Research
Topics:
INDEX
AI-chat 1
PRIME 37
aging 12
body 2
brain 17
brainwave 3
cancer 7
climate 3
cognition 10
covid-19 6
crime 3
culture 3
diabetes 6
diagnostics 2
disease 3
drugs 1
energy 1
exercise 3
eyes 1
genetics 12
gut 3
heart 15
immune 8
kidneys 5
language 2
metabolism 2
microbiome 2
nutrition 11
obesity 2
physical 2
politics 2
pollution 2
population 2
practice 2
privacy 2
psychology 14
quantum 1
reproduction 2
rights 1
sleep 2
space 1
tech 2
unk
vaccine 2
virus 2
war-confl
war-cyber 1
 
Scanned: 3012
Evaluated: 322
Selected: 92

 
    BRAIN    HEART    PSYCHOLOGY   

Mge32-014

Metabolomic and Lipidomic Signatures of Depressive Symptoms in the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study

Abstract: https://www.medrxiv.org/content/10.64898/2026.08.10.26360141v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.10.26360141v1.full-text
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Search Authors: Chaitali Dagli Nicole D Armstrong Pranali G Patel Eric Adjei Boakye Zsuzsanna Ament Amelia Demopoulos Hermant Tiwari Virginia J. Howard W Taylor Kimberly Marguerite Ryan Irvin, 
    AGING    COGNITION    LANGUAGE    PSYCHOLOGY   

Mne32-005

Multimodal Speech Composites Separate Age-Related, Subjective, and Clinical Cognitive Change in Narrative Recall Tasks

Quote: Theory-driven multimodal composites reveal qualitatively distinct cognitive signatures across the aging-to-impairment continuum from a single brief task, with embedding-based features capturing variation invisible to standard scoring.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.07.26359965v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.07.26359965v1.full-text
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Search Authors: Michael J Kleiman Mirza Baig Natasha Clarke Andres Salcedo James E Galvin, 
    PRIME    BRAIN    BRAINWAVE    PSYCHOLOGY   

Mpy32-002

Transcutaneous auricular vagus nerve stimulation regulates subjective fear in naturalistic contexts via modulation of prefrontal neural dynamics

Quote: ehaviorally, taVNS significantly attenuated fear responses during four threat phases by content analysis: T1 (ghost appearance), T2 (escape sequence), T3 (sudden threat emergence) and T4 (suicide scene). Neurally, taVNS suppressed medial prefrontal cortex (mPFC) activation during escape (T2) and disrupted the typical fear coupling between fear experience and brain activity. Furthermore, taVNS enhanced intra-mPFC functional connectivity, suggesting a potential neural basis for modulating subjective threat appraisal. Additionally, state anxiety significantly moderated brain-behavior relationships.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.07.26359962v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.07.26359962v1.full-text
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Search Authors: Can Liu Kun Fu Qi Liu Xiaodong Zhang Siyu Zhu Xinqi Zhou Rong Zhang Benjamin Becker Keith M Kendrick Weihua Zhao, 
    GENETICS    PSYCHOLOGY   

Mpy32-007

PTSD is Associated with Advanced Epigenetic Age in 45,091 US Military Veterans

Quote: PTSD was associated with advanced epigenetic aging in the largest study to date to evaluate this question. Effects were generally small in magnitude, though meaningful when considering the personal and healthcare system impact of advanced aging in the large population of VA users with PTSD.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.07.26359954v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.07.26359954v1.full-text
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Search Authors: Erika J Wolf Rui Zhang Xiang Zhao Mark Logue Brian Despard Phillip Ma Meghan Wilkinson Kelsey Serier Adam X Maihofer Kelly Harrington J. Michael Gaziano Alexandre Pereira Mark W Miller span classnlm-collab data-hwp-idcollab-1VA Million Veteran Program, 
    COGNITION    PSYCHOLOGY   

Mpy32-009

Genetic architecture of treatment-resistant schizophrenia across East Asian and European cohorts: insights from GWAS, TWAS, and synaptic pathway analyses

Quote: Although such treatment-resistant schizophrenia (TRS) shares a substantial genetic liability with treatment-responsive schizophrenia, the limited efficacy of dopamine antagonists in TRS indicates that mechanisms beyond dopamine signalling likely contribute to treatment-resistance, requiring the identification of alternative biological pathways....

Our work suggests there is promise in pathway-level and multi-omics approaches to elucidate biologically meaningful heterogeneity within SSD and provides support for synaptic mechanisms as potential targets for understanding and stratifying treatment-resistance.

