PRIME BRAIN COGNITION SLEEP
Aaa26-005	Warmer night-time temperatures are linked to poorer associative memory performance
	Quote:	Higher minimum, but not maximum, temperature was associated with poorer performance on Paired Associates, a task assessing associative memory. This pattern was observed for air temperature, wet-bulb temperature, and temperature percentile, suggesting poorer memory performance after warmer nights, both in absolute terms and relative to local seasonal norms. Temperature was not significantly associated with performance on any other task, including measures of short-term/working memory, visuospatial processing, language, attention, or executive function.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.06.18.26356006v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.06.18.26356006v1.full-text
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	Search Authors:	Anna Behler Renate Thienel Nicholas Bayliss Felicity Simpson Kerrie McAloney Jessica Adsett Nicholas G. Martin Michael Breakspear Michelle K. Lupton,
PRIME BRAIN COGNITION
Mne26-007	Automated EEG Classification to Track Levels of Consciousness
	Quote:	As proof-of-principle for clinical implementation, we apply the classifier to a continuous EEG record from a patient with acute severe traumatic brain injury in the ICU, demonstrating its ability to yield continuous ABCD classifications that capture state fluctuations with high temporal and spatial resolution. The automated ABCD classifier allows for efficient analysis of continuous EEG records, facilitating the translation of the ABCD framework to the bedside for patients with acute severe brain injuries.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.06.18.26355981v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.06.18.26355981v1.full-text
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	Search Authors:	William H. Curley Andrew Hoopes David W. Zhou Mary M. Conte Jonathan D. Victor Nicholas D. Schiff Brian L. Edlow,
AGING COGNITION
Mne26-009	Human IL-34 Deficiency Primes Microglia Toward Alzheimers Disease-Associated States
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.02.21.26346696v2
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.02.21.26346696v2.full-text
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	Search Authors:	Francisco Hernandez-Rasco Roco Ruiz Itziar de Rojas Raquel Puerta Clara Garcia-Mayor Ana Mara Espinosa-Oliva Juan Garca-Revilla Paula Bayon Alberto Rivera-Ramos Farah Real Oualit Sebastin Jimnez Maria Eugenia Saez Roco M. de Pablos Feiyang Zhao Claudia Olive Pilar Sanz Xavier Montalbn Sergi Valero Amanda Cano Mara Victoria Fernndez Anne Marie Wells Jose Enrique Cavazos Sudha Seshadri Merce Boada Santos Maes Michael T. Heneka Francisco Javier Vitorica Alfredo Ramirez Jos Luis Venero Agustn Ruiz,
PRIME BRAIN COGNITION METABOLISM NUTRITION
Mne26-010	Metabolism of the antioxidant micronutrient ergothioneine as a plasma biomarker of cognitive resilience in older people with Alzheimers disease amyloid pathology
	Abstract:	https://www.medrxiv.org/content/10.1101/2025.07.31.25332054v4
	Full Text:	https://www.medrxiv.org/content/10.1101/2025.07.31.25332054v4.full-text
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	Search Authors:	Joyce R. Chong Irwin K. Cheah Richard M. Tang Barry Halliwell Christopher P. Chen Mitchell K.P. Lai,
AGING BRAIN COGNITION
Mne26-014	Routine implementation of -synuclein Seed Amplification Assays reveals high diagnostic performance and the limited value of Alzheimer disease fluid biomarkers for detecting -synuclein co-pathology
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.04.21.26351389v2
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.04.21.26351389v2.full-text
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	Search Authors:	Ocane Jourdan Marie Duchiron Joan Torrent Cdric Turpinat Etienne Mondesert Germain Busto Mehdi Morchikh Morgan Dornadic Constance Delaby Christophe Hirtz Lou Thizy Genevieve Barnier-Figue Florence Perrein Snejana Jurici Audrey Gabelle Karim Bennys Sylvain Lehmann,
COGNITION
Mot25-010	The impact of cognitive processes associated with image recognition on visuo-vestibular interaction
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.04.22.26351361v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.04.22.26351361v1.full-text
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	Search Authors:	Pasquale Malara Andrea Giorgia Tosin Andrea Castellucci Salvatore Martellucci Lucia Beln Musumano Marco Mandal,
COGNITION PAIN PSYCHOLOGY
Mpa26-003	Pain Catastrophizing, Pain Self-Efficacy, and their Interaction as Predictors of Health Outcomes in Chronic Pain
	Quote:	Conclusion Pain self-efficacy interacted with pain catastrophizing to predict physical function and loneliness at 3 months. Greater self-efficacy was associated with better outcomes, with associations diminished with higher levels of pain catastrophizing. Findings highlight the moderating role of adaptive and maladaptive cognitions and suggest interventions should address both processes to optimize recovery in physical and social functioning.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.06.15.26355697v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.06.15.26355697v1.full-text
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	Search Authors:	Emma Raney Troy C. Dildine Samsuk Kim Sean C. Mackey Dokyoung S. You,
AGING BRAIN COGNITION
Mpt26-003	TSPO PET binding in vivo reflects increased phagocytic microglia at post mortem in people with frontotemporal dementia
	Quote:	CD68 burden was elevated in FTD, concentrated in white matter, and correlated with regional TSPO PET binding across pathologies (#946; 8.40, P 0.001). Only the CD68TSPO co-localised fraction tracked the PET signal, with no TSPO upregulation per-cell. The elevated TSPO PET signal in FTD likely reflects an increased burden of lysosome-enriched CD68 microglia, supporting TSPO PET as a microglial-burden biomarker in both FTLD-tau and FTLD-TDP.... Brain inflammation is a key feature of frontotemporal dementia (FTD). TSPO PET is widely used as an in vivo proxy for neuroinflammation, but whether the elevated signal reflects microglial, astrocytic, or vascular pathology is controversial.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.06.22.26356176v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.06.22.26356176v1.full-text
