| Research Topics: |
| INDEX |
| AI-chat 1 |
| PRIME 11 |
| aging 12 |
| body 1 |
| brain 14 |
| brainwave 1 |
| cancer 11 |
| climate 1 |
| cognition 4 |
| covid-19 2 |
| culture 6 |
| dental 6 |
| diabetes 9 |
| disease 1 |
| emergency 1 |
| energy 1 |
| eyes 1 |
| genetics 4 |
| gut 2 |
| heart 8 |
| herbs 1 |
| immune 2 |
| kidneys 3 |
| lungs 2 |
| metabolism 3 |
| microbiome 4 |
| nutrition 6 |
| obesity 3 |
| pain 1 |
| politics 4 |
| pollution 4 |
| psychology 9 |
| radiation 1 |
| religion 1 |
| rights 1 |
| unk |
| virus 3 |
| war-confl |
|
Scanned: 1397 Evaluated: 447 Selected: 78 |
| BRAIN GENETICS | |||||||||||||||||||
Mge17-018 | Duplication within 14q32.13 implicates a chimeric CLMN::SYNE3 RNA transcript in cerebellar ataxia | ||||||||||||||||||
| Quote: | Our data suggests that ectopic expression of SYNE3 in cerebellar Purkyn#283; neurons, mediated by the CLMN promoter, leads to cerebellar atrophy and causes spinocerebellar ataxia in the SCA30 family. This is an example of Mendelian disease arising from a novel, chimeric transcript with a likely dominant negative effect. Chimeric transcripts are commonly associated with cancers, but they are not often associated with monogenic disorders. Detection of chimeric transcripts as part of structural variant analysis could increase the genetic diagnostic yield of Mendelian disorders. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.04.23.26350376v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.04.23.26350376v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Thomas M Litster Robert A Wilcox Rene Carroll Alison E Gardner Nazzmer M Nazri Cheryl A Shoubridge Martin B Delatycki Katja Lohmann Marc Agzarian Rafaela Turella Divani Haloom Rafehi Liam Scott Gavin Monahan Phillipa J Lamont Catherine Ashton Nigel G Laing Gianina Ravenscroft Melanie Bahlo Eric Haan Paul J Lockhart Kathryn L Friend Mark A Corbett Jozef Gecz, | ||||||||||||||||||
| AGING BRAIN COGNITION | |||||||||||||||||||
Mge17-020 | Behavioral and psychological symptoms of dementia: insights from a multivariate and network-based brain proteome-wide study | ||||||||||||||||||
| Quote: | Behavioral and psychological symptoms of dementia (BPSD) are common, profoundly troubling to patients and caregivers, and difficult to treat, yet their molecular underpinnings remain poorly understood. Here, we generated a large brain proteomic dataset with nine BPSD domains assessed in life from 376 donors from three cohorts. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.04.23.26351110v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.04.23.26351110v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Selina M. Vattathil Duc M. Duong Marla Gearing Nicholas T. Seyfried Robert S. Wilson David A. Bennett Randall L. Woltjer Thomas S. Wingo Aliza P. Wingo, | ||||||||||||||||||
| AGING BRAIN | |||||||||||||||||||
Mne17-002 | Spatiotemporal Tau Accumulation and Its Clinical Impact on PSP: Longitudinal Florzolotau (18F) PET | ||||||||||||||||||
| Quote: | Conclusions This study provides in vivo evidence of the spatiotemporal progression of tau pathology in PSP. In the GP, tau accumulation emerges early and continues to rise with clinical deterioration. These findings support the utility of florzolotau PET for monitoring disease progression and as a biological outcome measure in tau-targeted therapeutic trials. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.04.26.26350467v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.04.26.26350467v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Yoshikazu Chishiki Kenji Tagai Yuko Kataoka Ryoji Goto Kenta Osawa Asaka Oyama Hideki Matsumoto Masanori Ichihashi Yuki Momota Tetsuji Kamada Chie Seki Kiwamu Matsuoka Kosei Hirata Shin Kurose Sho Moriguchi Yuki Komatsu Hideo Kato Yasuharu Yamamoto Yoshikazu Nakano Shigeki Hirano Hitoshi Shinotoh Hitoshi Shimada Tokahiko Tokuda Kazunori Kawamura Ming-Rong Zhang Keisuke Takahata Makoto Higuchi Hironobu Endo, | ||||||||||||||||||
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| BRAIN PSYCHOLOGY | |||||||||||||||||||
Mne17-004 | Effects of transcranial direct current stimulation (tDCS) combined with cognitive therapy in individuals with cognitive impairment: a systematic review and meta-analysis | ||||||||||||||||||
| Quote: | Conclusion tDCS combined with cognitive training may provide a small, short-term benefit for cognitive function, but high heterogeneity across studies and loss of effect at follow-up underscore the need for larger, better-standardized trials to clarify its clinical value. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.04.26.26351755v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.04.26.26351755v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Patricio Soto-Fernndez Lilian Toledo-Rodrguez Alejandra Figueroa-Vargas Paulo Figueroa-Taiba Pablo Billeke, | ||||||||||||||||||
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| AGING BRAIN PSYCHOLOGY | |||||||||||||||||||
Mne17-008 | BETA: Resting-state fMRI Biotypes for tDCS Efficacy in Anxiety Among Older Adults At Risk For Alzheimers Disease | ||||||||||||||||||
