Research
Topics:
INDEX
AI-chat 3
MCS 2
PRIME 26
aging 9
brain 5
cancer 11
catastrophy 1
censorship 1
climate 1
cognition 6
covid-19 1
culture 2
dental 1
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diagnostics 1
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eyes 4
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microbiome 2
misc 1
nutrition 4
pain 1
physical 1
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psychology 3
rights 1
space 1
vaccine 1
virus 1
 
Scanned: 2073
Evaluated: 266
Selected: 60

 
    GENETICS   

Bbc36-005

Structure of the human mitochondrial RNA degradosome reveals a distinct mode of helicase-nuclease coupling

Article: https://www.biorxiv.org/content/10.64898/2026.09.06.749684v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Paula Favoretti Vital do Prado Saruby Sharma Arjun Bhatta Ana Vuckovic Maral Parvizian Marani Andrei Philipp Llarena David Bernhard Kuhle Hauke S. Hillen, 
    COVID-19    GENETICS   

Bbc36-006

Cathepsin K Mediates the Formation of Potential Rheumatoid Arthritis-Relevant Cis- and Trans-Spliced Peptides Compatible With HLA-DR4 Presentation

Quote: Rheumatoid arthritis (RA) is characterized by a loss of immunological tolerance to synovial self-proteins, yet the initial triggers generating novel neo-antigens remain incompletely defined. Here, we demonstrate that human cathepsin K (hCatK), a key cysteine protease driving joint degradation in RA, catalyzes covalent cis- and trans- splicing of peptides from major RA-associated self-proteins and foreign antigens, including type II collagen, fibrinogen, and SARS-CoV-2 Spike protein.
Article: https://www.biorxiv.org/content/10.64898/2026.09.06.749279v1
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Search Authors: Olivier Hinse S. Yasin Tabatabaei Dakhili Lee Freiburger Eliot Mar Jason Rogalski Sriram Subramaniam Eddie A. James Leonard J. Foster Dieter Brmme, 
    GENETICS   

Bbe36-006

AutoScreen: AI Co-Scientist System for Target Discovery in Functional Genomics

Quote: arget discovery in functional genomics remains largely manual and time-consuming, lacking systematic tools for efficient and reproducible gene-level hypothesis generation. We introduce AutoScreen, an AI co-scientist system supporting target discovery through both Pre-screen Design, which constructs perturbation libraries de novo from free-text research descriptions, and Post-screen Analysis, which re-ranks experimental screen hits by integrating statistical scores with biological context.
Article: https://www.biorxiv.org/content/10.64898/2026.09.06.749678v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Yuanhao Qu Xufeng Liu Xiaotong Wang Meitong Chen Xiao Luo Luna Lyu Ming Yin Jingwen Hui Di Yin Ravi Dinesh Lin Qiu Kexin Huang Hanchen Wang Shangyuan Tong Henry Cousins Ricky Feng Oswaldo Martinez Junze Zhang Tanming Chen Russ Altman Jure Leskovec Aviv Regev Mengdi Wang Le Cong, 
    GENETICS   

Mge36-003

Genetic architecture of lipoma susceptibility implicates telomere biology

Abstract: https://www.medrxiv.org/content/10.64898/2026.09.08.26362503v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.09.08.26362503v1.full-text
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Search Authors: David Bryant Lowry, 
    GENETICS   

Mge36-005

Genetic mechanisms of mitotic error in 840,853 blood genomes

Quote: These results show how genetic risk of chromosomal gains and losses varies greatly across chromosomes and across people, providing instruments for assessing the effects of mosaic aneuploidies on health.
Abstract: https://www.medrxiv.org/content/10.64898/2026.09.08.26362505v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.09.08.26362505v1.full-text
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Search Authors: Yichen Si Nolan Kamitaki David Tang Po-Ru Loh, 
    AGING    GENETICS   

Mge36-006

Rare extreme polygenic risk scores strongly indicate Alzheimers disease risk

Abstract: https://www.medrxiv.org/content/10.64898/2026.09.08.26362504v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.09.08.26362504v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Elizabeth L. Ward Peter T. Nelson Yuriko Katsumata David W. Fardo Gregory A. Jicha span classnlm-collab data-hwp-idcollab-1Alzheimers Disease Neuroimaging Initiative Justin B Miller, 
    AGING    GENETICS   

Mge36-007

Shared genetic architecture between brain iron deposition and Alzheimers disease

Abstract: https://www.medrxiv.org/content/10.64898/2026.09.07.26362470v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.09.07.26362470v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Md Rezanur Rahman Ying Xia Parnesh Raniga Amir Fazlollahi Tania Islam Aishwarya Dhruva Jue-Sheng Ong Stuart MacGregor Ashley I. Bush Jurgen Fripp Michelle K Lupton, 

  Javilk's Research Links Newsletter for Week 36
Updated 09/15/2026-02:09:31 AM
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