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	Search Authors:	Davi S. Vontobel Kei Onn Lai Mehtap Bacioglu George Nolan Daniel C Maddison Amelie Adamski Julia Goddard Noah L. Shapiro Harry Crook Tim Fryer Young Hong Sasvi Wijesinghe Franklin Aigbirhio Edward Avezov Kieren S. J. Allinson Annelies Quaegebeur John T OBrien James B Rowe Maria Grazia Spillantini Maura Malpetti,
BRAIN COGNITION HEART PSYCHOLOGY
Mpy26-004	Brain and vascular integrity related to cognitive and motor flexibility in autism: a study protocol
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.06.24.26356429v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.06.24.26356429v1.full-text
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	Search Authors:	Erik Domellf Andreas Johansson Sara Stillesj Linnea Karlsson Wirebring Carola Wiklund-Hrnqvist Anna-Maria Johansson Thomas Rudolfsson Anders Whlin Gustaf Wadenholt Malin Ekesryd Nordstrm Daniel Sfstrm,
AGING COGNITION PSYCHOLOGY
Mpy26-005	Aging-Related lncRNA Expression in Bipolar Disorder: Effects of Familial Liability and Childhood Trauma
	Quote:	Conclusions Aging-related lncRNA alterations mark familial vulnerability to BD and are shaped by childhood trauma within a geneenvironment interaction framework.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.06.15.26355706v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.06.15.26355706v1.full-text
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	Search Authors:	Sultan Ekinci Buket Yeilolu brahim Fettaholu Canay Pamuku nl Hidayet Ece Arat elik evin Hun enol Sinem Bala Esma rekli Kaymak Burcu Kk Kendirliolu Mark A. Frye Ayegl zerdem Merih Altnta Deniz Ceylan,
BRAIN COGNITION PSYCHOLOGY
Mpy26-006	Early deviations from normative brain morphology and cortical microstructure in schizophrenia spectrum disorders
	Quote:	No interaction with SSD diagnosis was found. Furthermore, positive symptoms correlated negatively with CT and FA tract-based centiles, and showed widespread positive associations with raw cMD, whereas negative symptoms showed no associations. These findings underscore multimodal brain abnormalities that originate early in the course of SSD and their distinct associations with symptoms. Our results support the potential of both normative modelling and diffusion imaging markers to identify individualized early brain changes in SSD Among these, cMD emerges as a potential marker of SSD-related microstructural alterations.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.01.09.26343760v2
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.01.09.26343760v2.full-text
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	Search Authors:	Claudio Alemn-Morillo Natalia Garca-San-Martn Richard AI Bethlehem Patricia Segura Chloe Gomez Alessia Pasquini Pablo Salguero-Quiros Lena Dorfschmidt Manuel Muoz-Caracuel Rosa Ayesa-Arriola Javier Vzquez-Bourgon John Suckling Miguel Ruiz-Veguilla Benedicto Crespo-Facorro Rafael Romero-Garca,
BRAIN COGNITION PSYCHOLOGY REPRODUCTION
Mpy26-007	Sensitive periods for prenatal alcohol exposure shape internalizing symptoms across development
	Quote:	Prenatal alcohol exposure (PAE) is associated with lasting cognitive and neurodevelopmental deficits and can quadruple risk for depression later in life.... Conclusions and Relevance Our results highlight the second and third trimesters as potential sensitive periods for the impact of PAE on rising depressive symptoms from childhood to adolescence. Ultimately, these findings could inform the design of prevention programs, and facilitate targeted interventions to youth at elevated risk for depression.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.06.23.26356366v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.06.23.26356366v1.full-text
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	Search Authors:	Ka Ying Toby Law Madison E. Bigler Emma Kohrt Alex S. F. Kwong Alexandre A. Lussier,
AGING COGNITION PSYCHOLOGY
Mpy26-009	Genetic overlap with schizophrenia and Parkinsons reveals psychomotor basis of physical activity
	Quote:	Conclusions Despite negligible genetic correlations, physical activity shares substantial genetic architecture with schizophrenia and PD. Shared genes implicated brain regions and traits spanning motor and cognitive-affective function, consistent with the psychomotor nature of physical activity.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.06.23.26356304v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.06.23.26356304v1.full-text
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	Search Authors:	Kristien van der Walt Alexey Shadrin Markos Tesfaye Dennis van der Meer Ole A. Andreassen Jaroslav Rokicki Megan Campbell,
BRAIN BRAINWAVE COGNITION PSYCHOLOGY RIGHTS
Mpy26-010	Cognitive-emotional responses to ultrasonic neuromodulation of anterior cingulate cortex
	Quote:	the largest effects (Cohens d #8764; 0.8) observed in pregenual and subgenual ACC in subjects with chronic pain and depression, respectively. These rapid trial-by-trial responses to ACC stimulation predicted subsequent improvements in pain and depression severity at 24 hours. Collectively, these findings reveal that transcranial ultrasound can robustly evoke immediate, target-specific, clinically meaningful changes in cognitive-emotional state, demonstrating the potential of ultrasonic neuromodulation as a tool for individualized probing of circuit function and dysfunction.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.06.22.26356085v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.06.22.26356085v1.full-text
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	Search Authors:	Brandon S. Cooper Vincent Koppelmans Thomas S. Riis Daniel A. Feldman Sarah Kwon Patrick Brashear Michael Guynn Akiko Okifuji Jan Kubanek Brian J. Mickey,

