Research
Topics:
INDEX
AI-chat 5
PRIME 22
aging 12
brain 10
brainwave 1
cancer 8
climate 2
cognition 6
covid-19 3
crime 3
culture 1
dental 1
diabetes 8
disease 3
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misc 1
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practice 3
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unk
war-confl
 
Scanned: 2683
Evaluated: 284
Selected: 75

 
    PRIME    BRAIN    CANCER    NUTRITION   

Aaa13-005

Aggressive brain cancer may respond to high-dose vitamin therapy, study suggests Majority of glioblastoma patients showed no disease progression after 6 months on vitamin B3

Quote:Niacin was found to restore function in weakened immune cells, improving their ability to target and destroy tumor cells. ... previous research has shown that vitamin B3 decreases inflammation and bolsters immune function.
Article: https://www.foxnews.com/health/aggressive-brain-cancer-may-respond-high-dose-vitamin-therapy-study-suggests
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    PRIME    BRAIN    COGNITION    IMMUNE    NUTRITION   

Aaa13-006

What Is Miracle Berry and How Does It Change Taste? Benefits, Uses, and Effects

Quote:Accounting for about 50 of total free amino acids in the heart, taurine supports vascular health through its impact on blood pressure, cardiac contractility, and vascular function.3 These effects are thought to be mediated in part through modulation of intracellular calcium handling, osmoregulation, and mitochondrial homeostasis.1,3 Specifically, taurine promotes nitric oxide NO production and reduces endothelial dysfunction to mitigate inflammation, improve blood flow, and enhance vascular relaxation. ... Within the brain, taurine participates in calcium signaling, influencing neuron excitability and synaptic transmission. It also interacts with GABAergic and glycinergic systems, contributing to inhibitory neurotransmission.3 Overall, the neuromodulatory potential of taurine indicates its active role in cognitive processes, mood, behavior, memory, learning, and anxiety regulation. ... Taurine is also highly concentrated in the retina to protect it from oxidative stress.
Comment: I notice cognitive and mood improvements when taking taurine.
Article: Risks-Explained.aspxhttps://www.news-medical.net/health/Taurine-Deficiency-Symptoms-Causes-and-Health- https://www.news-medical.net/health/Taurine-Deficiency-Symptoms-Causes-and-Health-Risks-Explained.aspx
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    BRAIN    CANCER    IMMUNE   

Mca13-024

A circulating protein signature for predicting severe immune-related adverse events following CAR T-cell therapy in relapsed/refractory lymphoma

Quote:The protein biomarker panels provide a means to risk stratify patients who are at high risk for developing severe CRS and ICANS, to inform on the need for prophylactic interventions and improve patient outcomes.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.29.26349664v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.29.26349664v1.full-text
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Search Authors: Ehsan Irajizad, Johannes Francois Fahrmann, Hiroyuki Katayama, Paolo Strati, Ranjit Nair, Michael Wang, Dai Chihara, Luis Fayad, Sairah Ahmed, Swaminathan P Iyer, Frederick L Locke, Marco Davila, Christopher Flowers, Elizabeth Shpall, Sattva Neelapu, Samir Hanash, Jason Westin, Michael D Jain, Teny M John, Neeraj Y Saini, 
Search Words:
mmune effector cell-associated neurotoxicity syndrome ICANS Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
cytokine release syndrome CRS Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    BRAIN   

Mne13-008

Microstructural white matter disruptions and their clinical correlates in Wilson disease: A neurite orientation dispersion and density imaging study

Abstract: https://www.medrxiv.org/content/10.64898/2026.03.27.26349503v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.27.26349503v1.full-text
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Search Authors: Ann Carolin Hausmann, Silja K. Querbach, Christian Rubbert, Alfons Schnitzler, Julian Caspers, Christian Johannes Hartmann, 
    AGING    BRAIN   

Mne13-012

Predicting long term clinical outcomes in Parkinsons Disease using short term rating scales

Quote:Conclusions: We have demonstrated how a treatment effect in a trial specified in terms of a progression change of a rating scale can be contextualised into a long-term reduction in the probability of clinically relevant milestones.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.27.26349548v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.27.26349548v1.full-text
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Search Authors: Matthew Burnell, Cristina Gonzalez-Robles, Marie-Louise Zeissler, Michele Bartlett, Caroline S Clarke, Carl Counsell, Michele T Hu, Tom Foltynie, Camille Carroll, Michael Lawton, Yoav Ben-Shlomo, James Carpenter, 
    AGING    BRAIN   

