COVID-19 IMMUNE
Min01-032	Seroprevalence Convergence Does Not Reflect Transmission Equity: Persistent Socioeconomic Disparities in COVID-19 Force of Infection in Canada
	Quote:	Dynamic modelling demonstrates that apparent equity arose from differential amplification of transmission during the Omicron period rather than from elimination of underlying socioeconomic disparities. ... Relative increases were largest in the least deprived quintile 48.5-fold and smallest in the most deprived quintile 31.8-fold
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.01.02.26343363v2
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.01.02.26343363v2.full-text
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	Search Authors:	Abdullah Hassan Emmanuel Issa Nassrallah David N. Fisman,
BRAIN IMMUNE PSYCHOLOGY
Min01-034	Does latent Toxoplasma infection mimic the immune profile of schizophrenia? Sex-specific cytokine and brain-marker alterations suggest partial overlap
	Quote:	Conclusions LT entails neuroinflammatory and neuroimmune alterations that only partly recapitulate schizophrenia; the biomarker pattern and interrelationships differ, arguing against LT as the main driver of schizophrenia-related neuroinflammation.
	Comment:	But has some overlap, which could lead to misdiagnosis when adequ8ate lab tests are not done.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.01.03.26343370v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.01.03.26343370v1.full-text
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	Search Authors:	Jaroslav Flegr Jana Ullmann Filip paniel Jan Toman Martin Hla Blanka ebnkov Jana Petrusov Petr Novotn Josef Velk rka Kakov,
IMMUNE
Mrh01-002	Multicenter international cohort study of HA20 reveals novel genetic architecture and phenotypic evolution
	Quote:	Conclusions HA20 is a common dominantly inherited immune dysregulation disorder with phenotypic heterogeneity and potential age-dependent evolution. This large international cohort highlights diagnostic and therapeutic strategies to advance evaluation and management of HA20.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.01.01.25342105v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.01.01.25342105v1.full-text
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	Search Authors:	Tingyan He Jun Wang Manuel Carpio Tumba Shihao Wang Youyou Luo Jie Chen Guomin Li Zhou Shu Song Zhang Deborah L Stone Yanyan Huang Qianying Lv Wen Xiong Jinbo Wang Zhongxun Yu Charlotte Vera Cuff Elizabeth Kairis Akuti Kethri Atif Towheed Kyr Goyette Urekha Karri Jiebiao Wang Chen Liu Tina Romeo Laia Alsina Manrique De Lara Daniel L Rosenberg Daniel Clemente Juan Carlos Lopez Robledillo Zanhua Rong Xue Zhao Lijun Jiang Juan Carlos Aldave-Becerra Ana Beatriz Muoz-Urribarri Prasad Thomas Oommen Priscilla Campbell-Stokes Meifang Zhu Peng Liu Li Guo Yiping Xu Zihua Yu Huajuan Tong Xiaojian Qiu Yazhi Zhang Hongbo Chen Changming Zhang Junbin Ou Congcong Liu Jinxiang Liu Yunyan Shen Jianshe Cao Xinping Zhang Kangkang Yang Ying Bao Zhijuan Li Jie Cao Yuanhui Duan Fujuan Liu Buyun Shi Min Sun Li Ma Yongxing Chen Wei Yang Xu Han Shuangyue Ma Jie Luo Weiyue Gu Guoliang Yu Weina Shi Ruiqin Zhao Lei Sun Wenhui Li Yunfei An Xuemei Tang Xiaodong Zhao Tongxin Han Jing Ma Yan Li Yurong Piao Fei Sun Dongfeng Zhang Meina Yin Shaoling Zheng Tianwang Li Huizhong Niu Li Lin Shiyue Mei Fang Zhou Sirui Yang Danlu Li Mei Yan Huasong Zeng Ping Zeng Wenjie Zheng Xiaozhong Li Xiaolin Li Yuling Liu Lijuan Huang Haiguo Yu Zhidan Fan Min Shen Meiping Lu Zhihao Fang Casey Allison Rimland Hongmei Song Lance W Peterson Maryam Ali Yousuf Al-Nesf Sami Aqel Dalal Sideeg Mudawi Nikita S Raje Voytek Slowik Julia Harris Brenda Snyder Selma Scheffler-Mendoza Marco Yamazaki-Nakashimada Megan A Cooper Yu Lung Lau Kader Cetin Gedik Wenjie Wang Xiaochuan Wang Amanda K Ombrello Ying Huang Hai-Lin Wu Li Sun Huawei Mao Xiaomin Yu Zhihong Liu Ivona Aksentijevich Daniel L Kastner Daniella M Schwartz Jun Yang Qing Zhou,
PRIME IMMUNE
Mrh01-004	Type I interferon drives dysfunction of a distinct CD8 HLA-DRB1 T cell subset in systemic lupus erythematosus
	Quote:	Conclusion CD8 HLA-DRB1 T cells represent a cytotoxic yet dysfunctional effector memory population expanded in SLE. Type I IFN drives this paradoxical state by promoting exhaustion and impaired degranulation, highlighting a potential therapeutic axis in SLE.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.01.02.26343348v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.01.02.26343348v1.full-text
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	Search Authors:	Huizhong Long Elio Carmona Mikhail G Dozmorov Amr H Sawalha,

Updated weekly. 01/09/2026-11:01:09 PM
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Min01-032

Seroprevalence Convergence Does Not Reflect Transmission Equity: Persistent Socioeconomic Disparities in COVID-19 Force of Infection in Canada

Min01-034

Does latent Toxoplasma infection mimic the immune profile of schizophrenia? Sex-specific cytokine and brain-marker alterations suggest partial overlap

Mrh01-002

Multicenter international cohort study of HA20 reveals novel genetic architecture and phenotypic evolution

Mrh01-004

Type I interferon drives dysfunction of a distinct CD8 HLA-DRB1 T cell subset in systemic lupus erythematosus