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Scanned: 2617 Evaluated: 92 Selected: 33 |
| PRIME BRAIN GENETICS | ||||||||
Mge05-010 | Nonlinear dynamic genetic regulation identifies peripheral drivers of neurodegenerative disease progression | |||||||
| Quote: | xtending 2sGen-GPS to Alzheimers disease, we identified 328 genes linked to cognitive decline and prioritized drug compounds capable of reversing these expression signatures. Our study elucidates how dynamic genetic effects shape the trajectories of NDD-related traits and nominates peripherally accessible, causal genes as promising therapeutic targets for modulating disease progression. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.01.29.26345161v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.01.29.26345161v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Junfeng Luo Hao Wu Wenxuan Du span classnlm-collab data-hwp-idcollab-1the Alzheimers Disease Neuroimaging Initiative Ganqiang Liu, | |||||||
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02/06/2026-07:55:17 PM
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