Research
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unk
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Scanned: 3012
Evaluated: 322
Selected: 92

 
    PRIME    BODY    GENETICS    METABOLISM    NUTRITION    OBESITY   

Aef32-1025

FNIP1 variants are associated with favourable metabolism in 1 million humans

Quote: FNIP1 knockdown in primary human hepatocytes induces lipid breakdown and lysosomal gene expression, while combined hepatic knockdown of Fnip1 with its paralogue Fnip2 or knockdown of its interactor Flcn protect against weight gain, reduce liver fat and enhance insulin sensitivity in mice fed a high-fat diet. Our study implicates the FNIP1 pathway in human energy metabolism and highlights its inhibition as a potential therapeutic strategy in cardiometabolic disease.
Article: https://pubmed.ncbi.nlm.nih.gov/42557317/
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    PRIME    GUT    MICROBIOME    OBESITY   

Mga32-013

Prophage Integration in relation to Body Mass Index-Related Gut Microbiome and Microbial Metabolism

Quote: we found that prophage carriage was associated with BMI-related microbial variations. In addition, prophage carriage was linked to altered patterns of association between bacterial host species and gut metabolic profiles. These findings suggest that prophages may contribute to variation in the bacterial hosts effect on BMI but the direction appears to be limited and species-dependent.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.11.26360202v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.11.26360202v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Zhuobing Peng Jonathan Thorsen Rebecca Vinding Frej Andreas Larsen Urvish Trivedi Sren Srensen Jakob Stokholm Dennis Sandris Nielsen Shiraz A. Shah Morten Arendt Rasmussen, 

  Javilk's Research Links Newsletter for Week 32
Updated 08/15/2026-01:24:35 AM
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