Abstract: https://www.medrxiv.org/content/10.64898/2026.08.06.26359853v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.06.26359853v1.full-text
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Search Authors: Perry BM Leung Kenneth CY Wong Sophie Smart Nick R Zhang Zoe ZY Zheng Jinghong Qiu Edoardo Spinazola Antonio Pardias Justin D. Tubbs Amy CY Liu Karen KY Ho Koi-Man Cheng Karen SY Hung Eric FC Cheung Vicki HM Ling Tomy CK Hui Ole A Andreassen Thomas R.E. Barnes Philippe Conus Benedicto Crespo Facorro Gillian A Doody Kim Q. Do Chin B Eap Eileen Joyce Ingrid Melle Paulo Menez Craig Morgan Francis A ONeill Baptiste Pignon Filip paniel Ilaria Tarricone Andrea Tortelli Alp ok Homero Vallada Javier Vzquez-Bourgon span classnlm-collab data-hwp-idcollab-1The STRATA Consortium Luis Alameda Evangelos Vassos James T.R. Walters James MacCabe Marta Di Forti Robin M Murray Hon-Cheong So Pak C Sham Simon SY Lui, 
    PRIME    IMMUNE    NUTRITION    PSYCHOLOGY   

Mpy32-010

Inflammatory dietary patterns and mental health traits in middle/old-aged adults: A bi-directional Mendelian Randomization study

Quote: Observational studies have provided evidence for positive associations between inflammatory dietary patterns (IDP) and mental health, which might be mediated by immune activation....

Conclusion Our findings identified genetic loci and functional properties of IDP and provided evidence for causal pathways with depressed affect, mood swings, irritability, and fed-up feelings. Implementing dietary advice and interventions should become part of a public mental health approach.

Abstract: https://www.medrxiv.org/content/10.64898/2026.08.07.26356140v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.07.26356140v1.full-text
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Search Authors: Huiqing Shi Jorien L Treur Yuanke Qin Janita Bralten Mirjam Bloemendaal Rob ter Horst Mihai G Netea Alejandro Arias Vasquez Jan K Buitelaar, 
    BRAIN    COVID-19    IMMUNE    METABOLISM    PSYCHOLOGY   

Mpy32-011

Peripheral metabolic signatures in patients with neuropsychiatric long COVID syndrome

Quote: Our results demonstrate a metabolic phenotype of long COVID patients that may reflect a dysregulation of lipid metabolism and deficits in mitochondrial energy production as potential contributors to symptom burden and brain structural alterations. These data may serve as a resource and basis for further studies aimed at investigating peripheral molecular alterations in patients with neuropsychiatric long COVID syndrome.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.07.26359942v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.07.26359942v1.full-text
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Search Authors: Dario Lucas Bergmann Sophie Neugebauer Tonia Rocktaeschl Eva-Maria Dommaschk Meng Li Alexander Weuthen Alexander Refisch Nikolai Blekic Michael Kiehntopf Andre Scherag Helgi B. Schioeth Chai K. Lim Nils Opel Martin Walter Bianca Besteher, 
    PRIME    BRAIN    COGNITION    PSYCHOLOGY   

Mpy32-013

Oxytocin reshapes fear control: intensity-dependent prefrontal dominance and whole-brain integration during naturalistic viewing

Quote: At the large-scale network level, OT increased communication between frontoparietal/default-mode control networks and subcortical/limbic networks during high fear indicating more integrative fear regulation. A whole-brain fear neuromarker (CAFE) further confirmed intensity-dependent OT effects. Together, these findings indicate that OT modulates post-exposure fear experience and fear-related neural dynamics in ecologically valid contexts.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.11.26360155v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.11.26360155v1.full-text
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Search Authors: Kun Fu Shuyue Xu Dan Liu Zheng Zhang Qi Liu Jingxian He Ting Xu Can Liu Junjie Wang Yuan Zhang Feng Zhou Xiaodong Zhang Chunmei Lan Mengfan Han Menghan Li Zhen Liang Bharat Biswal Keith M Kendrick Weihua Zhao Dezhong Yao Benjamin Becker, 
Search Words:
OT Oxytocin Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    PSYCHOLOGY   

Mpy32-014

AVATAR therapy for distressing auditory hallucinations: mediators of change in AVATAR1, a single blind randomised control trial with supportive counselling as active control

