyte Antigen polymorphisms and autoimmune diseases. | ||||||||||||||||||
| Quote: | Mendelian randomization MR analysis revealed that genetic liability to H. pylori infection has both positive and negative causal relationships with a variety of diseases, including autoimmune-related diseases such as Type 1 diabetes, Hashimotos disease, atopic dermatitis, as well as traits like body height and weight. These genetic findings strongly support the notion that genetic liability to H. pylori infection influences not only gastrointestinal diseases, but also a broader spectrum of health issues, thereby providing valuable insights for public health strategies and personalized medicine approaches. | ||||||||||||||||||
| Comment: | It is not just ulcers that H. Pylori can cause. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.27.26349357v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.27.26349357v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | the+Tohoku+Medical+Megabank+Project+Study+Group,+span+class="nlm-collab"+data-hwp-id="collab-2">the+Biobank+Japan+Project&t=50" TARGET=auth>Tomoki Kyosaka, Akira Narita, Jerzy K Kulski, Aye Ko Ko Minn, Akimitsu Miyake, Yurii Kotsar, Kyoga Hiraide, Takafumi Ojima, Masahiro Nakatochi, Shinichi Namba, Taiki Yamaji, Yoichi Sutoh, Yu Sasaki, Linda Broer, Fabian Frost, Yuriko N. Koyanagi, Yumiko Kasugai, Hidemi Ito, Norie Sawada, Shiori Nakano, Sadao Suzuki, Asahi Hishida, Teruhide Koyama, Yoko Kubo, Takamitsu Funayama, Satoshi Makino, Matsuyuki Shirota, Jun Takayama, Chinatsu Gocho, Sachiyo Sugimoto, Yayoi Otsuka-Yamasaki, Kozo Tanno, Yasuhiko Abe, Osamu Nakajima, Manon C W Spaander, Stefan Weiss, Markus M. Lerch, Daniel Levy, Shih-Jen Hwang, Alexis C. Wood, Stephen S. Rich, Jerome I. Rotter, Kent D. Taylor, Russell P. Tracy, Hannah Stocker, Hermann Brenner, Marcis Leja, Raitis Peculis, Atsushi Hozawa, Kengo Kinoshita, Atsushi Shimizu, Masayuki Yamamoto, Keitaro Matsuo, Motoki Iwasaki, Kenji Wakai, Yoshiyuki Ueno, Gwenny Fuhler, Georg Homuth, Maikel P Peppelenbosch, Yukinori Okada, Shinichi Kuriyama, Motomichi Matsuzaki, Gen Tamiya, span class="nlm-collab" data-hwp-id="collab-1">the Tohoku Medical Megabank Project Study Group, span class="nlm-collab" data-hwp-id="collab-2">the Biobank Japan Project, | ||||||||||||||||||
| PRIME AGING COGNITION GENETICS | |||||||||||||||||||
Mge13-012 | Genetic and epigenetic regulation of SLC6A4 shapes vulnerability to cognitive decline and depressive tendency in later life | ||||||||||||||||||
| Quote: | DNA methylation at a functional promoter CpG site increased with age and partially mediated age-related cognitive decline specifically among low-activity genotypes. In contrast, the high-activity genotype was associated with relative resistance to these functional declines, partly mediated by a protective effect on hippocampal volume during aging. Notably, genotype-dependent effects on hippocampal volume were absent in adolescence, indicating that the influence of SLC6A4 emerges in an aging-specific manner. Together, these findings identify SLC6A4 promoter activity as a key genetic factor modulating vulnerability and resilience in later life. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.26.26349121v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.26.26349121v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | The+Japan+Prospective+Studies+Collaboration+for+Aging+and+Dementia+(JPSC-AD)+study+group&t=50" TARGET=auth>Yutaro Yanagida, Yutaka Nakachi, Naoto Kajitani, Satoshi Kikkawa, Tempei Ikegame, Shinsuke Koike, Norihide Maikusa, Naohiro Okada, Izumi Naka, Jun Ohashi, Hiroko Sugawara, Kazuhiro Yoshiura, Ayaka Fujii, Emi Kiyota, Risa Watanabe, Yui Murata, Yasuyuki Taki, Yasuko Tatewaki, Benjamin Thyreau, Yuji Takano, Manabu Makinodan, Norio Sakai, Tomohisa Ishikawa, Yosuke Hidaka, Mamoru Hashimoto, Yoshihiko Furuta, Tomoyuki Ohara, Toshiharu Ninomiya, Kiyoto Kasai, Minoru Takebayashi, Miki Bundo, Kazuya Iwamoto, span class="nlm-collab" data-hwp-id="collab-1">The Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) study group, | ||||||||||||||||||