Mne13-018

Plasma pTau217 as a Prognostic, Monitoring, and Risk-Stratification Biomarker of Clinical Progression in Lewy Body Disease

Abstract: https://www.medrxiv.org/content/10.64898/2026.03.26.26349399v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.26.26349399v1.full-text
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Search Authors: S. A. Lorkiewicz, C. Abdelnour, M. Bolen, A. M. Smith, M. Shahid-Besanti, D. Hemachandra, E. M. Müller-Oehring, N. Siddiqui, L. Montoliu-Gaya, B. Arslan, N. J. Ashton, E. N. Wilson, L. Tian, K. I. Andreasson, E. C. Mormino, V. W. Henderson, H. Zetterberg, K. L Poston, 
    AGING    BRAIN   

Mne13-022

Abnormalities in core AD biomarkers precede inflammatory and glial markers in CSF in Autosomal Dominant Alzheimers Disease

Quote:INTERPRETATION: Our results suggest that the main CSF proteomic landscape changes in ADAD are due to the presence of a pathogenic mutation and occur prior to symptom onset. Improved performance of multi-protein composite to predict EYO compared to single biomarker values highlights the added value of multiplex proteomic signatures for biomarker panel development.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.31.26349851v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.31.26349851v1.full-text
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Search Authors: Wenjing Lin, Aleksandra Beric, Julie K Wisch, Bryce Baker, Gina Jerome, Matthew Minton, Sam Preminger, Jennifer Stauber, Suzanne E Schindler, Jeff Dage, Ricardo Allegri, David Aguillon, Tammie Benzinger, Jasmeer Chhatwal, Alisha Daniels, Gregory Day, Emma Devenney, Nick Fox, Alison Goate, Brian Gordon, Jason Hassenstab, Edward Huey, Takeshi Ikeuchi, Suman Jayadev, Mathias Jucker, Takanobu Ishiguro, Jae-Hong Lee, Allan Levey, Johannes Levin, John C Morris, Richard Perrin, Alan Renton, Jee Hoon Roh, Chengjie Xiong, Randall J Bateman, Beau Ances, Carlos Cruchaga, Celeste Karch, Charlene Supnet-Bell, Jorge J Llibre-Guerra, Eric McDade, Laura Ibanez, 
    AGING    BRAIN   

Mne13-024

NeuroFM: Toward Precision Neuroimaging with Foundation Models for Individualized Brain Health Estimation

Quote:Evaluated on 136,361 multi-cohort volumes, NeuroFM generalizes across domains and enables individual-level brain health profiling, estimating future dementia risk years before diagnosis. Together, these findings establish a disease-naive foundation model for precision neuroimaging with potential to support quantitative brain health assessments across settings.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.27.26349489v2
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.27.26349489v2.full-text
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Search Authors: Austin Dibble, Connor Dalby, Michele Sevegnani, Alessio Fracasso, Donald M Lyall, Monika Harvey, Michele Svanera, 
    BRAIN    KIDNEYS   

Mne13-038

The dynamics of glutamate receptor subunit GluN1 concentration in urinary astrocyte-derived extracellular vesicles from a patient with anti-NMDAR encephalitis

Quote:We investigated whether urinary astrocyte-derived extracellular vesicles ADEVs could serve as a non-invasive proxy for brain receptor dynamics.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.30.26349276v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.30.26349276v1.full-text
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Search Authors: Junhua Mei, Mian-mian Chen, Qing Yang, Shu-xian Xu, Chao Wang, Honggang Lyu, Qian Gong, Zhongchun Liu, Edward Bullmore, Mary-Ellen Lynall, Xinhui Xie, 
    BRAIN    COGNITION   

Mpy13-018

The exposome and attention-related brain networks jointly predict attention problems in early adolescence

Quote:Conclusion Interactions between environmental exposures, experiences, and brain network organization are associated with attention problems in early adolescence. These findings support a bidirectional framework linking the environment and functional brain networks in the development of attention problems.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.26.26349404v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.26.26349404v1.full-text
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Search Authors: Nia Berrian, Arielle S Keller, Alfred F. Chao, Andrew J. Stier, Tyler M Moore, Ran Barzilay, Marc G. Berman, Omid Kardan, Monica D. Rosenberg, 

  Javilk's Research Links for Week 13
Updated 04/04/2026-01:13:07 AM
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