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Aae43-1012

Allulose: The Sweetener That Could Change the Future of Sugar

Quote: D-Allulose Allulose, a generally regarded as safe (GRAS) sugar, is rare in nature. It is among the most promising sweeteners for future use due to its low caloric content, sucrose-like taste, and unique functions. D-Allulose has many physiological effects, such as antiobesity, antihyperglycemia, antidiabetes, anti-inflammatory, antioxidant, and neuroprotective effects. Therefore, D-allulose has important application value in the food, pharmaceutical, and healthcare industries." Frontiers in Microbiology Apr 2022
Article: https://richardgoldberg.substack.com/p/allulose-the-sweetener-that-could
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    DIABETES    KIDNEYS   

Bph43-004

The RNA m6A reader YTHDF2 depletion phenocopies high glucose induced-cellular stress response in diabetic kidney disease

Quote: In corroboration with the above observations in animal and cell line models, independent human DKD transcriptomic datasets demonstrated conserved inflammatory and fibrotic signatures as well as reduced YTHDF2 expression in DKD glomeruli. The YTHDF2 downregulation was found to be inversely correlated with several disease-associated inflammatory and fibrotic genes. Together, these findings identify YTHDF2 dysregulation as a potential post-transcriptional mechanism associated with cellular stress and disease-associated molecular programs in DKD.
Article: https://www.biorxiv.org/content/10.64898/2026.10.23.761296v1
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Search Authors: Harsha Sankar SH Akhilesh Puranik Kaustuv Tripathy Nivedita Singh Anuradha Kesharwani Vipan Parihar Ruthrothaselvi Bharathavikru, 

  Javilk's Research Links Newsletter for Week 43
Updated 10/31/2026-02:16:20 AM
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