| Quote: | . Crucially, one cluster is resistant to frontal-lobe tDCS, whereas two clusters demonstrate significant anxiety reduction following stimulation. The responsive subtypes are defined by strengthened connectivity between the lateral occipital cortex-superior division (sLOC) and medial frontal cortex (MedFC), and between sLOC and the intracalcarine cortex (ICC). | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.04.24.26351493v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.04.24.26351493v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Skylar E. Stolte Junfu Cheng Chintan Acharya Lin Gu Andrew OShea Aprinda Indahlastari Adam J. Woods Ruogu Fang, | ||||||||||||||||||
| BRAIN | |||||||||||||||||||
Mne17-010 | Linking Network Damage to Post-Stroke Depression: A Neurotransmitter-Informed Connectome Analysis | ||||||||||||||||||
| Quote: | Damage to networks related to the serotonin transporter (5-HTT) and the vesicular acetylcholine transporter (VAChT) was independently associated with increased odds of PSDS in covariate-adjusted models and improved model fit beyond clinical and lesion-based predictors. In contrast, associations with other NT systems, including dopaminergic networks, were not consistently implicated across cohorts. These findings identify the serotonergic and cholinergic network architecture as a key neurochemical substrate that modulates vulnerability to PSDS. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.04.24.26351561v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.04.24.26351561v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Benedikt M. Frey Julian Klingbeil Margaret Jane Moore Philipp J. Koch Jan Feldheim Tom Hornberger Gtz Thomalla Tim Magnus Fanny Quandt Nele Demeyere Dorothee Saur Robert Schulz, | ||||||||||||||||||
| AGING BRAIN BRAINWAVE | |||||||||||||||||||
Mne17-016 | Targeted memory reactivation during sleep modulates spindle and slow wave density, but not motor memory consolidation, in Parkinsons disease | ||||||||||||||||||
| Quote: | Results showed no effect of TMR on motor retention or dual-tasking, with no difference between the groups. However, the TMR intervention did increase slow-wave density and decreased spindle density in both groups, and slow-wave amplitude during the presentation of the auditory cues was positively associated with performance in HOA. In conclusion, TMR applied during a 2 hour nap did not enhance motor retention, but the changes in sleep physiological features could be linked to a possible underlying effect on memory processing that warrants further investigation. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.04.22.26351552v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.04.22.26351552v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Letizia Micca Genevieve Albouy Bradley R King Alice Nieuwboer Wim Vandenberghe Pascal Borze Bertien Buyse Dries Testelman Judith Nicolas Moran Gilat, | ||||||||||||||||||
| BRAIN | |||||||||||||||||||
Mot17-002 | Repolarisation Speed May Vary with Characteristic Frequency in Human Spiral Ganglion Cells: Preliminary Observation from Electrically Evoked Compound Action Potentials | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.04.23.26351590v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.04.23.26351590v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Jason T.H. Lien Stefan Strahl Charlotte Garcia Deborah Vickers, | ||||||||||||||||||
| BRAIN CANCER GENETICS | |||||||||||||||||||
Mpt17-004 | Whole-Genome Long-Read Sequencing for Rapid Comprehensive Molecular Diagnostics of Brain Tumors | ||||||||||||||||||
| Quote: | Conclusions Nanopore WGS delivers comprehensive genetic and epigenetic results with a fast turn-around compared to standard methods. This enables efficient, accurate, and scalable molecular diagnostics of CNS tumors using a single platform. Its broad applicability supports its implementation in routine clinical practice and may be extended to other cancer types requiring complex genomic profiling. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.04.23.26351563v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.04.23.26351563v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Skarphinn Halldorsson Richard Mark Nagymihaly Christian Domilongo Bope Marius Lund-Iversen Pitt Niehusmann Thomas Lien-Dahl Jens Pahnke Thomas Brning Geir Kongelf Areeba Patel Felix Sahm Philipp Euskirchen Henning Leske Einar Osland Vik-Mo, | ||||||||||||||||||
| BRAIN PSYCHOLOGY | |||||||||||||||||||
Mpy17-012 | Individualized cortical gradient and network topology reveal symptom-linked disruptions and neurobiological subtypes in schizophrenia | ||||||||||||||||||