| PRIME DISEASE GENETICS PRIVACY | |||||||||||||||||||
Mim13-002 | Utility of 3D Facial Analysis As A Biomarker In Rare Diseases Exploration with Hereditary Angioedema | ||||||||||||||||||
| Quote: | Importance Digital Phenotyping DP utilizes digital technologies to assess observable phenotypic traits, enhancing our understanding of various disease states. It aims to support equitable interventions through diverse digital data, fostering inclusivity by integrating various digital devices. | ||||||||||||||||||
| Comment: | Chinese stud4y, buiolt-in discrimination for social crediit scorekeeping, medical privacy violation, etc.. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.26.26349135v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.26.26349135v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Saumya Jamuar, Richard Palmer, Lee Haur Yueh, Faith Li-Ann Chia, Choo Beng Goh, Stuart Lee, Petra Helmholz, Shermaine Chan, Gareth Baynam, | ||||||||||||||||||
| PRIME COVID-19 DIABETES | |||||||||||||||||||
Min13-016 | A protocol for assessment of interventions using a computational phenotype for Long COVID | ||||||||||||||||||
| Quote: | All secondary outcomes were associated with the COVID group, when adjusted for multiplicity. Incident diagnoses with strong associations HR 2 included thromboembolism, hair loss, diabetes mellitus, obesity, and hypoxia. Anosmia/dysgeusia was associated with COVID, but wide confidence intervals reflected few charted diagnoses. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.26.26347671v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.26.26347671v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Amitabh Amitabh Gunjan, Lawrence Huang, Anudeep Appe, Paul A. McKelvey, Heather A. Algren, Mark Berry, Essy Mozaffari, Bill J. Wright, Jennifer J. Hadlock, Jason D. Goldman, | ||||||||||||||||||
| PRIME NUTRITION | |||||||||||||||||||
Mph13-022 | TTI-0102: A Novel Natural Controlled-Release Cysteamine Prodrug for Mitochondrial Disease and Cystinosis | ||||||||||||||||||
| Quote: | Conclusions This Phase 2 trial provides proof-of-concept that TTI-0102 is safe and well-tolerated in MELAS patients while treated with less than 65 mg/kg/day, with efficacy signals in fatigue reduction, a cardinal symptom affecting 71-100 of mitochondrial disease patients. The drugs tri-faceted mechanism through sustained cysteamine, taurine, and pantothenic acid delivery addresses oxidative stress, mitochondrial energy metabolism, and cofactor deficiency. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.26.26347968v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.26.26347968v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Patrice P Rioux, | ||||||||||||||||||
| PRIME PSYCHOLOGY | |||||||||||||||||||
Mpy13-022 | Sex Differences in PTSD Risk Among Autistic Individuals: A Population-Based Matched Cohort Study | ||||||||||||||||||
| Quote: | Conclusion: Autism is associated with substantially elevated PTSD risk, particularly among females with comorbid ADHD. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.03.31.26349863v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.03.31.26349863v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Shelby Smout, Seulgi Jung, Veerle Bergink, Behrang Mahjani, | ||||||||||||||||||
| AI-CHAT PRIME | |||||||||||||||||||
Zza13-001 | AI must foster maternal instincts or we risk extinction, warns Geoffrey Hinton | ||||||||||||||||||
| Quote: | Geoffrey Hinton, who many consider to be the godfather of artificial intelligence, says if AI continues to develop without appropriate guardrails, a worst-case scenario could lead to human extinction. ... Wheres an example of a more intelligent thing being controlled by a less intelligent thing? the best example I know of and perhaps the only one in the sense were talking about is how a baby controls a mother and thats because evolution built stuff into the mother. She cant bear the sound of the baby crying. She gets all sorts of hormonal rewards from being nice to the baby. It was very important, obviously, for evolution to let the baby control the mother for the survival of the species. | ||||||||||||||||||
