Research
Topics:
INDEX
MCS 3
PRIME 37
aging 18
brain 25
brainwave 4
cancer 20
climate 1
cognition 12
covid-19 3
crime 4
culture 4
dental 7
diabetes 7
diagnostics 4
disease 2
drugs 5
economy 2
exercise 2
eyes 1
genetics 7
gut 2
heart 11
immune 4
kidneys 2
language 3
lungs 2
metabolism 4
microbiome 4
misc 1
music 1
nutrition 16
obesity 2
pain 6
physical 1
politics 5
pollution 2
practice 2
privacy 2
psychology 12
reproduction 4
rights 1
sleep 5
soc-media
stress 1
tech 3
unk
vaccine 2
virus 2
war-confl
 
Scanned: 4202
Evaluated: 821
Selected: 129

 
    CANCER    NUTRITION   

Aaa25-004

A common vitamin could help fight one of the deadliest brain cancers.

Quote: A clinical trial is exploring whether high doses of vitamin B3 could give patients with glioblastoma a better chance against the aggressive brain cancer. Scientists found that niacin may help revive immune cells that tumors shut down, allowing them to attack cancer more effectively. Early results have been promising, with patients showing significantly better progression-free survival than expected.
Article: http://www.sciencedaily.com/releases/2026/06/260622014313.htm
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    CANCER   

Bcb25-002

R-CHOP in B cell non-Hodgkin lymphoma: balancing anti-tumor efficacy and NK-cell functionality

Article: https://www.biorxiv.org/content/10.64898/2026.01.12.698321v2
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Search Authors: Johanna Jansky Hannah Breitung Sylvia Zphel Laetitia Dngi Florian Wentzel Daniel Picard Nadja Kchler Hermann Eichler Marc Remke Moritz Bewarder Lorenz Thurner Gebhard Stopper Eva C Schwarz Markus Hoth, 
    CANCER   

Bcb25-003

The impact of normal tissue density on tumor growth and evolution in a 3D whole-tumor model of lung cancer

Article: https://www.biorxiv.org/content/10.1101/2025.09.25.676637v2
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Search Authors: Rafael R Bravo Mark Robertson-Tessi Scott Antonia Jhanelle Gray Amer Beg Robert Gatenby Matthew B. Schabath Alexander R A Anderson, 
    CANCER   

Bcb25-004

A generative reference grammar of healthy TCR repertoires reveals cancer-associated immune remodeling

Article: https://www.biorxiv.org/content/10.64898/2026.04.29.721631v2
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Search Authors: Archana Balan Yuval Elhanati Kevin E. Meza Landeros Marcus De Almeida Mendes Jiaying Lai Syed Shujaat Ali Zaidi Mesut Unal Betty Y.S. Kim Calixto-Hope G. Lucas Emerenziana Runco Vinay K. Puduvalli Jennifer Gantchev Charles A. Whittaker Pratibha Sharma Viviane Tabar Michael J. Cima Gerard Baquer David A. Reardon Alexei Stortchevoi Adrienne Boire Linghua Wang Forest M. White Dimitrios N. Sidiropoulos Kenny Kwok Hei Yu E. Antonio Chiocca Valsamo Anagnostou span classnlm-collab data-hwp-idcollab-1Data Science TeamLab span classnlm-collab data-hwp-idcollab-2Accelerating GBM Therapies TeamLab Rachel Karchin, 
    CANCER   

Bcb25-005

Differential response to LSD1 inhibition in prostate cancer reveals a YAP1 vulnerability in the neuroendocrine subtype

Article: https://www.biorxiv.org/content/10.1101/2024.01.17.576106v2
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Search Authors: SM Jasim R Kumar S Kim TEG Krueger IM Coleman SL Dalrymple L Antony DM Rosen B Hanratty RA Patel PS Nelson Z Aghaei JH Beumer MC Haffner TL Lotan A Mandl MA Carducci S Kachhap JT Isaacs SR Denmeade HY Rienhoff span classnlm-suffixJr. LA Sena WN Brennen, 
    CANCER   

Bcb25-006

Refined USP25/28 inhibitors with enhanced selectivity towards c-Myc driven squamous lung cancer cells

