| Research Topics: |
| INDEX |
| AI-chat 3 |
| MCS 2 |
| PRIME 26 |
| aging 9 |
| brain 5 |
| cancer 11 |
| catastrophy 1 |
| censorship 1 |
| climate 1 |
| cognition 6 |
| covid-19 1 |
| culture 2 |
| dental 1 |
| diabetes 3 |
| diagnostics 1 |
| economy 3 |
| energy 3 |
| exercise 1 |
| eyes 4 |
| genetics 7 |
| gut 1 |
| heart 2 |
| immune 5 |
| language 3 |
| law 1 |
| lungs 1 |
| metabolism 2 |
| microbiome 2 |
| misc 1 |
| nutrition 4 |
| pain 1 |
| physical 1 |
| politics 3 |
| pollution 1 |
| privacy 1 |
| psychology 3 |
| rights 1 |
| space 1 |
| vaccine 1 |
| virus 1 |
|
Scanned: 2073 Evaluated: 266 Selected: 60 |
| CANCER | ||||||||
Bcb36-002 | FANCM restrains structural genome evolution and defines a synthetic lethal dependency in BRCA1-deficient breast cancer | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.09.06.749689v1 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Arvind Panday Farah Ramadan Sameer Bikram Shah Ujwal Subedi Zachary D Stephens Annapoorna Venkatachalam Neelima Yadav Vickky Pandit Sadhana Dubey Sarah Latka Hugo Villanueva Scott H. Kaufmann, | |||||||
| PRIME CANCER | ||||||||
Bcb36-006 | Melittin-induced membrane disruption in hepatocellular carcinoma involves mtROS/GSDME-mediated pyroptosis | |||||||
| Quote: | Collectively, our findings provide, to our knowledge, the first evidence that melittin induces pyroptotic cell death in HCC cells through a mechanism involving mitochondrial oxidative stress and GSDME processing. These results extend the conventional view of melittin as a direct membrane-lytic peptide and uncover an mtROS/GSDME-associated pyroptotic mechanism underlying its antitumour activity in HCC. | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.09.05.749568v1 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | He Zang Meng Lu Nian Fan Yunzhen Yang Jianfeng Qiu Dafu Chen Rui Guo, | |||||||
| CANCER | ||||||||
Bcb36-008 | The small molecule inhibitor SU056-mediated targeting of YB1 inhibits the Rb pathway in triple-negative breast cancer tumors | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.09.05.749600v1 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Wei Wang Yeaji Kim Xiaotong Zhao Kristen Weber Bonk Ruth Keri Bin Su Khalid Sossey-Alaoui, | |||||||
| PRIME AGING CANCER | ||||||||
Bcb36-010 | Stochastic Boolean Model of Death Signaling in MCF7:5C Predicts Cell Death Inducers and Inhibitors | |||||||
| Quote: | We identified 30 resistant cell strains with double mutations and 506 drug-target combinations capable of inducing four distinct modes of cell death: direct CASP7 activation, extrinsic apoptosis, intrinsic apoptosis, and combined intrinsic/extrinsic apoptosis. Overall, our model successfully explains the drug response behavior of MCF7:5C cells, predicts mechanisms of drug resistance, and suggests treatment strategies to overcome this resistance. | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.09.05.749284v1 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Kittisak Taoma Teeraphan Laomettachit Surojeet Sengupta Yue Wang Robert Clarke Pavel Kraikivski, | |||||||
| CANCER | ||||||||
Bcb36-011 | Impact of Trastuzumab and Pertuzumab on HER2 Localization and the Estrogen Receptor Cistrome in ER /HER2 Breast Cancer | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.09.07.749891v1 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Stanley Tam Shaymaa Bahnassy Lu Jin Matthew D. McCoy Suman Ranjit Raneen Rahhal Alec T. McIntosh Douglas K. Kung Gong Tang Sandra M. Swain Rebecca B. Riggins, | |||||||
| CANCER DENTAL IMMUNE | ||||||||
Mca36-002 | A mitoxyperilysis-derived spatial signature predicts immune exclusion and survival in oral squamous cell carcinoma | |||||||
| Quote: | Our findings define a structural immune evasion axis in OSCC, offering a practical tool to guide combination therapies aimed at remodeling the myeloid-stromal barrier. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.09.04.26362241v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.09.04.26362241v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Jianlin Liu Dongyan Zhang Zhen Meng Bo Zou, | |||||||
| CANCER | ||||||||
Mca36-003 | The 14-protein lung cancer signature: questions of prediction, specificity, and causality | |||||||