| Quote: | Brain-symptom association analyses identified a latent dimension linking disorganization symptoms to topological alterations. Finally, clustering cortical alterations identified two robust subtypes, characterized by divergent anterior cingulate (S1) versus temporoparietal (S2) thickness differences aligned with the intrinsic gradient-topology patterns. Both subtypes were present early in the illness and stable across disease stages and age groups. These findings reveal systematic disruptions of cortical organization in schizophrenia, providing a network-level framework for macroscale brain organization and inter-individual heterogeneity. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.04.25.26351736v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.04.25.26351736v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Bin Wan Sara Larivire Clara A. Moreau Varun Warrier Richard A.I. Bethlehem Yun-Shuang Fan Yuankai He Ingrid Agartz Stener Nerland Erik G. Jnsson Derin Cobia Lei Wang Benedicto Crespo Facorro Rafael Romero-Garcia Patricia Segura Nerisa Banaj Daniela Vecchio Tamsyn Van Rheenen Philip James Sumner Elysha Ringin Susan Rossell Sean Carruthers Philip J. Sumner Will Woods Matthew Hughes Gary Donohoe Emma Corley Ulrich Schall Frans Henskens Rodney Scott Patricia Michie Carmel Loughland Paul Rasser Murray Cairns Bryan Mowry Stanley Catts Christos Pantelis Aristotle Voineskos Erin Dickie Henk Temmingh Freda Scheffler Oliver Gruber Rosanne Picotin Vince D. Calhoun Kyle M. Jensen Filip paniel David Tomecek Raymond Salvador Andriana Karuk Edith Pomarol-Clotet Tilo Kircher Lea Teutenberg Frederike Stein Udo Dannlowski Dominik Grotegerd Tiana Borgers Tim Hahn Rebekka Lencer Carlos Lpez-Jaramillo Melissa Green Yann Quide Vaughan Carr Stefan Ehrlich Peter Kochunov Christian Sorg Melissa Thalhammer David Glahn Amanda Rodrigue Kang Sim Ali Saffet Gonul Aslihan Uyar Demir Nicolas Crossley Alfonso Gonzalez-Valderrama Philipp Homan Wolfgang Omlor Giacomo Cecere Felice Iasevoli Giuseppe Pontillo Raquel Gur Ruben C. Gur Kosha Ruparel Theodore D. Satterthwaite Scott Sponheim Caroline Demro Young Chul Chung Soyolsaikhan Odkhuu Albert Yang I-Jou Chi Ole Andreassen Lars T. Westlye Unn K. H. Haukvik Nadine Parker Jakub Kopal Dag Alnaes Jaroslav Rokicki Carl M Sellgren Maria Lee Stefan Borgwardt Mihai Avram Taeyoung Lee Hang Joon Jo Irina Lebedeva Alexander Tomyshev Stefan Kaiser Paul M. Thompson Theo G. M. van Erp Jessica A. Turner Boris C. Bernhardt Sofie L. Valk Matthias Kirschner, | ||||||||||||||||||
| BRAIN NUTRITION | |||||||||||||||||||
Sda171-013 | Fish Oil May Be Hurting Your Brain, New Study Finds Diet and Weight Loss Nutrition Diseases and Conditions | ||||||||||||||||||
| Quote: | Fish oil has long been praised as brain-boosting, but new research suggests the story may be more complicated. Scientists found that in people with repeated mild head injuries, a key omega-3 fatty acid in fish oilEPAmay actually interfere with the brains ability to repair itself. Instead of helping recovery, it appears to weaken blood vessel stability, disrupt healing signals, and even ... | ||||||||||||||||||
| Article: | https://www.sciencedaily.com/releases/2026/04/260426012303.htm | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| BRAIN DIABETES GUT MICROBIOME NUTRITION PSYCHOLOGY | |||||||||||||||||||
Sda171-014 | Harvard Scientists Link Gut Bacteria to Depression Through Hidden Inflammation Trigger Diabetes Diet and Weight Loss Diseases and Conditions | ||||||||||||||||||
| Quote: | A gut bacterium may be quietly fueling depression through an unexpected chemical twist. Researchers found that when Morganella morganii interacts with a common pollutant, it produces a molecule that triggers inflammationsomething strongly linked to depression. This finding helps explain how gut microbes can influence brain health at a molecular ... | ||||||||||||||||||
| Article: | https://www.sciencedaily.com/releases/2026/04/260425091216.htm | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| AGING BRAIN | |||||||||||||||||||
Sda171-016 | These 80-Year-Olds Have the Memory of 50-Year-Olds. Scientists Now Know Why Dementia Personalized Medicine Intelligence | ||||||||||||||||||
| Quote: | A rare group of adults over 80, known as SuperAgers, are rewriting what we thought was possible for the aging brain. With memory abilities comparable to people decades younger, their brains either resist or withstand the damage typically linked to Alzheimers disease. Decades of research reveal that their social lifestyles and unique brain biology may hold the key to preserving cognitive ... | ||||||||||||||||||
| Article: | https://www.sciencedaily.com/releases/2026/04/260423022006.htm | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| BRAIN | |||||||||||||||||||
Sda172-004 | Your Dreams Arent Random. Heres Whats Really Happening | ||||||||||||||||||
| Quote: | Dreams are more structured than they seem, shaped by both personal traits and real-world experiences. Researchers found that the brain doesnt just replay daily lifeit reshapes it into imaginative, sometimes surreal scenarios. People who ... | ||||||||||||||||||
| Article: | https://www.sciencedaily.com/releases/2026/04/260428045538.htm | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
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Javilk's Research Links for Week 17 Updated 05/02/2026-01:34:02 AM What interests you? What have you found? Tell me! Drop me a note to subscribe or submit something. |