Article: https://www.biorxiv.org/content/10.64898/2026.03.17.712179v3
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Search Authors: Adn Pinto-Fernndez Claire Heride Andrew P Turnbull Dora Pedroso Victoria Smith Lisa Mullee Wojciech W Krajewski Cameron Bell Anthony Varca Thomas Charlton Dylan T Jones Tom E McAllister Roman Fischer Elena Navarro-Guerrero Daniel Ebner Akane Kawamura Sunkyu Kim Dave Guerin Tim R Hammonds Jeffrey Kearns Christopher Dinsmore Neil Jones Sara J Buhrlage David Komander Sylvie Urb Michael J Clague Benedikt M Kessler, 
    AGING    BRAIN    CANCER   

Mca25-003

A Brain-Aging Transcriptomic Signature Reclassifies WHO Glioma Grade and Predicts Survival Independently of IDH Status: A Multi-Cohort Study

Abstract: https://www.medrxiv.org/content/10.64898/2026.06.10.26355414v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.06.10.26355414v1.full-text
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Search Authors: Mohamed Saadawy osama khatan Eslam Saadawy, 
    CANCER   

Mca25-004

Distinct neuronal, proliferative, and secretory pathways are perturbed in cancer survivors with depressive symptoms

Quote: Conclusions Distinct biological mechanisms related to neurodegeneration, reward circuitry, autonomic secretion, and proliferative signaling may underlie depression in cancer survivors. Inflammation was implicated as a shared mechanism of depression across cancer and non-cancer populations. This study identifies potential therapeutic targets and highlights the need for precision medicine in treating depression among cancer survivors.
Abstract: https://www.medrxiv.org/content/10.64898/2026.06.16.26355016v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.06.16.26355016v1.full-text
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Search Authors: Julia Trudeau Nidhi Thati Ding Quan Ng Esther Chavez-Iglesias Adam B. Olshen Anand Dhruva Jason W. Chan Raymond J. Chan Alexandre Chan Kord M. Kober, 
    CANCER   

Mca25-007

What Urine Measures Is Not What Tissue Encodes: Compartment-Specific miRNA Coordination in Prostate Cancer

Abstract: https://www.medrxiv.org/content/10.64898/2026.06.14.26355623v2
Full Text: https://www.medrxiv.org/content/10.64898/2026.06.14.26355623v2.full-text
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Search Authors: Shweta Singh Pramit Biswas Sameer Trivedi Mahima Yadav Manjari Gupta Lalit Kumar Yashasvi Singh Ujwal Kumar Parimal Das Garima Jain, 
    PRIME    AGING    CANCER   

Mca25-008

A Poisson Process Life Expectancy framework for optimising patient lifetime during chemotherapy

Quote: Mortality is modelled as a Poisson processes, a framework that enables the patients expected lifetime to be computed. The model and objective are biologically interpretable and can in principle be calibrated using clinical data. We demonstrate the approach for a logistic tumour growth model, illustrating the trade-offs between tumour control and toxicity.
Abstract: https://www.medrxiv.org/content/10.64898/2026.06.15.26354436v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.06.15.26354436v1.full-text
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Search Authors: Byron D. E. Tzamarias Nigel J. Burroughs, 
    CANCER   

Mca25-015

T Cell Receptor repertoire analysis reveals antigenic convergence and immunotherapeutic opportunities in Prostate Cancer

Quote: Conclusions These findings reveal an oligoclonal, antigen-driven intratumoral TCR#946; landscape and identify PSGR and PSMA as immunogenic, potentially actionable targets. Integration of TCR profiling with antigen discovery pipelines may support the development of TCR-based biomarkers and precision immunotherapeutic strategies in prostate cancer.
Abstract: https://www.medrxiv.org/content/10.64898/2026.06.12.26355376v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.06.12.26355376v1.full-text
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Search Authors: Abatino Antonio Giordano Caterina Isdraele Romano Lisa Fiume Giuseppe Sarubbi Maria Chiara Malanga Donatella Amodeo Antonio Alba Stefano Alberto Piana Cristian Fiori Damiano Rocco Cantiello Francesco Crocerossa Fabio Cuda Giovanni Gallo Raffaella Aversa Ilenia Palmieri Camillo, 
    CANCER   

Mca25-017

Longitudinal multi-omics characterization of the malignant evolution in multirelapsing glioblastoma

Abstract: https://www.medrxiv.org/content/10.64898/2026.06.11.26355035v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.06.11.26355035v1.full-text
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Search Authors: Madeleine H. Lackman Christopher Wardell Emilie Darrigues Annick De Loose A. Geoffrey Lyle Yuanqing Xue Katrina Learned Allison Cheney Olena M. Vaske Sinem Karaman Vadim Le Joncour Analiz Rodriguez, 
    CANCER   