| Comment: | SMoking rases 7of the proteins and the rest are not significantly related to cancer according to the article. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.09.08.26362484v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.09.08.26362484v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Amit Sud Richard Houlston, | |||||||
| CANCER CULTURE | ||||||||
Mca36-008 | Oncogene Driver Status Modulates TP53 Prognostic Impact in Advanced NSCLC | |||||||
| Quote: | Conclusions Association of TP53 PV with OS in advanced NSCLC appears to depend on co-occurrence of other driver mutations. This driver-dependent effect modification informs interpretation of TP53 status and may be useful for risk stratification in clinical practice. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.09.04.26362258v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.09.04.26362258v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Minggui Pan Chen Jiang Janet Song Shreyas Kudrimoti Jacqueline V. Aredo Heather A. Wakelee Joel W. Neal Jenny Zhao Yasmine Kamgarhaghighi Ninah S. Achacoso Aleyda V. Solorzano Pamela Tse Elaine Chung Lori Sakoda Marie Jennifer Suga Sachdev Thomas Laurel Habel, | |||||||
| CANCER LUNGS | ||||||||
Mca36-009 | A cyclooxygenase-2 associated pro-tumorigenic inflammatory signature predicts outcome after surgery in lung cancer | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.09.04.26362237v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.09.04.26362237v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Victoria Fife Christian P. Bromley Matthew Roberts Ian C. H. Lee Daisy Grainger Anshuman Chaturvedi Cong Zhou Christopher M. Fife Karen Morris Ariadna Fuertes Gassio Sophie Atkinson Shamilene Sivagnanam Konjit Betre Antonn J. Cheeseman Matthew Crowther Jonathan C. M. Wan Takahiro Karasaki David Millrine Elaine Kilgour Nicholas McGranahan Mariam Jamal-Hanjani Charles Swanton span classnlm-collab data-hwp-idcollab-1TRACERx consortium Lisa M. Coussens Philip A. J. Crosbie Caroline Dive Santiago Zelenay, | |||||||
| CANCER | ||||||||
Mur36-002 | PSMA PET SUVmax Adds Information Beyond Conventional Risk Indices in Localized Prostate Cancer: A Prospective Lesion-Level Radiopathologic Study | |||||||
| Quote: | Conclusions In this prospective lesion-level cohort, intraprostatic PSMA SUVmax was associated with increased Gleason pattern 4 and cribriform/intraductal burden but not with other common risk indices. SUVmax therefore appears to carry information additive to conventional risk factors. Further investigations examining the tumor biology that reflects SUVmax are warranted. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.09.04.26362267v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.09.04.26362267v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Georges (Camille) Motchoffo Simo Pranav Movva Jiyoun Seo Bohang Shou Daniel Vega Theodore Hagens Evan C. Norris Daniel J. Luthringer Alessandro DAgnolo Kyung Hyun Sung Jeremie Calais Wayne G. Brisbane Robert E. Reiter Timothy J. Daskivich Debiao Li Rola Saouaf Hyung L. Kim Adam B. Weiner, | |||||||
| PRIME CANCER | ||||||||
Sd363-037 | Scientists Find a New Weakness in Treatment-Resistant Prostate Cancer | |||||||
| Quote: | Earlier research had linked the loss of two genes, TP53 and RB1, with transdifferentiation in prostate cancer. Exactly why losing those genes causes such a dramatic change in tumor cell identity, however, remained unclear. To investigate, the researchers examined several prostate cancer cell lines and studied which cellular pathways changed when TP53 and RB1 were missing. "We saw that there are two sides to this transition: loss of glandular genes and activation of cell programs that cause the identity to switch into stem cells," said Joshi Alumkal, M.D., Professor of Internal Medicine-Hematology/Oncology and member of Rogel Cancer Center. | |||||||
| Article: | https://www.sciencedaily.com//releases/2026/09/260904000324.htm | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
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Javilk's Research Links Newsletter for Week 36 Updated 09/15/2026-02:09:31 AM What interests you? What have you found? Tell me! Drop me a note at Javilk.com to subscribe or submit something. |