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Scanned: 3012
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    PRIME    BODY    GENETICS    METABOLISM    NUTRITION    OBESITY   

Aef32-1025

FNIP1 variants are associated with favourable metabolism in 1 million humans

Quote: FNIP1 knockdown in primary human hepatocytes induces lipid breakdown and lysosomal gene expression, while combined hepatic knockdown of Fnip1 with its paralogue Fnip2 or knockdown of its interactor Flcn protect against weight gain, reduce liver fat and enhance insulin sensitivity in mice fed a high-fat diet. Our study implicates the FNIP1 pathway in human energy metabolism and highlights its inhibition as a potential therapeutic strategy in cardiometabolic disease.
Article: https://pubmed.ncbi.nlm.nih.gov/42557317/
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    BRAIN    COVID-19    IMMUNE    METABOLISM    PSYCHOLOGY   

Mpy32-011

Peripheral metabolic signatures in patients with neuropsychiatric long COVID syndrome

Quote: Our results demonstrate a metabolic phenotype of long COVID patients that may reflect a dysregulation of lipid metabolism and deficits in mitochondrial energy production as potential contributors to symptom burden and brain structural alterations. These data may serve as a resource and basis for further studies aimed at investigating peripheral molecular alterations in patients with neuropsychiatric long COVID syndrome.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.07.26359942v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.07.26359942v1.full-text
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Search Authors: Dario Lucas Bergmann Sophie Neugebauer Tonia Rocktaeschl Eva-Maria Dommaschk Meng Li Alexander Weuthen Alexander Refisch Nikolai Blekic Michael Kiehntopf Andre Scherag Helgi B. Schioeth Chai K. Lim Nils Opel Martin Walter Bianca Besteher, 

  Javilk's Research Links Newsletter for Week 32
Updated 08/15/2026-01:24:35 AM
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