| Research Topics: |
| INDEX |
| AI-chat 1 |
| PRIME 37 |
| aging 12 |
| body 2 |
| brain 17 |
| brainwave 3 |
| cancer 7 |
| climate 3 |
| cognition 10 |
| covid-19 6 |
| crime 3 |
| culture 3 |
| diabetes 6 |
| diagnostics 2 |
| disease 3 |
| drugs 1 |
| energy 1 |
| exercise 3 |
| eyes 1 |
| genetics 12 |
| gut 3 |
| heart 15 |
| immune 8 |
| kidneys 5 |
| language 2 |
| metabolism 2 |
| microbiome 2 |
| nutrition 11 |
| obesity 2 |
| physical 2 |
| politics 2 |
| pollution 2 |
| population 2 |
| practice 2 |
| privacy 2 |
| psychology 14 |
| quantum 1 |
| reproduction 2 |
| rights 1 |
| sleep 2 |
| space 1 |
| tech 2 |
| unk |
| vaccine 2 |
| virus 2 |
| war-confl |
| war-cyber 1 |
|
Scanned: 3012 Evaluated: 322 Selected: 92 |
| AGING GENETICS | ||||||||
Mcr32-018 | Intergenerational and life-course links between a cardiovascular health-related methylation score and early vascular changes | |||||||
| Quote: | Conclusions An LE8-derived DNAm score was associated with lower cIMT across the life course and, to a lesser extent, across generations. These findings suggest that blood DNAm reflects cumulative cardiovascular health and vascular burden and may complement conventional cardiovascular risk assessment. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359994v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359994v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Binisha H. Mishra Emma Raitoharju Leo-Pekka Lyytikinen Nina Mononen Juhani S. Koskinen Jorma S.A. Viikari Katja Pahkala Suvi P. Rovio Juha Mykknen Markus Juonala Mika Khnen Olli T. Raitakari Terho Lehtimki Pashupati Prasad Mishra, | |||||||
| AGING REPRODUCTION | ||||||||
Mge32-002 | The Xella Clock: a female-specific epigenetic aging clock optimized for menstrual fluid and endometrial tissue | |||||||
| Quote: | Our model, the Xella Clock, outperforms other widely used epigenetic aging clocks at predicting chronological age from MF data and on endometrial tissue. The model is a useful tool for advancing the study of female reproductive aging and can be used to examine associations between endometrial age acceleration and clinical factors. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359971v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359971v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Ananya Pavuluri Billie Gould Amit Indap Nadiia Salakh Kelly Lacob Adriana Dantas Olga Sazonova Jesus Ching, | |||||||
| AGING BRAIN GENETICS | ||||||||
Mge32-013 | TMEM106B haplotypes show distinct associations with tau and TDP-43 pathologies in the aging brain | |||||||
| Quote: | These findings identify haplotype-specific associations with differential proteinopathy burden, illustrating how haplotype-resolved analyses can connect GWAS signals to candidate molecular pathways. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.11.26359568v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.11.26359568v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Alex N. Salazar Niccolo Tesi Sven J van der Lee Frank Koopmans Ka Wan Li Susan Rohde Maruelle Luimes Annemieke Rozemuller August B. Smit Marc Hulsman Henne Holstege, | |||||||
| PRIME AGING BRAIN HEART | ||||||||
Mge32-022 | Classification of ACE variants related to Alzheimers disease (AD): the ACE mutations " AD browser | |||||||
| Quote: |
Background ACE variants are genetic risk factors for Alzheimers disease
(AD), potentially through reduced enzymatic activity and impaired
amyloid-#946; hydrolysis....
