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PRIME
CANCER
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Aac26-002 | USC scientists just unlocked an endless supply of cancer-fighting immune cells |
| Quote: |
Published in the journal Cell, the study focuses on
granulocyte-monocyte progenitors (GMPs), a type of progenitor cell that
produces macrophages and several other immune cells. Macrophages play a
key role in defending the body against infections and have attracted
growing interest as potential tools for treating cancer. The
researchers showed that GMPs can be expanded extensively in the
laboratory and genetically modified to recognize cancer cells while
also boosting broader immune responses.
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| Article:
| https://www.sciencedaily.com/releases/2026/06/260620100317.htm |
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PRIME
CANCER
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Aac26-004 | Scientists discover an unexpected way to make pancreatic cancer cells self-destruct |
| Quote: |
Researchers tested experimental PCAI compounds against pancreatic
cancer cells and found they had powerful anticancer effects. One
leading compound blocked more than 90 of cancer cell migration,
suggesting it could help prevent the spread of tumors. Rather than
suppressing cancer signaling, the treatment hyperactivated key pathways
until the cells essentially self-destructed.
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| Article:
| https://www.sciencedaily.com/releases/2026/06/260622091512.htm |
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CANCER
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Bcb25-007 | The novel curcumin analogue AKT-100 targets both mutant p53 and STAT3 in gynecologic cancer cells |
| Article:
| https://www.biorxiv.org/content/10.1101/2025.10.06.680794v3 |
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| Search Authors: |
Geneva L. Williams Lane E. Smith Jamie L. Padilla Alexander S. Goss Daisy Belmares-Ortega Xiangxiang Wu Jennifer N. Daw Sumegha Mitra Prakash Jagtap Josh K. Monts Jun-yong Choe Kimberly K. Leslie,
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CANCER
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Bcb25-009 | Molecular and Functional Analysis of Calcium Binding by a Cancer-linked Calreticulin Mutant |
| Article:
| https://www.biorxiv.org/content/10.1101/2025.06.25.661618v3 |
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| Search Authors: |
Ishmael Nii Ayibontey Tagoe Amanpreet Kaur Osbourne Quaye Emmanuel Ayitey Tagoe Nicole Koropatkin Leslie S. Satin Malini Raghavan,
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CANCER
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Bcb25-010 | Adaptive plasticity of aspartate metabolism in succinate dehydrogenase-deficient cancer cells |
| Article:
| https://www.biorxiv.org/content/10.64898/2026.05.18.726122v3 |
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| Search Authors: |
David Sokolov Eric Zheng Serwah Danquah Madeleine L. Hart Lucas B. Sullivan,
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CANCER
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Bcb25-015 | tRF-3021a Supports Invasiveness, Apoptosis Resistance, and Global Protein Synthesis in Cancer Cell Lines |
| Article:
| https://www.biorxiv.org/content/10.64898/2026.01.26.701835v2 |
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Fatemeh Esmaeili Kumarjeet Bannerjee Ajay Chatrath Divya Sahu Yoshiyuki Shibata Shekhar Saha Pankaj Kumar Zhangli Su Anindya Dutta,
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CANCER
GENETICS
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Mca26-006 | Epigenetic patterns and methylation-based models for robust outcome prediction in osteosarcoma |
| Abstract:
| https://www.medrxiv.org/content/10.1101/2025.11.19.25340108v3 |
| Full Text:
| https://www.medrxiv.org/content/10.1101/2025.11.19.25340108v3.full-text |
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| Search Authors: |
Joshua J. Bowers Nikhil Ramavenkat Christopher E. Lietz Miya Hugaboom Aditya Madupur Edwin Choy Gregory M. Cote Hang Lee Martin J. Aryee Dimitrios Spentzos,
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CANCER
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Mca26-007 | INCREASED REMOVAL SIGNALS ON ERYTHROCYTES OF ANEMIC CANCER PATIENTS |
| Abstract:
| https://www.medrxiv.org/content/10.64898/2026.06.23.26356301v1 |
| Full Text:
| https://www.medrxiv.org/content/10.64898/2026.06.23.26356301v1.full-text |
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Dimitris Matthaios George Karatidis Ioanna Balgkouranidou Zoe Kyriakou Konstantinos Anagnostopoulos Charalampos Papadopoulos,