| Article: | https://www.cbc.ca/radio/ideas/geoffrey-hinton-maternal-instincts-9.7094116 | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| AI-CHAT PRIME | |||||||||||||||||||
Zza13-003 | Stanford Study: Sycophantic AI Reinforces Bad Behavior 49 More than Humans | ||||||||||||||||||
| Quote: | The Stanford Report reports that a study published in the journal Science by researchers at Stanfords computer science department has uncovered troubling patterns in how AI models interact with users seeking advice on social and interpersonal matters. The research demonstrates that AI systems affirm users positions 49 percent more frequently than human respondents do on average, creating what experts warn could be harmful sycophants feedback loops that discourage personal accountability. ... The researchers discovered another unexpected finding: when study participants were asked to evaluate the objectivity of both types of AI responses, they rated sycophantic and non-sycophantic answers as equally objective. This suggests users may not recognize when AI is being excessively agreeable, making the bias particularly insidious. ... | ||||||||||||||||||
| Comment: | What do you expect? Their programmed goal is repeat business. You don't earn customer's trust by insulting them or presenting them with hard facts that contradict what a person wants to hear. And being oriented to find matching words and phrases, they will strongly tend toward confirmation bias, creating a mini-echo chamber supporting the customer's views. | ||||||||||||||||||
| Article: | https://www.breitbart.com/tech/2026/04/02/stanford-study-sycophantic-ai-reinforces-bad-behavior-49-more-than-humans/ | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| PRIME WAR-CONFL | |||||||||||||||||||
Zza13-004 | Report: FBI Investigates China-Linked Hack of U.S. Surveillance as Major Cyber Incident | ||||||||||||||||||
| Quote: | The FBI notified Congress in early March that it was investigating suspicious activities on one of its sensitive internal computer networks, upon which the Bureau stored information related to wiretaps and other surveillance programs. The intrusion was first detected on February 17 and, by all accounts, the FBIs cybersecurity team was able to shut it down fairly quickly. ... The FBI told Congress the attackers got into their system by leveraging infrastructure from a commercial Internet service provider, a third-party attack strategy that has become increasingly popular with threat actors for penetrating high-security systems. | ||||||||||||||||||
| Article: | https://www.breitbart.com/national-security/2026/04/02/report-fbi-investigates-china-linked-hack-of-u-s-surveillance-as-major-cyber-incident/ | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| PRIME AGING COGNITION | |||||||||||||||||||
Zzb13-000 | Is Methylene Blue the Secret Weapon for Fighting Alzheimers and Keeping Your Brain Young? | ||||||||||||||||||
| Comment: | Works for some peoople, others say they have not had much success with it. there are some interesting youtube videos on the subject. | ||||||||||||||||||
| Article: | https://www.thegatewaypundit.com/2026/03/is-methylene-blue-secret-weapon-fighting-alzheimers-keeping-17/ | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| PRIME CLIMATE | |||||||||||||||||||
Zzb13-001 | The Sun And Water Vapour Drive Climatic Changes, Not CO2 | ||||||||||||||||||
