| Research Topics: |
| INDEX |
| AI-chat 4 |
| PRIME 33 |
| aging 7 |
| body 1 |
| brain 9 |
| cancer 10 |
| climate 1 |
| cognition 4 |
| covid-19 4 |
| crime 5 |
| culture 2 |
| dental 2 |
| diabetes 3 |
| diagnostics 1 |
| disease 1 |
| drugs 1 |
| economy 1 |
| election 3 |
| energy 1 |
| eyes 1 |
| gender 1 |
| genetics 4 |
| gut 3 |
| heart 5 |
| immune 4 |
| kidneys 1 |
| language 1 |
| metabolism 3 |
| microbiome 1 |
| misc 1 |
| nutrition 4 |
| obesity 1 |
| pain 1 |
| physical 1 |
| politics 8 |
| pollution 6 |
| privacy 1 |
| psychology 5 |
| quantum 3 |
| reproduction 2 |
| rights 2 |
| sleep 1 |
| soc-media |
| space 2 |
| stress 2 |
| tech 1 |
| unk |
| vaccine 4 |
| virus 3 |
| war-confl |
| war-cyber 4 |
|
Scanned: 2595 Evaluated: 284 Selected: 69 |
| PRIME CANCER | ||||||||
Aef29-1001 | Ivermectin and Fenbendazole in Cancer Care Demands Our Attention | |||||||
| Quote: | These are not just anecdotes. Hulscher and other dissenting voices argue that hundreds of studies show these drugs activate more than 12 anticancer mechanisms, including destabilizing microtubules, blocking the mTOR pathway, cutting off the glucose supply to tumors, and eliminating cancer stem cells . A recent systematic review analyzing 26 studies reportedly observed clinical improvements in leukemias and lymphomas without serious adverse effects . For patients who have run out of optionswho face the soaring costs and devastating side effects of conventional therapiesthis is a lifeline. | |||||||
| Article: | https://principia-scientific.com/ivermectin-and-fenbendazole-in-cancer-care-demands-our-attention/ | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| PRIME CANCER DRUGS | ||||||||
Aef29-1002 | Why Ivermectin Blasts the 10 Deadliest Cancers | |||||||
| Quote: | After further research, a highly significant common denominator among these 10 deadly cancers has emerged: the remodeling of the tumor microenvironment. Driven by CAFs and fibrin deposition, this remodeling leads directly to massive HIF activation and profound immune evasion. | |||||||
| Article: | https://principia-scientific.com/why-ivermectin-blasts-the-10-deadliest-cancers/ | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| CANCER | ||||||||
Bcb29-002 | Distinct Effects of the Extracellular Matrix on Tumor Organization and Response to Cancer Virotherapy | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.07.20.739578v1 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Ilaria Supino Frederique E. Visscher Annemarie Boerma Anne K Wouters Manas Joshi Mirjam HM Heemskerk Darshak K Bhatt, | |||||||
| CANCER GENETICS | ||||||||
Bcb29-003 | A Pan-Cancer Multi-Omic Analysis of Copy Number Signature Clusters and Genomic Instability | |||||||
| Quote: | Feature importance analysis highlighted expression-driven predictors and pathways linked to genomic instability. These findings show that current CNS frameworks capture complementary rather than interchangeable dimensions of tumor genome instability and suggest that multi-omic profiles can extend signature-based stratification to cohorts without whole-genome sequencing. | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.07.20.739333v1 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Marco Rota Negroni Ilaria Billato Chiara Romualdi, | |||||||
| CANCER | ||||||||
Bcb29-004 | Mapping Functional Tumor Suppressor Networks in Esophageal Adenocarcinoma Using In Vivo CRISPR Screening and Perturb-sequencing | |||||||
| Quote: | . Collectively, these findings provide a unifying framework for genomic heterogeneity in EAC, uncover underappreciated tumor suppressor pathways, and establish a resource to guide mechanistic and translational studies aimed at improving treatment strategies in this aggressive cancer. | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.07.19.739473v1 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Ebtihal H Mustafa Katherine Papastratos KaMeng Wu Niko Thio Julia V Milne Natasha Mitchell Sasha Witts Maree Pechlivanis Bonnie Wong Nicola Waddell Wayne A Phillips Nick J Clemons, | |||||||
| CANCER IMMUNE | ||||||||