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CANCER
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Mca26-008 | Genetically Proxied Interleukin-6 Inhibition and Cancer Risk: A Multi-Ancestry Drug-Target Mendelian Randomization Study of Hepatocellular Carcinoma and Colorectal Cancer |
| Abstract:
| https://www.medrxiv.org/content/10.64898/2026.06.21.26356179v1 |
| Full Text:
| https://www.medrxiv.org/content/10.64898/2026.06.21.26356179v1.full-text |
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| Search Authors: |
Muhammad Muneeb Ahmad Ranjha Hamna Munir,
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AI-CHAT
CANCER
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Mca26-009 | Five-Year Breast Cancer Risk Prediction From Screening Breast Ultrasound Using Deep Learning |
| Abstract:
| https://www.medrxiv.org/content/10.64898/2026.06.21.26356188v1 |
| Full Text:
| https://www.medrxiv.org/content/10.64898/2026.06.21.26356188v1.full-text |
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| Search Authors: |
Yuxuan Chen Haoyan Yang Yanqi Xu Ria Soni Laura Heacock Maciej Lis Aleksandra Stanek Tomasz Puto Alana Amarosa Lewin Linda Moy Freya Schnabel Yiqiu Shen,
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CANCER
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Mca26-010 | Pembrolizumab, Temozolomide and HSPPC-96 Vaccine in Newly Diagnosed Glioblastoma Post-Chemoradiation: Results from a Multi-institutional, Phase 2, Randomized, Placebo-Controlled Trial |
| Abstract:
| https://www.medrxiv.org/content/10.64898/2026.06.22.26354817v1 |
| Full Text:
| https://www.medrxiv.org/content/10.64898/2026.06.22.26354817v1.full-text |
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| Search Authors: |
Byram H. Ozer Scott M. Lindhorst Ryan T. Merrell Christopher R. Trevino Jeremy D. Rudnick Nicolas G. Avgeropoulos Naren Ramakrishna Simon Khagi Yasmeen Rauf Tobias Walbert Edward Pan Michael Youssef Karen L. Fink Jacob J. Mandel Lynne P. Taylor Howard Colman Erin M. Dunbar Nina Paleologos Eric C. Burton Jing Wu Heather E. Leeper Javier Gonzalez Marta Penas-Prado Jeffrey J. Raizer Eleonora Veglia Sandra Craig Ying Yuan Claudia Chambers Kathleen Wall Ewa Grajkowska Tito Mendoza Terri S. Armstrong Mark R. Gilbert,
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CANCER
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Mca26-013 | Comparative Immunotherapeutic Strategies in Advanced Melanoma: A Systematic Review and Bayesian Meta-analysis of TIL and Engineered Viral Vector Therapies |
| Abstract:
| https://www.medrxiv.org/content/10.64898/2026.05.26.26353583v2 |
| Full Text:
| https://www.medrxiv.org/content/10.64898/2026.05.26.26353583v2.full-text |
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Joshua Anyachor,
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AI-CHAT
CANCER
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Mph26-003 | Generalizable AI predicts immunotherapy outcomes across cancers and treatments |
| Abstract:
| https://www.medrxiv.org/content/10.1101/2025.05.01.25326820v4 |
| Full Text:
| https://www.medrxiv.org/content/10.1101/2025.05.01.25326820v4.full-text |
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Wanxiang Shen Intae Moon Thinh H. Nguyen Michelle M. Li Yepeng Huang Nitya Nair Daniel Marbach Marinka Zitnik,
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CANCER
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Mur25-003 | Urinary Creatine Riboside Complements PSA to Improve Disease Detection in the Diagnostic Gray Zone of Prostate Cancer |
| Abstract:
| https://www.medrxiv.org/content/10.64898/2026.06.16.26355797v1 |
| Full Text:
| https://www.medrxiv.org/content/10.64898/2026.06.16.26355797v1.full-text |
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Daxesh P. Patel Ashlie Santaliz Casiano Leila Toulabi Mohammed Khan Tiffany H. Dorsey Ewy A. Math Curtis C. Harris Xin Wei Wang Stefan Ambs,
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PRIME
CANCER
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Zzc26-004 | Prostate Cancer: Overdiagnosis: The Central Problem |
| Quote: |
By the time men reach their seventies and eighties, a substantial
proportion harbour microscopic prostate cancers that will never cause
symptoms or death. PSA screening detects many of these slow-growing,
clinically insignificant cancers. Once a man is told he has cancer,
psychological pressure and medical norms create powerful incentives to
treat. But treatment prostatectomy, radiotherapy, hormone therapy
carries substantial harms, and many men end up treated for cancers that
would never have progressed.
|
| Article:
| https://principia-scientific.com/why-jeremy-clarkson-was-well-meaning-but-wrong/ |
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