PRIME AGING DIABETES METABOLISM NUTRITION
Aae30-1006	NAD A Vital Molecule for Energy, Healthy Aging, and Cellular Repair
	Quote:	Nicotinamide adenine dinucleotide (NAD ) is one of the most essential molecules in the human body... NAD is a coenzyme derived from vitamin B3 (niacin). It functions primarily as an electron carrier, allowing cells to convert nutrients from carbohydrates, fats, and proteins into adenosine triphosphate (ATP), the bodys primary energy currency. Without adequate NAD , cells cannot efficiently produce energy.... A decline in NAD levels is now considered a hallmark of aging.
	Article:	https://richardgoldberg.substack.com/p/nad-a-vital-molecule-for-energy-healthy
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DIABETES METABOLISM OBESITY
Bpt29-014	Dronedarone hydrochloride reverses obesity-related metabolic syndrome while preserving skeletal muscle mass
	Quote:	Mechanistically, dronedarone hydrochloride operates independently of central hypothalamic appetite-regulating neuropeptides and the peripheral leptin pathway. By decoupling fat reduction from sarcopenia, our findings establish dronedarone hydrochloride as a muscle-sparing therapeutic candidate for metabolic syndrome.
	Article:	https://www.biorxiv.org/content/10.64898/2026.07.20.739085v1
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	Search Authors:	Jiaxin Lei Xiaoxun Zhang xinyu cao zhixian zhu fei ye ziqian xu wenrong su xinyue zeng zuzhi xu jingdong zhao siyi jiang nan zhao Huaizheng Liu Yan Lu Chuanzheng Sun Jin Chai,
PRIME DIABETES
Sd301-006	Why Losing the Wrong Fat Can Trigger Diabetes/a
	Quote:	When healthy adipose tissue is lost, the body can no longer manage lipids or release metabolic hormones in the usual way. This breakdown can contribute to serious conditions, including diabetes and fatty liver disease. "This is really underscoring the importance of healthy fats in keeping metabolism intact and functional," said Oral. "People think of Type 2 diabetes as a disease of beta cells, but its actually a disease of fat cells, too."
	Article:	https://www.sciencedaily.com//releases/2026/07/260726015259.htm
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PRIME DIABETES
Sd302-007	Misfolded Insulin May Be Quietly Driving Diabetes/a
	Quote:	Much like paper must be folded into the correct shape to create an origami sculpture, proteins inside cells must form precise three-dimensional structures before they can function properly. As prediabetes advances toward diabetes, this delicate process can begin to break down. Misfolded and defective proteins accumulate inside cells, creating stress that can damage the pancreatic cells responsible for producing insulin.
	Article:	https://www.sciencedaily.com//releases/2026/07/260727214616.htm
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DIABETES
Sd302-009	Why Losing Weight May Not Be Enough to Prevent Type 2 Diabetes/a
	Quote:	A healthy lifestyle can prevent type 2 diabetes for many people, but new research suggests that weight loss alone may not be enough for one particularly vulnerable group. Even after losing about 8 of their body weight and keeping it off for years, people in a high-risk category known as cluster 5 continued to experience rising blood sugar, weakening insulin production, and a strong risk of developing diabetes.
	Article:	https://www.sciencedaily.com//releases/2026/07/260724061450.htm
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	See Also:	https://www.dzd-ev.de/en/article/not-everyone-benefits-diabetes-risk-persists-despite-long-term-weight-loss
AGING BRAIN DIABETES OBESITY
Sd305-011	Scientists Discover How Obesity May Fuel Alzheimers Disease/a
	Quote:	The study, led by Houston Methodist researchers, examined how changes in body fat associated with obesity may send damaging signals to the brain. These signals appear to interfere with the brains immune system and contribute to the biological damage linked to Alzheimers disease.
	Article:	https://www.sciencedaily.com//releases/2026/07/260729051531.htm
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Javilk's Research Links Newsletter for Week 30
Updated 08/01/2026-01:13:17 AM
What interests you? What have you found? Tell me!
Drop me a note to subscribe or submit something.

Aae30-1006

NAD A Vital Molecule for Energy, Healthy Aging, and Cellular Repair

Bpt29-014

Dronedarone hydrochloride reverses obesity-related metabolic syndrome while preserving skeletal muscle mass

Sd301-006

Why Losing the Wrong Fat Can Trigger Diabetes/a

Sd302-007

Misfolded Insulin May Be Quietly Driving Diabetes/a

Sd302-009

Why Losing Weight May Not Be Enough to Prevent Type 2 Diabetes/a

Sd305-011

Scientists Discover How Obesity May Fuel Alzheimers Disease/a