Conclusions Variants associated with reduced blood ACE levels were estimated to be carried by approximately 1 in 25 individuals in the general population. This frequency is of the same order of magnitude as the 13.2 prevalence of Alzheimers dementia in individuals aged 7584 years (Alzheimers Association, 2025), consistent with the hypothesis that ACE deficiency may represent an underrecognized contributor to late-onset AD susceptibility. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.09.26360046v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.09.26360046v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Anastasiia A. Buianova Ivan A. Adzhubei Petr A. Buianov Olga V. Kryukova Olga A. Kost Mikhail Iu. Kuznetsov Steven M. Dudek Denis V. Rebrikov Sergei M. Danilov, | |||||||
| AGING KIDNEYS | ||||||||
Mkd32-014 | Efficacy and Safety of Sodium-Glucose Cotransporter 2 Inhibitors in the Very Elderly with Chronic Kidney Disease: a Retrospective Cohort Study Using Real-World Data | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.11.26360158v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.11.26360158v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Jonas Michael Willerding Anette Melk Kai Schmidt-Ott Robert Greite Wilfried Gwinner Julian Doricic Bernhard Magnus Wilhelm Schmidt, | |||||||
| AGING COGNITION LANGUAGE PSYCHOLOGY | ||||||||
Mne32-005 | Multimodal Speech Composites Separate Age-Related, Subjective, and Clinical Cognitive Change in Narrative Recall Tasks | |||||||
| Quote: | Theory-driven multimodal composites reveal qualitatively distinct cognitive signatures across the aging-to-impairment continuum from a single brief task, with embedding-based features capturing variation invisible to standard scoring. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359965v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359965v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Michael J Kleiman Mirza Baig Natasha Clarke Andres Salcedo James E Galvin, | |||||||
| AGING COGNITION | ||||||||
Mne32-007 | A Biologically Constrained Continuous-Time Framework for Long-Horizon Cognition Forecasting in Alzheimers Disease | |||||||
| Quote: |
The model also supports prognostic enrichment for Alzheimers clinical
trials, achieving up to 2.70x enrichment over the cohort base rate.
These results demonstrate that embedding biological disease mechanisms
within continuous-time deep learning improves the accuracy, biological
plausibility, and clinical utility of long-horizon cognitive
forecasting. The code is publicly available at: https:
github.com/PonDeepika/BEACON. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359964v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359964v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Pon Deepika Suresh Sunkari Sai Koundinya Upadhyayula span classnlm-collab data-hwp-idcollab-1The Alzheimers Disease Neuroimaging Initiative Vaanathi Sundaresan, | |||||||
| PRIME AGING COGNITION | ||||||||
Mne32-011 | Plasma p-tau217 and NfL predict incident dementia in the community | |||||||
| Quote: | The association of p-tau217 with incident dementia differed by sex. DISCUSSION: These findings support the use of blood-based biomarkers for population-level dementia risk stratification, underscore the value of combining markers to improve prognostic precision, and can aid clinicians using plasma p-tau217 or NfL in interpreting dementia risk. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359934v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359934v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Anita Lenora Sunde Diego A Tovar-Rios Audun Osland Vik-Mo Henrik Zetterberg Burak Arslan Kubra Tan Hanna Huber Karin Persson Guglielmo Di Molfetta Ilaria Pola Marit Naess Haavard K Skjellegrind Geir Selbaek Nicholas J Ashton Dag Aarsland, | |||||||
| PRIME AGING BRAIN EXERCISE | ||||||||
Sd322-005 | Exercise May Help the Aging Brain Take Out the Trash | |||||||
| Quote: |
Regular exercise may help the brain clear away harmful waste that can
build up with age. Researchers found that physical activity supports
several processes linked to the brains glymphatic cleanup system,
including better sleep, lower inflammation, and healthier blood
vessels. Because this waste-removal system becomes increasingly
important as we get older, exercise could play a meaningful role in
protecting against cognitive decline....
These benefits include reducing blood pressure and vascular stiffness, improving the activation of neurons in the brain, reducing inflammation in the brain, lowering resting norepinephrine, and improving sleep. Exercise may also increase the quality of deep sleep and enhance slow wave activity associated with brain waste clearance. | |||||||
| Article: | https://www.sciencedaily.com//releases/2026/08/260810015719.htm | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| PRIME AGING BRAIN | ||||||||
Sd324-003 | Scientists Discover the Brain Has a Fast Lane and Slow Lane for Clearing Waste | |||||||
| Quote: | During deep sleep, a water-like fluid moves around the brain and helps remove metabolic waste associated with diseases such as Alzheimers. This cleanup process is part of the glymphatic system, which was first described in 2012 by Maiken Nedergaard -- a pioneering neuroscientist and co-director of the University of RochesterCenter for Translational Neuromedicine. | |||||||
| Article: | https://www.sciencedaily.com//releases/2026/08/260811011130.htm | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| PRIME AGING BRAIN BRAINWAVE | ||||||||
Sd324-006 | Scientists Discover a Hidden Brain Rhythm That Could Improve Parkinsons Treatment | |||||||
| Quote: | Deep brain stimulation (DBS) can reduce movement problems caused by Parkinsons disease, and new research is providing a clearer picture of why the treatment works. Scientists have found that its benefits appear to depend on stimulating a specific brain network that communicates primarily through a relatively fast beta rhythm (20 to 35 Hz). | |||||||
| Article: | https://www.sciencedaily.com//releases/2026/08/260811011148.htm | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
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Javilk's Research Links Newsletter for Week 32 Updated 08/15/2026-01:24:35 AM What interests you? What have you found? Tell me! Drop me a note to subscribe or submit something. |