Mca25-018

Panel-level multilocus methylation quantification in native cell-free DNA by PCR-compatible sequential enzymatic processing

Quote: Plasma proof-of-concept analyses showed discriminatory signal in CRC and proof-of-concept transferability to hepatocellular carcinoma. Additional platelet-retaining experiments identified a strategy to increase recovery of analyzable circulating templates while reducing genomic DNA recognition. Delta-HLD provides a compact PCR-compatible framework for low-input methylation analysis without base conversion.
Abstract: https://www.medrxiv.org/content/10.64898/2026.06.11.26354897v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.06.11.26354897v1.full-text
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Search Authors: Cintia Celina Vaquer Paula Alida Wetten Clara Garca Samartino Jorge Daniel Rodriguez Nicols Ricardo Manzino Roberto Prez Ravier Agustina Renata Angeloni Rodrigo Damin Militello Alejandro Ledesma Juliana Sesma Yanina Agnella Erika Gudio Fracchia Daz Carina Evelyn Rodrigo Ongay Guillermo Sanguinetti Agustn Correa Melani Carlen Walter Ramn Minatti Gastn Andrs Vaschalde Paula Valdemoros Leandro Sarrip Luis Mayorga Victoria Bocanegra Emanuel Martn Campoy, 
    CANCER   

Mde25-005

DKK1 and CKAP4 expression is associated with cervical lymph node metastasis in tongue squamous cell carcinoma

Abstract: https://www.medrxiv.org/content/10.64898/2026.05.29.26354440v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.05.29.26354440v1.full-text
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Search Authors: Hironori Fujita Osamu Takahashi Naomi Yada Jumpei Tanaka Kazuya Haraguchi Masahiko Morioka Tatsuki Yaginuma Masaaki Sasaguri Shoichiro Kokabu Manabu Habu, 
    CANCER   

Mga25-007

Conversational Artificial Intelligence-Enabled Precision Oncology Reveals Context-Specific TGF and JAK/STAT Alterations in Pancreatic Cancer

Abstract: https://www.medrxiv.org/content/10.64898/2026.06.10.26355398v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.06.10.26355398v1.full-text
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Search Authors: Fernando C. Diaz Brigette Waldrup Francisco G. Carranza Sophia Manjarrez Enrique Velazquez-Villarreal, 
    CANCER    GENETICS   

Mge25-009

MOSAIC: Methylation-Oriented Site Analysis and Information Classifier for Robust Epigenomic Classification of Acute Leukemia in Clinical Cohorts with Variable Tumor Purity

Abstract: https://www.medrxiv.org/content/10.64898/2026.06.16.26355747v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.06.16.26355747v1.full-text
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Search Authors: Atharva Jaydeep Shah Donald Green Lauren Wainman Jeremiah Karrs Parth Shah, 
    CANCER   

Mpt25-010

Cytoplasmic staining of T cell receptor components enables efficient assessment of lineage and clonality in surface CD3-negative T cell neoplasms

Abstract: https://www.medrxiv.org/content/10.64898/2026.06.02.26354783v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.06.02.26354783v1.full-text
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Search Authors: Aaron J. Wilk Gary Gitana Jean Oak, 
    CANCER   

Mpt25-011

Understanding Human"AI Discrepancy in Breast Cancer TIL Assessment: A Multi-Rater and Perceptual Bias Study

Abstract: https://www.medrxiv.org/content/10.64898/2026.05.29.26354196v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.05.29.26354196v1.full-text
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Search Authors: Abdulkerim Capar Ibrahim Aloglu Fugen Aker Mucahit Ertano Yusuf Emir Mese Alptug Ungor Berfin Ekin Yldz, 
    CANCER   

Mur25-009

Two-Year Outcomes from the PRESERVE Trial: Durable Oncologic Control Following Focal Irreversible Electroporation Ablation for Intermediate-Risk Prostate Cancer

Abstract: https://www.medrxiv.org/content/10.64898/2026.05.08.26352470v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.05.08.26352470v1.full-text
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Search Authors: Jonathan A. Coleman Arvin K. George span classnlm-collab data-hwp-idcollab-1the Society of Urologic Oncology Clinical Trials Consortium (SUO-CTC), 

  Javilk's Research Links for Week 25
Updated 06/27/2026-03:36:32 AM
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