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CANCER
|
Bcb40-002 | SLC25A28 is a synthetic lethal vulnerability in nucleotide excision repair-deficient cancers |
| Quote: |
Here, we employed a genome-wide CRISPR-Cas9 screen to identify
synthetic lethal vulnerabilities in NER-deficient cancer cells.
|
| Article:
| https://www.biorxiv.org/content/10.64898/2026.10.05.756638v1 |
| Search Similar: |
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| Search Authors: |
Nan Yang Lisa Hoeg Xuechun Bai Sizhi Gao Elisa de Stanchina David Solit Sabine Topka Sami Belhadj Jian Carrot-Zhang Gopa Iyer Daniel Durocher Kent W. Mouw VIJAI JOSEPH Kenneth Offit Steven Lipkin,
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CANCER
|
Bcb40-004 | Establishment and characterization of LNCaP-TR-BoM, a bone metastasis-derived prostate cancer cell line with an intermediate AR-attenuated phenotype |
| Article:
| https://www.biorxiv.org/content/10.64898/2026.10.03.756361v1 |
| Search Similar: |
Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho |
| Search Authors: |
Adrian Chao Xin Lu,
|
|
CANCER
|
Bcb40-006 | p38 MAPK integrates opposing oncogenic APC/-catenin/TCF and GUCY2C tumor-suppressor axes in colorectal cancer |
| Article:
| https://www.biorxiv.org/content/10.64898/2026.10.05.756833v1 |
| Search Similar: |
Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho |
| Search Authors: |
Ariana A Entezari Adi Caspi Jasmine R Alvarez Andrew E Evans Jeffrey A Rappaport Thomas J M Kuret Allison S Doermann Ramkrishna Mitra Adam E Snook Scott A Waldman,
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CANCER
MICROBIOME
|
Bcb40-007 | A microbiota-dependent gut bile acid axis links germline mutant p53 to distal tumour growth. |
| Article:
| https://www.biorxiv.org/content/10.64898/2026.10.05.753853v1 |
| Search Similar: |
Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho |
| Search Authors: |
Noel Wei Yang Ong Nicholas William Fischer Camilla Giovino Paula Rosanna Quaglietta Yoonseo Park Raya Traubici David Malkin,
|
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CANCER
|
Bcb40-008 | Binding kinetics enable tumor-selective MAPK and growth suppression by a Type 1 RAF Inhibitor |
| Quote: |
The combination produced durable regressions across RAS-mutant and
BRAF-mutant models, including a RAS-mutant model refractory to current
therapies, while maintaining favorable tolerability. Thus, we uncover a
generalizable mechanism that enables Type 1 RAF inhibitor plus MEK
inhibitor combinations to achieve tumor-selective MAPK suppression,
with the potential to inform targeted therapy design.
|
| Article:
| https://www.biorxiv.org/content/10.64898/2026.10.05.756774v1 |
| Search Similar: |
Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho |
| Search Authors: |
Mathieu Desaunay Tara Peters Evangelia Matenoglou Beau Baars Bijaya Gaire Ana Orive-Ramos Li ren Joseph P Lyssikatos Michael R. Burkard Dalton Dacus Matthew J. Sale Stuart A. Aaronson Frank McCormick Evripidis Gavathiotis Stefan Gross Poulikos I. Poulikakos,
|
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CANCER
|
Bcb40-010 | A long-term organotypic slice culture model of patient high-grade glioma preserving tumor heterogeneity and architecture, and specificity of CAR T cell targeting |
| Article:
| https://www.biorxiv.org/content/10.64898/2026.10.04.756617v1 |
| Search Similar: |
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| Search Authors: |
