This common vitamin deficiency can mimic normal aging

Common pesticide linked to more than double the risk of Parkinsons disease

Chlorpyrifos has been used on agricultural crops for decades. Although residential uses of the pesticide were banned in 2001 and agricultural applications faced restrictions in 2021, the chemical continues to be used on a variety of crops in the United States and remains common in many other countries.

Scientists may have finally found how Alzheimers spreads through the brain

Gut-derived serine protease reduces sleep but extends lifespan

Body composition subphenotypes, cardiometabolic risk and incident outcomes: validation in the population-based NAKO and UK Biobank imaging cohorts

An empirical Bayes framework for burden and dispersion association tests helps prioritize rare variants associated with Alzheimers disease

A next-generation electronic frailty index leveraging deep learning on unstructured health records extends risk prediction across the full frailty spectrum

Evaluation of the efficacy of Ashwagandha in chronic knee pain among older adults with knee osteoarthritis " Protocol of a double-blind randomized controlled trial

Multidimensional motivation in aging: a validated framework spanning goal-directed behaviour, social reward and pleasure

Optimal vaccination in aging populations under age-dependent infection fatality risks

Sex-biased Genetic Risk Loci and Causal Brain Proteins in Parkinsons Disease

Stratified cohorts for biomarker assessment and trial readiness: TMEM175, SCARB2 and CTSB in Parkinsons disease

Human IL-34 Deficiency Primes Microglia Toward Alzheimers Disease-Associated States

Routine implementation of -synuclein Seed Amplification Assays reveals high diagnostic performance and the limited value of Alzheimer disease fluid biomarkers for detecting -synuclein co-pathology

TSPO PET binding in vivo reflects increased phagocytic microglia at post mortem in people with frontotemporal dementia

Brain inflammation is a key feature of frontotemporal dementia (FTD). TSPO PET is widely used as an in vivo proxy for neuroinflammation, but whether the elevated signal reflects microglial, astrocytic, or vascular pathology is controversial.

Aging-Related lncRNA Expression in Bipolar Disorder: Effects of Familial Liability and Childhood Trauma

Genetic overlap with schizophrenia and Parkinsons reveals psychomotor basis of physical activity

Better immediate declarative memory is associated with forgetting during locomotor adaptation in chronic stroke and in older adults