Research
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Scanned: 1397
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    COGNITION    OBESITY    PSYCHOLOGY   

Mdb17-012

Longitudinal Central Adiposity Accumulation is Associated with Cortical Alteration and Impaired Cognitive Function in Adolescents

Quote: The study reveals that central fat (BRI/WHtR) is closely linked to neurocognitive risks, and longitudinal fat accumulationrather than baseline adipositydrives cortical alteration. Notably, fat reduction activated adaptive neural change in obese adolescents, underscoring the importance of weigh regulation during neurodevelopment.
Abstract: https://www.medrxiv.org/content/10.64898/2026.04.22.26351453v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.04.22.26351453v1.full-text
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Search Authors: Lingxuan Zhang Bowen Qiu Zhifan Chen Xinyi Xu Ruoke Zhao Yiwei Chen Chenglin Ning Ruike Chen Mingyang Li Dan Wang Junfen Fu Dan Wu, 
    AGING    BRAIN    COGNITION   

Mge17-020

Behavioral and psychological symptoms of dementia: insights from a multivariate and network-based brain proteome-wide study

Quote: Behavioral and psychological symptoms of dementia (BPSD) are common, profoundly troubling to patients and caregivers, and difficult to treat, yet their molecular underpinnings remain poorly understood. Here, we generated a large brain proteomic dataset with nine BPSD domains assessed in life from 376 donors from three cohorts.
Abstract: https://www.medrxiv.org/content/10.64898/2026.04.23.26351110v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.04.23.26351110v1.full-text
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Search Authors: Selina M. Vattathil Duc M. Duong Marla Gearing Nicholas T. Seyfried Robert S. Wilson David A. Bennett Randall L. Woltjer Thomas S. Wingo Aliza P. Wingo, 
    COGNITION    HEART   

Mgr17-002

Pulse-wave harmonic signatures of cardiovascular regulatory coherence to a cognitive challenge in mild cognitive impairment: a community-based cross-sectional study

Quote: To evaluate whether hemodynamic responses to acute cognitive stress, measured via pulse-wave harmonic analysis, can characterize cardiovascular regulatory coherence and differentiate older adults with mild cognitive impairment (MCI) from cognitively intact individuals, this exploratory cross-sectional observational study utilized a within-session prepost cognitive task design.
Abstract: https://www.medrxiv.org/content/10.64898/2026.04.24.26351647v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.04.24.26351647v1.full-text
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Search Authors: Kun-Yuan Hsiao, 
    AGING    COGNITION   

Sda171-043

Doing This Throughout Life May Cut Alzheimers Risk by 38 Dementia Social Psychology Alzheimers

Quote: A lifetime of mental stimulationlike reading, writing, and learning new skillsmay help protect the brain as we age. People with the highest levels of cognitive enrichment had a much lower risk of Alzheimers and experienced symptoms years later than those with the lowest ...
Article: https://www.sciencedaily.com/releases/2026/04/260414075648.htm
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  Javilk's Research Links for Week 17
Updated 05/02/2026-01:34:02 AM
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