Simiao Wang Ching Ouyang Heather N Zook Massimo DApuzzo Hsun Teresa Ku Xiwei Wu Angela S Baker Yue Hao Blake Brewster Michael Berens Behnam Badie Christine E Brown Michael E Barish,
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|
CANCER
|
Bcb40-011 | KRAS-driven metabolic reprogramming of enhanced MFSD2A-mediated lysophosphatidylcholine scavenging promotes survival and progression of pancreatic ductal adenocarcinoma |
| Article:
| https://www.biorxiv.org/content/10.64898/2026.10.05.756824v1 |
| Search Similar: |
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| Search Authors: |
yihui chen Cason Haffner Benson Chellakkan Selvanesan Ranran Wu Riccardo Ballaro Ana Vilchis Celis Mingxin Zuo LaNisha Patterson Michael Adofo Jody Vykoukal Ricardo Leon-Letelier Rongzhang Dou Soyoung Park Yining Cai Daniela Rodriguez-Perera Ehsan Irajizad Florencia McAllister Michael Kim Eugene Koay Brian Wolpin Fu Chung Hsiao Jennifer Dennison Hiroyuki Katayama Vincent Bernard Pagan Anirban Maitra Samir Hanash Johannes Fahrmann,
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CANCER
|
Bcb40-014 | Loss of the Y chromosome drives basal identity and metastatic potential via epigenetic reprogramming in pancreatic cancer |
| Article:
| https://www.biorxiv.org/content/10.64898/2026.10.06.756936v2 |
| Search Similar: |
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| Search Authors: |
Madeleine Dorsch Felix E.G. Beaudry Anna K Baginska Nancy Meyer Anne Petzold Peihua Zhao Belen Otero-Carrasco Kazeera Aliar Sebastian Urban Julia Zummack Jennifer Jung Johanna M. Hlken Ningjun Duan Laura Godfrey Mei-ju M Chen Kathleen Schlter Katyayni Ganesan Florian Over Thomas Kono Hans-Ulrich Schildhaus Katja Steiger Roland Schwarz Elisabeth Hessmann Gnter Schneider Jens T Siveke John P Neoptolemos Teresa Peccerella Maria Llamazares-Prada Alexander Schramm Christoph Plass Florian Rambow Faiyaz Notta Barbara T Grnwald Barbara M Grner,
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CANCER
|
Bcb40-015 | Coordinated alterations in SWI/SNF chromatin remodeling complex, mRNA splicing and mRNA methylation as hallmarks of salivary gland adenoid cystic carcinoma (SACC) |
| Article:
| https://www.biorxiv.org/content/10.64898/2026.10.07.757230v1 |
| Search Similar: |
Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho |
| Search Authors: |
Katarzyna Stawarz Natalia Rusetska Hubert Salamaga Szymon Kubala Irena Paczkowska Pawel Cwiek Alicja Berezowska Maryam Jozghorbani Jakkapong Kluebsoongnoen Magdalena Wilga Susana Poveda Agnieszka Swic Monika Durzynska Adam Galazka Ewa Chmielik Tomasz Rutkowski Andrzej Kawecki Beata Jagielska Piotr Zielenkiewicz Elzbieta Sarnowska Tomasz Jacek Sarnowski,
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CANCER
|
Bim40-017 | Programmable antigen-presenting scaffolds expand rare tumor-antigen-specific T cells from peripheral blood |
| Article:
| https://www.biorxiv.org/content/10.64898/2026.10.05.756899v1 |
| Search Similar: |
Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho |
| Search Authors: |
Jessica Nicole DeVilla Yoav Binenbaum Nicoletta Cieri David KY Zhang Helen Ji Vittoria Martinolli DArcy Giacomo Oliveira Michael Manos Donna Neuberg Jerome Ritz Patrick A Ott David Mooney Catherine J Wu,
|
|
CANCER
|
Bmo40-009 | Lactate epigenetically shapes tumor cell states in H3K27M diffuse midline gliomas |
| Quote: |
Collectively, our findings identify lactate as a key player in the
epigenetic regulation of tumor cell state heterogeneity and suggest
that targeting this pathway offers promise for addressing the
heterogeneous complexities of H3K27M DMGs.