| Quote: | Using widely accepted global temperature, specific humidity, solar activity, and albedo cloud datasets, Ato has reaffirmed the now-common conclusion Koutsoyiannis, 2024; Berry, 2023; Nikolov and Zeller, 2024; Grabyan, 2025; Soon et al., 2023; Ato, 2024 that absorbed shortwave radiation forcing via cloud albedo changes and variations in solar activity are driving modern global warming. ... The sequence of influence on Earths climate is as follows: solar activity and albedo determine Earths SST and air temperature, and SST then exclusively determines G-SpHm global specific humidity/water vapor concentrations. Compared to these two indicators ASW and TSI, the influence of atmospheric CO2 was confirmed to be effectively negligible. | ||||||||||||||||||
| Article: | https://principia-scientific.com/the-sun-and-water-vapour-drive-climatic-changes-not-co2/ | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| PRIME CRIME POLITICS | |||||||||||||||||||
Zzb13-002 | Republic of Somaliland Asks U.S. to Extradite Ilhan Omar There to Face Justice | ||||||||||||||||||
| Quote: | Speaking of which, Vance connected Omar not only to immigration fraud, of which her marriage to her brother is a part, but also to fraudulent networks pulling in taxpayer dollars here in America. She has been at the center of a lot of the worst fraudsters in the Somalian community, he argued. The Republic of Somaliland wants independence from Somalia precisely because of the sort of violence and corruption that the people who control Somalia and move to the USA from Somalia perpetrate. | ||||||||||||||||||
| Article: | https://pjmedia.com/catherinesalgado/2026/03/28/republic-of-somaliland-asks-us-to-extradite-ilhan-omar-there-to-face-justice-n4951173 | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| PRIME CLIMATE | |||||||||||||||||||
Zzb13-006 | How One Good Volcano Can Cancel Years of Climate Claims | ||||||||||||||||||
| Quote: | of those readings once introduced into the global processing pipeline. Raw observations from CR-VOLC-EL-INFIERNO-01 indicate sustained daily maximum temperatures exceeding 300C over multiple reporting intervals. Such values would ordinarily trigger immediate exclusion under standard quality control thresholds. Yet archival flags associated with this station indicate no such exclusion occurred. Instead, the readings were retained and subjected to standard homogenization procedures. ... In the standard reconstruction, global mean temperature anomalies show an increase of approximately 0.9C from 1975 to present. In the modified reconstruction, the increase is reduced to approximately 0.02C over the same period. | ||||||||||||||||||
| Article: | https://redstate.com/wardclark/2026/04/01/how-one-good-volcano-can-cancel-years-of-climate-claims-n2200867 | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| PRIME PRIVACY RIGHTS | |||||||||||||||||||
Zzb13-007 | Make your computer your property again | ||||||||||||||||||
| Comment: | HOw to stop Microsoft from spying on you in Windows 11. The better way is to use Linux. | ||||||||||||||||||
| Article: | http://youtube.com/watch/vmfg7h5t0Kwg | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| PRIME POLLUTION PSYCHOLOGY | |||||||||||||||||||
Zzb13-008 | Bisphenol a exposure and major depressive disorder: an integrative analysis combining network toxicology, molecular docking, genetic epidemiology, and transcriptomic validation | ||||||||||||||||||
| Quote: | A total of 571 shared targets between BPA and MDD were identified, enriched in pathways related to neurodevelopment, synaptic plasticity, and cognitive function. Six core targets ESR1, SRC, EGFR, AKT1, PLCG2, and JAK3 were highlighted. MR and SMR analyses supported causal roles for AKT1, SRC, PLCG2, and JAK3 in MDD, whereas EGFR exhibited a protective effect. These findings provide integrative evidence for molecular mechanisms underlying BPA-associated susceptibility to MDD and identify potential targets for future therapeutic intervention. | ||||||||||||||||||
| Article: | https://www.nature.com/articles/s41398-026-03862-5 | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Words: |
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Javilk's Research Links for Week 13 Updated 04/04/2026-01:13:07 AM What interests you? What have you found? Tell me! Drop me a note to subscribe or submit something. |