Quote: AVATAR therapy is an effective relational therapy for persistent distressing auditory verbal hallucinations (voices). A digital representation of the embodied persecutory voice (avatar) is created and used in a series of dialogues in which the voice hearer is supported to be more assertive and the avatar concedes power.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.11.26360172v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.11.26360172v1.full-text
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Search Authors: Miriam Fornells-Ambrojo Anca Chris Ster Philippa Garety Thomas KJ Craig Mark Huckvale Richard Emsley Clementine Edwards Amy Hardy Thomas Ward Mar Rus Calafell, 
    COGNITION    LANGUAGE    PSYCHOLOGY   

Mpy32-015

A double index for assessing symptoms in psychosis based on acoustic and semantic information

Quote: Recent computational approaches to speech in psychosis generate large multidimensional feature spaces capturing semantic and acoustic aspects of language production.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.11.26360092v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.11.26360092v1.full-text
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Search Authors: Maryia Kirdun Rui He Cemal Demirlek Jose Tomas Garcia-Molina Roya Huppi Werner Surbeck Noemi Dannecker Burcu Verim Berna Yalincetin Victor Ortiz Garcia de la Foz Rosa Ayesa Arriola Emre Bora Alicia I. Figueroa-Barra Filip Spaniel Lena Palaniyappan Iris E. Sommer Philipp Homan Wolfram Hinzen Claudio Palominos, 
    COGNITION    PSYCHOLOGY   

Mpy32-016

miR-151a-5p in Neuron-Derived Extracellular Vesicles Mediates Antidepressant Response

Quote: Moreover, administration of miR-151a-5ploaded NEVs in a model of depressive-like behavior produced rapid antidepressant-like effects. Together, these findings identify a vesicle-based mechanism linking peripheral biomarkers to central pathophysiology and demonstrate that miR-151a-5p functions both as a predictor and effector of antidepressant response.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.11.26360193v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.11.26360193v1.full-text
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Search Authors: Dariusz Zurawek Alice Morgunova Laura M Fiori Jennie Yang Reine Khoury Claudia Belliveau Maria-Antonietta Davoli Pascal Ibrahim Anjali Chawla Sierra Codeluppi Faranak Farzan Sidney H Kennedy Raymond W Lam Roumen Milev Daniel Mueller Claudio Soares Susan Rotzinger Valeria Taylor Rudolf Uher Jane Foster Benicio N Frey Naguib Mechawar Cecilia Flores Corina Nagy Gustavo Turecki, 
    GENETICS    PSYCHOLOGY   

Mpy32-019

Perinatal risk factors, DNA methylation and the development of ADHD symptoms: a high-dimensional mediation analysis

Quote: Conclusions In this first epigenome-wide mediation study of ADHD, we demonstrate a role of DNAm at birth in mediating the association of maternal smoking, birth weight and ADHD-related genetic variants with ADHD symptoms. However, lack of individual site-specific findings and the observational design limit causal biological interpretations. We therefore encourage further research of epigenetic pathways for these three risk factors.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.10.26360078v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.10.26360078v1.full-text
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Search Authors: Alexander Neumann Matthew Suderman Janine Felix Charlotte A.M. Cecil, 
    PSYCHOLOGY   

Mpy32-021

Quantifying Academic Risk Factors for Student Depression Using WHO Frameworks: Odds Ratios, SHAP Explainability, and Tipping Point Analysis

Quote: The RF model yields a tipping point at academic pressure 4.02, and interaction plots reveal how depression risk is amplified by low sleep, high financial stress, and extended study hours. These findings provide data-driven thresholds aligned with WHO-endorsed modifiable determinants to support early detection and institutional counselling.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.09.26360019v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.09.26360019v1.full-text
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Search Authors: Tanvir Ahmed Md. Rashid Al Asif, 
    PSYCHOLOGY   

Sd324-002

Why Your Brain Keeps Making the Same Decisions " Even When Better Options Exist

Quote: "Our study shows that many irrational preferences do not necessarily arise primarily from people storing values relative to other values, but rather from the fact that people tend to repeat actions they once preferred in a particular context. This pure repetition can later lead to a particular option still being preferred in new contexts or environments, even if there are equivalent or even better alternatives," explains lead author Dr. Ben Wagner.
Article: https://www.sciencedaily.com//releases/2026/08/260812015218.htm
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  Javilk's Research Links Newsletter for Week 32
Updated 08/15/2026-01:24:35 AM
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