|
| Article:
| https://www.biorxiv.org/content/10.64898/2026.10.02.756321v1 |
| Search Similar: |
Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho |
| Search Authors: |
Joanna Lum Nicholas Nuechterlein Shelby Sliger Sanjana Eyunni Benita Tamrazi Stefan Bluml Wentao Tian Akash Deogharkar Stefan R Sweha Mateus Mota Jill Bayliss Erik Peterson Sunjong Ji Molly Wittwer Ksheetesha Bhat Bryan T. Mott Erin T. Hamanishi Fjodor Merkuri Ana Azambuja Helena Conceicao Fengyun Su Xuhong Cao Rishikesh Pandey Omkar B. Ljare Abhijit Parolia Viveka Nand Yadav Daniel R Wahl Carl Koschmann Marcos Simoes-Costa Kumar Pichumani Shaomeng Wang Arul M. Chinnaiyan Sriram Venneti,
|
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CANCER
|
Mep40-004 | Menopause timing, hormone therapy, epigenetic aging, and breast cancer outcomes: a secondary analysis of the PLCO Cancer Screening Trial |
| Abstract:
| https://www.medrxiv.org/content/10.64898/2026.10.04.26364714v1 |
| Full Text:
| https://www.medrxiv.org/content/10.64898/2026.10.04.26364714v1.full-text |
| Search Similar: |
Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho |
| Search Authors: |
Ting Zhai Vernon S Pankratz Katherine E Zychowski Yafang Li Kimberly K Leslie Yan Guo Christopher I Amos Linda S Cook Shuguang Leng,
|
|
PRIME
CANCER
|
Mep40-015 | Cardiovascular and cancer mortality inversely associated with long-term ambient ultraviolet exposure across US Health Service Areas with UK Biobank corroboration |
| Quote: |
Twelve cancers showed directionally concordant associations across the
datasets, of which ten were inverse. Lung cancer showed the strongest
inverse association in each dataset. CONCLUSIONS Higher UV was
associated with lower cardiovascular and cancer mortality across US
HSAs, with modelled attributable burdens exceeding 5; UK Biobank
findings provided partial corroboration. Twelve of 18 site-specific
cancers were directionally concordant between datasets. US
race-stratified heterogeneity did not follow a skin-colour gradient,
suggesting residual confounding.
|
| Abstract:
| https://www.medrxiv.org/content/10.64898/2026.10.06.26364908v1 |
| Full Text:
| https://www.medrxiv.org/content/10.64898/2026.10.06.26364908v1.full-text |
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| Search Authors: |
John MacMahon Christopher Emig Prue H Hart Benjamin Wang Richard Weller Chris Dibben Andrew Stevenson,
|
|
CANCER
NUTRITION
|
Mep40-020 | Proteomic markers of colorectal cancer risk: results from the European Prospective Investigation into Cancer and Nutrition |
| Quote: |
Conclusion: Colon and rectal cancers have different pre-diagnostic
proteomic profiles, underlining the need for site-specific analyses.
COMP, MIC-1/GDF15, and TFF3 were the most robustly supported biomarkers
of colon cancer risk. Future work should prioritise experimental
validation of these associations and use of repeated measures to define
timing.
|
| Abstract:
| https://www.medrxiv.org/content/10.64898/2026.10.05.26364761v1 |
| Full Text:
| https://www.medrxiv.org/content/10.64898/2026.10.05.26364761v1.full-text |
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Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho |
| Search Authors: |
Matthew A Lee Vivian Viallon David C Muller Ziqiao Wang Neil Murphy James Yarmolinsky Amanda J Cross Pietro Ferrari Paula Jakszyn Mazda Jenab P. Martijn Kolijn Giovanna Masala Domenico Pali Salvatore Panico Ulrike Peters Carlotta Sacerdote Karl Smith-Byrne Ruth C Travis Konstantinos K Tsilidis Rosario Tumino Bethany Van-Guelpen Roel Vermeulen Monique Verschuren Nicholas Wareham Nilanjan Chatterjee Elizabeth Platz Elio Riboli Marc J Gunter,
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CANCER
METABOLISM
|
Mga40-014 | Integrated single-cell and proteomic profiling of pancreatic neoplasia identifies tissue markers that outperform established diagnostic markers in distinguishing cancer from precursor lesions. |
