| Research Topics: |
| INDEX |
| AI-chat 6 |
| MCS 2 |
| PRIME 42 |
| PRIO 5 |
| aging 10 |
| body 2 |
| brain 9 |
| cancer 7 |
| climate 5 |
| cognition 6 |
| covid-19 4 |
| crime 1 |
| culture 3 |
| dental 1 |
| diabetes 3 |
| diagnostics 1 |
| disease 1 |
| drugs 5 |
| economy 6 |
| exercise 2 |
| eyes 1 |
| genetics 6 |
| gut 1 |
| heart 8 |
| immune 2 |
| language 1 |
| law 2 |
| lyme 1 |
| metabolism 3 |
| microbiome 2 |
| misc 1 |
| nutrition 9 |
| obesity 3 |
| pain 4 |
| physical 2 |
| politics 3 |
| pollution 3 |
| practice 4 |
| psychology 9 |
| quantum 4 |
| religion 1 |
| rights 1 |
| sleep 2 |
| vaccine 1 |
| virus 1 |
|
Scanned: 1729 Evaluated: 336 Selected: 88 Back Issue Map |
| PRIME CANCER | ||||||||
Bmo39-005 | Structural mechanism of Gasdermin E-mediated mtDNA release from apoptotic mitochondria | |||||||
| Quote: | During apoptosis, the permeabilization of the mitochondrial inner membrane (MIM) through still-unclear mechanisms releases mtDNA into the cytosol, triggering the inflammatory cGAS/STING pathway under low caspase activity. Here, we report that, in apoptosis, the active form of the pore-forming protein Gasdermin E (GSDME-N) damages mitochondria before plasma membrane disruption. | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.09.29.755391v1 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Lisa Hohorst Raed Shalaby Nadine Gehle Zakarya Benayad Vincent Z Braun Lars Richter Sina Azami KC Farrell Asma Majoul Shashank Dadsena Eleonora G. Margheritis Christina Kunz Simone Prinz Laurens Wachsmuth Sabine Wilhelm Shirin Kappelhoff Alfredo Cabrera-Orefice Ulrich Brandt Manolis Pasparakis Nieves Peltzer Gerhard Hummer Oezkan Yildiz Katia Cosentino Ana J. Garcia-Saez, | |||||||
| PRIME CANCER | ||||||||
Bmo39-007 | Artificial Intelligence-Driven Nanosensing to Identify Circulating Bacterial DNA: A Novel Approach to Breast Cancer Risk Profiling | |||||||
| Quote: | Pseudomonas aeruginosa, Vibrio parvula, Acinetobacter baumannii, and Streptococcus vestibularis, were considered the most relevant indicators of breast cancer. | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.09.28.755235v1 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Nazim Nazeer Pooja Ratre Vikas Gurjar Olga Goryacheva Santram Lodhi Arpit Bhargava Irina Yu Goryacheva Pradyumna Kumar Mishra, | |||||||
| PRIME CANCER | ||||||||
Bmo39-010 | Thiomorpholino antisense oligonucleotides inhibit telomerase and limit cancer cell proliferation | |||||||
| Quote: | Reactivation of telomerase confers immortality to approximately 90 of human tumors by enabling continuous elongation of the DNA at chromosome ends, or telomeres. The telomerase catalytic subunit TERT adds TTAGGG repeats using a portion of the telomerase RNA component hTR as a template. Because telomerase is inactive in most normal somatic cells, it remains an attractive therapeutic target | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.09.28.754723v1 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Julieta Rivosecchi Arthur J. Zaug Tom Lek Balzs Schfer Marvin H. Caruthers Thomas R. Cech, | |||||||
| CANCER | ||||||||
Mca39-003 | Axitinib in Progressive Metastatic Pheochromocytoma and Paraganglioma: Results of a Phase II Study | |||||||
| Quote: | Conclusions: In patients with progressive metastatic PPGL, single-agent axitinib demonstrated clinically meaningful antitumor activity with a manageable safety profile. The observed efficacy compares favorably with sunitinib in this rare disease. The ability to maintain treatment despite predictable VEGF-associated toxicities suggests that axitinib represents a viable therapeutic option for patients with metastatic PPGL. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.09.28.26364204v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.09.28.26364204v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Jaydira Del Rivero Andrea Apolo Maureen Edgerly William Douglas Figg span classnlm-suffixSr. James Lee John Ausiello Karel Pacak Susan E Bates Tito Fojo, | |||||||
| CANCER GENETICS | ||||||||
Mca39-006 | Somatic and Germline Telomere Biology in Sarcoma: Telomere Maintenance Is Acquired at Liposarcoma Dedifferentiation, and Genetically Longer Telomeres Are Associated With Liposarcoma Risk | |||||||
| Quote: | Conclusion: Sarcoma telomere maintenance is histology-specific and mutually exclusive. In liposarcoma it is acquired at dedifferentiation through focal TERT amplification or ALT and identifies DDLPS with inferior survival. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.09.28.26364135v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.09.28.26364135v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Minggui Pan Joyce Chi Maggie Yuxi Zhou Nam Bui Kristen Ganjoo, | |||||||
| CANCER | ||||||||
Mca39-011 | A serum thyroid hormone metabolite test for molecular diagnostic evaluation of thyroid nodules | |||||||
| Quote: | This study develops a novel molecular blood test of serum THMs for preoperative diagnostic evaluation of thyroid nodules, which displays a high PPV and decent NPV with an excellent overall diagnostic accuracy for DTC. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.09.25.26363992v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.09.25.26363992v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Mengzhe Guo Houfa Geng Qiang Sun Hong Wan Ping Zhou Yongfeng Song Caiyan Zou Xiu Zang Hailin Xi Tian Liao Xuekui Liu Gangshan Peng Yu Wang Mingzhao Xing Jun Liang span classnlm-collab data-hwp-idcollab-1THMs Group, | |||||||
| CANCER | ||||||||
Mga39-003 | Estimating sensitivity from tandem colonoscopy meta-analyses | |||||||
| Quote: | Conclusions WLC sensitivity may be meaningfully lower than previously assumed in CRC screening cost-effectiveness analyses. Modelers should use colonoscopy sensitivity estimates that do not assume a second colonoscopy exam is perfect. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.09.25.26364039v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.09.25.26364039v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Pedro Nascimento de Lima Rachel B Issaka Carolyn M Rutter, | |||||||
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Javilk's Research Links Newsletter for Week 39 Updated 10/03/2026-03:08:04 AM Back Issue Topic Map What interests you? What have you found? Tell me! Drop me a note at Javilk.com to subscribe or submit something. |