Javilk's Research Links for Week 26
Updated 07/04/2026-03:43:26 AM
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Aaa26-005

Warmer night-time temperatures are linked to poorer associative memory performance

Mne26-007

Automated EEG Classification to Track Levels of Consciousness

Mne26-009

Human IL-34 Deficiency Primes Microglia Toward Alzheimers Disease-Associated States

Mne26-010

Metabolism of the antioxidant micronutrient ergothioneine as a plasma biomarker of cognitive resilience in older people with Alzheimers disease amyloid pathology

Mne26-014

Routine implementation of -synuclein Seed Amplification Assays reveals high diagnostic performance and the limited value of Alzheimer disease fluid biomarkers for detecting -synuclein co-pathology

Mot25-010

The impact of cognitive processes associated with image recognition on visuo-vestibular interaction

Mpa26-003

Pain Catastrophizing, Pain Self-Efficacy, and their Interaction as Predictors of Health Outcomes in Chronic Pain

Mpt26-003

TSPO PET binding in vivo reflects increased phagocytic microglia at post mortem in people with frontotemporal dementia

Mpy26-004

Brain and vascular integrity related to cognitive and motor flexibility in autism: a study protocol

Mpy26-005

Aging-Related lncRNA Expression in Bipolar Disorder: Effects of Familial Liability and Childhood Trauma

Mpy26-006

Early deviations from normative brain morphology and cortical microstructure in schizophrenia spectrum disorders

Mpy26-007

Sensitive periods for prenatal alcohol exposure shape internalizing symptoms across development

Mpy26-009

Genetic overlap with schizophrenia and Parkinsons reveals psychomotor basis of physical activity

Mpy26-010

Cognitive-emotional responses to ultrasonic neuromodulation of anterior cingulate cortex