| Research Topics: |
| INDEX |
| AI-chat 3 |
| MCS 1 |
| PRIME 28 |
| PRIO 3 |
| aging 7 |
| brain 9 |
| brainwave 1 |
| cancer 8 |
| climate 3 |
| cognition 4 |
| covid-19 2 |
| crime 5 |
| culture 3 |
| dental 1 |
| diabetes 3 |
| drugs 2 |
| economy 2 |
| energy 3 |
| exercise 1 |
| eyes 5 |
| gender 1 |
| genetics 5 |
| gut 1 |
| heart 2 |
| immune 5 |
| language 1 |
| metabolism 1 |
| microbiome 2 |
| nutrition 5 |
| obesity 1 |
| pain 1 |
| physical 1 |
| politics 8 |
| population 6 |
| practice 1 |
| psychology 1 |
| quantum 1 |
| reproduction 1 |
| rights 1 |
| sleep 2 |
| tech 1 |
| vaccine 2 |
| war-confl |
| war-cyber 1 |
|
Scanned: 3298 Evaluated: 234 Selected: 59 Back Issue Map |
| MCS PRIME METABOLISM MICROBIOME | ||||||||
Bpt42-015 | Development of CYP8B1-specific inhibitors for metabolic diseases | |||||||
| Quote: | These findings reveal that pharmacologically inhibiting CYP8B1 is able to reshape the BA and gut microbiota profiles and effectively ameliorates metabolic diseases. Overall, CYP8B1-specific inhibitors represent a first-in-class promising, safe and effective therapeutic strategy against metabolic disorders. | |||||||
| Comment: | Low Cytochrome P450, a family of detox enzymes, is known as Porphyria, and leavea a person with a very low tolerance to alcohol, many solvents, and other chemicals as well as sun sensitivity in many people. It is a leading cause of MCS, Multiple Chemical Sensitivities, now also called TILT, Toxic Induced Loss of Tolerance. Chemotherapy is known to cause MCS in many survivors. Antibuse and some medications also cause low Cytochrome P450. Caution is advised. | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.10.20.760253v1 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Zhipeng Fang Alon Roy L. Agua Jennifer Jossart Nisha Sharma Xintian Lyu Zhe Wang Shili Zhang Ji Sun Linsen Shi Juan Ayard Maggie Chang Jiahui Liu Kevin Kou John Shively Adolfo Garcia-Ocana David Horne Holly Yin Lihua Jin J. Jefferson P. Perry Wendong Huang, | |||||||
| PRIME GUT IMMUNE MICROBIOME NUTRITION | ||||||||
Sd421-038 | Scientists Tested 39 Sweeteners and Uncovered Surprising Gut Effects | |||||||
| Quote: | In laboratory experiments involving 39 sweeteners and 25 species of gut bacteria, researchers found that roughly three-quarters of the sweeteners altered the growth of at least one bacterial species. Some slowed or completely stopped the growth of microbes associated with a healthy digestive system. One combination stood out in particular. When the sweetener isosteviol was paired with the antidepressant duloxetine, it strongly suppressed two important gut bacteria involved in maintaining digestive health and regulating blood sugar. The combination also disrupted the balance of a simulated gut microbiome and produced changes that could have implications for inflammation and immune responses. | |||||||
| Article: | https://www.sciencedaily.com//releases/2026/10/261016081103.htm | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
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Javilk's Research Links Newsletter for Week 42 Updated 10/24/2026-02:39:34 AM Back Issue Topic Map What interests you? What have you found? Tell me! Drop me a note at Javilk.com to subscribe or submit something. |