| Research Topics: |
| INDEX |
| AI-chat 6 |
| MCS 2 |
| PRIME 42 |
| PRIO 5 |
| aging 10 |
| body 2 |
| brain 9 |
| cancer 7 |
| climate 5 |
| cognition 6 |
| covid-19 4 |
| crime 1 |
| culture 3 |
| dental 1 |
| diabetes 3 |
| diagnostics 1 |
| disease 1 |
| drugs 5 |
| economy 6 |
| exercise 2 |
| eyes 1 |
| genetics 6 |
| gut 1 |
| heart 8 |
| immune 2 |
| language 1 |
| law 2 |
| lyme 1 |
| metabolism 3 |
| microbiome 2 |
| misc 1 |
| nutrition 9 |
| obesity 3 |
| pain 4 |
| physical 2 |
| politics 3 |
| pollution 3 |
| practice 4 |
| psychology 9 |
| quantum 4 |
| religion 1 |
| rights 1 |
| sleep 2 |
| vaccine 1 |
| virus 1 |
|
Scanned: 1729 Evaluated: 336 Selected: 88 Back Issue Map |
| PRIME PRIO AGING HEART | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Aef39-1006 | Old hearts age backwards: transplanted organs adjust to hosts biological age | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: |
What happens to organs when they are transplanted? Hearts from young
donors age rapidly in the bodies of older recipients, and older hearts
are rejuvenated inside young people, according to a study1. The
findings, posted on the preprint server bioRxiv and not yet peer
reviewed, imply that replacement organs could be sourced from older
people than they are at present....
"The remarkable thing is that we found exactly the same effects that we saw in the mice," says Poganik. The transplanted hearts had taken on the biological ages of their new hosts. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Article: | https://www.nature.com/articles/d41586-026-03043-w | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| See Also: |
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PRIME
PRIO
AGING
HEART
| Aef39-1007Multi-omic rejuvenation and life span extension on exposure to youthful circulationQuote: |
Remarkably, this rejuvenation effect persisted even after 2 months of
detachment. Transcriptomic and epigenomic profiles of anastomosed mice
showed an intermediate phenotype between old and young, suggesting a
global multi-omic rejuvenation effect. In addition, old HPB mice showed
gene expression changes opposite to aging but akin to several life
span-extending interventions. Altogether, we reveal that long-term HPB
results in lasting epigenetic and transcriptome remodeling, culminating
in the extension of life span and health span.
| Article:
| https://pubmed.ncbi.nlm.nih.gov/37500973/ | Search Similar: |
Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho
|
HEART
| Sd380-002Atrial Fibrillation Patients Saw 69 Lower Risk with Common Blood ThinnersArticle:
| https://www.sciencedaily.com//releases/2026/09/260925005439.htm | Search Similar: |
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|
HEART
| Sd380-003One CRISPR Treatment Cut Bad Cholesterol in Half for a Full YearQuote: |
A single dose of an experimental CRISPR therapy cut LDL cholesterol and
triglycerides by about half in patients with difficult-to-treat lipid
disorders. The reductions were still present one year later
| Comment:
|
But cholesterol is essential for the brain.
| Article:
| https://www.sciencedaily.com//releases/2026/09/260925005434.htm | Search Similar: |
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|
PRIME
HEART
NUTRITION
| Sd391-007Pomegranate Compound Improves Heart Function by Up to 80 in StudyQuote: |
Researchers at Kings College London found that urolithin A, which is
produced in the body after eating foods including pomegranates, walnuts
and some berries, can help the heart relax more effectively. The
compound also reduced scarring and limited harmful enlargement of the
heart....
| urolithin A activates a protein called PKGl#945;, which plays an important role in blood vessel function and the relaxation of heart muscle. The compound acts on a specific amino acid within the protein, triggering a pathway associated with cardiovascular benefits. In animal models, treatment with urolithin A improved measures of heart function by as much as 80 compared with models that did not receive the compound. Article:
| https://www.sciencedaily.com//releases/2026/09/260925093157.htm | Search Similar: |
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|
PRIME
GENETICS
HEART
| Sd395-002Weak Sunlight Can Still Damage Your DNA, Scientists WarnComment:
|
It isnt just sunlight, we are bombarded by cosmic rays even indoors,
and many other factors killing millions of cells per second. (Most are
blood cells) Yet thanks to evolution, most of us live into our 70s.
| Article:
| https://www.sciencedaily.com//releases/2026/09/260930020324.htm | Search Similar: |
Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | See Also: |
|
HEART
| Sd395-0111 in 13 Adults Under 30 Already Had Hidden Artery PlaqueArticle:
| https://www.sciencedaily.com//releases/2026/09/260929053541.htm | Search Similar: |
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|
AGING
GENETICS
HEART
| Sd395-013Alzheimers Risk Gene APOE4 May Have a Reversible WeaknessQuote: |
The Alzheimers risk gene APOE4 may actively damage brain blood vessels
and sabotage the cellular systems that remove harmful proteins.
Researchers were able to reverse some of these effects in experiments,
revealing promising new targets for Alzheimers, Parkinsons, and other
neurodegenerative
| Article:
| https://www.sciencedaily.com//releases/2026/09/260930225450.htm | Search Similar: |
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Javilk's Research Links Newsletter for Week 39 Updated 10/03/2026-03:08:04 AM Back Issue Topic Map What interests you? What have you found? Tell me! Drop me a note at Javilk.com to subscribe or submit something. |