| Abstract:
| https://www.medrxiv.org/content/10.64898/2026.10.02.26364030v1 |
| Full Text:
| https://www.medrxiv.org/content/10.64898/2026.10.02.26364030v1.full-text |
| Search Similar: |
Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho |
| Search Authors: |
Thoa TB Tran Phuong Uyen Nguyen Hoang Duy Truong Pham Johannes Fahrmann Loan Bui Nhat Huy Bui C Max Schmidt,
|
|
CANCER
|
Mhe40-002 | A Multivariable Mixed-Effects Framework for Predicting Disease Progression in Acute Myeloid Leukemia Using Peripheral Hematology, FLT3 Expression, and Patient Compliance |
| Abstract:
| https://www.medrxiv.org/content/10.64898/2026.10.04.26364699v1 |
| Full Text:
| https://www.medrxiv.org/content/10.64898/2026.10.04.26364699v1.full-text |
| Search Similar: |
Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho |
| Search Authors: |
Mohammad Mahdi Amiri Dumar Mitra Aghajani,
|
|
CANCER
|
Mne40-017 | Spatial Neurophysiological Gradients at High Resolution Differentiate Tumor Types in the Human Cortex at the Tumor-Brain Interface |
| Abstract:
| https://www.medrxiv.org/content/10.64898/2026.10.05.26364665v1 |
| Full Text:
| https://www.medrxiv.org/content/10.64898/2026.10.05.26364665v1.full-text |
| Search Similar: |
Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho |
| Search Authors: |
Thomas Nelson Brian Hsueh Peter Hadar Ipsita Das Brian F Coughlin Ayan Mandal Tommy Wilson Emory Peng Andrew Sho Perley Haziq Rabbani Roberto Ciordia Jasmine Zou Alan Bush Matteo Vissani Hazem Ghaith James Cahill Jimmy C. Yang William Munoz Erickson F Torio Adam C. Glaser Joshua D. Bernstock Kelly L. Collins Daniel R. Cleary Harmanpreet K. Tiwana Alexandra J. Golby Pamela S. Jones Bryan D. Choi Brian V. Nahed Ahmed M. Raslan Ziv M. Williams Shadi A. Dayeh Pranav Nanda R. Mark Richardson Wenya Linda Bi Steven Tobochnik Daniel P. Cahill Gavin P. Dunn Sydney S. Cash Angelique C. Paulk,
|
|
CANCER
|
Mpt40-002 | An interpretable cell-centric representation of pancreatic ductal adenocarcinoma matches multiple-instance learning for clinical outcomes and leads to novel pathologist-driven histological biomarkers |
| Abstract:
| https://www.medrxiv.org/content/10.64898/2026.10.03.26364596v1 |
| Full Text:
| https://www.medrxiv.org/content/10.64898/2026.10.03.26364596v1.full-text |
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| Search Authors: |
Maxence Pelloux Catherine TL Tran Jumanah Baig Abdelhakim Khellaf Sally Lang Huang Olivier Tung Nguyen Malle Batardire Sarah-Slim Diwan Zhiyuan Yang Jia-Lin Li Vyky Vu Simon F Roy Genevive Soucy Bich Ngoc Nguyen Basile Tessier-Cloutier Mahdi S Hosseini David JHF Knapp Sverine Valmary-Degano Vincent QH Trinh,
|
|
CANCER
|
Sd402-011 | MIT Scientists Find a Hidden Cancer Risk of the Keto Diet |
| Quote: |
Scientists have increasingly studied whether this metabolic shift
influences other areas of health, including cancer. Previous research
has suggested that ketogenic diets may help protect against colon
cancer. However, new research from MIT points to a very different
outcome in the small intestine, where the same type of diet may
increase cancer risk.
|
| Article:
| https://www.sciencedaily.com//releases/2026/10/261002080037.htm |
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Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho
|
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CANCER
|
Sd405-014 | Stanford Scientists Turn a Cancer Driver Into a Kill Switch |
| Quote: |
Stanford Medicine researchers have developed a two-part molecule that
turns a major driver of B-cell lymphoma against the cancer cells that
depend on it. In mice, twice-daily treatment with the experimental
compound caused aggressive lymphoma tumors to disappear within 11 da
|
| Article:
| https://www.sciencedaily.com//releases/2026/10/261005071533.htm |
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