Bcb29-007 | Chemokine-Dependent Natural Killer Cells Prevent Pulmonary Metastasis in a Newly Established Mouse Osteosarcoma Model | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.07.19.738728v1 | |||||||
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| Search Authors: | Jifeng Yang Frederique Zindy Shaela Fields Judith Hyle Laura J. Janke Qianqian Li Beisi Xu Qiong Zhang Gang Wu Ti-Cheng Chang Monika Wierdl Lillian M. Guenther Linda M. Hendershot Martine F. Roussel Charles J. Sherr Chunliang Li, | |||||||
| CANCER GUT | ||||||||
Bcb29-011 | Antibody-drug conjugate combination therapy targeting LGR5 and MET with different payloads enhances efficacy in preclinical colorectal cancer models | |||||||
| Quote: | Treatment with ABT-700-SG3199 increased LGR5 expression, and the combination of ABT-700-SG3199 with 8E11-CPT2 enhanced CRC cell-killing efficacy, reinforcing the rationale for a dual-targeting approach. In patient-derived xenografts, combined administration of 8E11-CPT2 and ABT-700-SG3199 markedly delayed tumor relapse and prolonged survival compared with single-agent treatment. Taken together, these findings reveal a reciprocal regulation between MET and LGR5 in response to LGR5- or MET-targeting ADCs in CRC models and support a LGR5/MET dual-targeting therapeutic strategy to enhance efficacy and potentially overcome resistance and relapse. | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.07.18.739355v1 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Shraddha Subramanian Peyton C High Cara Guernsey-Biddle Maya G Cappellino Zhengdong Liang Adela M Aldana Li Li Sheng Pan Kendra S Carmon, | |||||||
| CANCER | ||||||||
Mca29-014 | Identification of collagen features predictive of recurrence following radiotherapy for localised prostate cancer: a retrospective case control analysis | |||||||
| Quote: | Interpretation Quantitative automated analysis of ECM architecture can inform probability of prostate cancer recurrence after radiotherapy; Features relating to ECM gap size and texture are of particular relevance. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.07.16.26358234v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.07.16.26358234v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Robert P Jenkins Xiao Fu Sara Waise Monisha Dewan Clare Griffin Christine Stuttle Clare Cruickshank David Dearnaley Isabel Syndikus Emma Hall Erik Sahai Anna Wilkins, | |||||||
| CANCER | ||||||||
Mep29-003 | Associations between occupations and the occurrence of sarcomas: results of the French population-based case-control study ETIOSARC | |||||||
| Quote: | Conclusions Our study highlights hitherto unreported occupational associations with sarcomas, among both men and women, as well as the importance of sex-stratified analyses. Further research should aim to confirm these results and disentangle the respective roles of occupational exposures, environmental factors, and lifestyle characteristics. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.07.20.26358458v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.07.20.26358458v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Cline GRAMOND La Guillemin Gaelle Coureau Thomas Systchenko Karima Hammas Antonia GASH Illescas Patricia Delafosse Jean-Yves Blay Franoise Ducimetire Nicolas Penel Maud Toulmonde Franois Le Loarer Gonzague de Pinieux Isabelle Baldi Alain Monnereau Aude Lacourt Simone Mathoulin-Pelissier Brice Amadeo, | |||||||
| PRIME CANCER | ||||||||
Sd292-006 | New Antibody Drug Stops Aggressive Prostate Cancer from Spreading | |||||||
| Quote: | "The new drug has been developed to prevent metastasis, and we are very pleased and proud that we have been able to identify the mechanisms that drive cancer cell growth, invasiveness, and metastatic spread," says Marne Landstrm, Professor of Pathology at the Department of Medical Biosciences, Ume University, who led the study. | |||||||
| Article: | https://www.sciencedaily.com//releases/2026/07/260718010151.htm | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| See Also: |
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Javilk's Research Links Newsletter for Week 29 Updated 07/25/2026-03:15:16 AM What interests you? What have you found? Tell me! Drop me a note to subscribe or submit something. |