| Research Topics: |
| INDEX |
| AI-chat 3 |
| PRIME 33 |
| PRIO 3 |
| aging 9 |
| brain 14 |
| brainwave 1 |
| cancer 12 |
| climate 4 |
| cognition 3 |
| covid-19 1 |
| crime 2 |
| culture 2 |
| dental 2 |
| diabetes 4 |
| drugs 1 |
| economy 4 |
| election 3 |
| energy 2 |
| genetics 9 |
| gut 1 |
| heart 5 |
| immune 6 |
| law 1 |
| metabolism 1 |
| misc 2 |
| nutrition 7 |
| obesity 1 |
| politics 5 |
| pollution 4 |
| practice 1 |
| psychology 3 |
| quantum 2 |
| reproduction 2 |
| rights 1 |
| sleep 1 |
| space 2 |
| tech 4 |
| vaccine 2 |
| virus 3 |
| war-confl |
| war-cyber 1 |
|
Scanned: 3392 Evaluated: 268 Selected: 71 Back Issue Map |
| AGING HEART | |||||||||||||||||||
Bpa44-004 | Pharmacological activation of mitophagy prevents calcific aortic valve disease by targeting dysregulated mitochondrial-to-nuclear communication | ||||||||||||||||||
| Quote: | Conclusions: Mitophagy impairment drives CAVD through dysregulated mitochondrial-to-nuclear communication mediated by the MCL1-PRMT3-BACH1-PARM1 axis. Pharmacological mitophagy activation by TJ0113 corrects this communication and attenuates disease progression, representing a promising therapeutic strategy for CAVD. | ||||||||||||||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.10.31.763012v1 | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Dao Zhou Hanyi Dai Junhao Qiu Yihan Pan Wangxing Hu Hongyu Lu Junhui Xue Haochang Hu Dilin Xu Jingling Dai Jin Lu Shuangshuang Yang Ningjing Qian Yufei Li Si Cheng Ziling Mai Jiaqi Fan Qifeng Zhu Yuchao Guo Yuxin He Jinghai Chen Hongguang Xia Jianan Wang Xianbao Liu, | ||||||||||||||||||
| Search Words: |
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| HEART | |||||||||||||||||||
Bpt44-003 | Long-PDE4D degradation attenuates left ventricular cardiomyocyte hypertrophic remodelling | ||||||||||||||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.10.30.762532v1 | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Aleksandra Judina Zhiyao Shi Jiarong Fu Ivan Sherstnev Veronika Boichenko Jiayue Ling Madihah Hussain Alina Zorn Yuan Yan Sin Houcheng Wang Ao Li Sasha Korogodski Eduardo Torres David Stirling Kyle Chan Cathy Swindlehurst Iyobel Kibread Iain Black Stuart Nicklin George S. Baillie Julia Gorelik, | ||||||||||||||||||
| PRIME HEART | |||||||||||||||||||
Sd430-003 | Scientists Discover a Hidden Driver of High Cholesterol and a Way to Stop It | ||||||||||||||||||
| Quote: | The process begins with a protein known as Ral, which Saltiel had previously investigated in fat cells. The team discovered that consuming high amounts of dietary cholesterol activates Ral, setting off a chain of events that leads to the loss of LDL receptors. As Ral activity increases, fewer receptors remain available to remove harmful cholesterol from the bloodstream. The researchers then identified another critical piece of the mechanism: an enzyme called cathepsin A (CTSA). This enzyme helps drive the process responsible for depleting LDL receptors. When scientists used a small molecule inhibitor to block CTSA, the results were striking. | ||||||||||||||||||
| Article: | https://www.sciencedaily.com//releases/2026/10/261030003003.htm | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| PRIME DIABETES HEART NUTRITION | |||||||||||||||||||
Sd443-009 | Scientists Discover Surprising Heart Benefits of Eating Avocado and Mango Every Day | ||||||||||||||||||
| Comment: | Mango is related to poison ivy and poison oak. It can cause serious stomach irritation and temporary lack of absorption of nutrition. I know this from first hand experience. But Avocados can be quite good. | ||||||||||||||||||
| Quote: | In a study lasting just eight weeks, adults with prediabetes who regularly ate both fruits experienced improvements in blood vessel function and blood pressure, without gaining weight or consuming more calories. | ||||||||||||||||||
| Article: | https://www.sciencedaily.com//releases/2026/10/261031221215.htm | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| AGING HEART NUTRITION | |||||||||||||||||||
Sd443-038 | Experts Say High Blood Pressure Guidelines Are Missing Half the Equation | ||||||||||||||||||
| Quote: | Researchers say that increasing potassium intake, rather than focusing only on reducing sodium, could lead to better blood pressure control. By addressing both nutrients together, this approach could strengthen efforts to prevent hypertension and reduce the risk of serious cardiovascular problems. | ||||||||||||||||||
| Article: | https://www.sciencedaily.com//releases/2026/11/261102075553.htm | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
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Javilk's Research Links Newsletter for Week 44 Updated 11/06/2026-10:26:45 PM Back Issue Topic Map What interests you? What have you found? Tell me! Drop me a note at Javilk.com to subscribe or submit something. |