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Mrh06-002 | NHAPL analysis of glycoRNA reveals sialic acid-containing glycosylated mRNA 3UTRs and enables sensitive SLE diagnostics | |||||||
| Quote: | we identify glycoRNA signatures highly specific to systemic lupus erythematosus SLE. In particular, glycoY5 and glycoU1 achieve near-complete discrimination between patients and healthy controls area under the curve AUC 1.00 and 0.9977, whereas conventional total RNA analysis fails to capture these differences, highlighting RNA glycosylation modification as a distinct regulatory layer. Its simplicity and flexibility make it well suited for clinical glycoRNA profiling and biomarker discovery. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.05.26345357v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.05.26345357v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Jie Gui Meng Zhang Ziwei Kan Xiaojuan He Meipei Gao Jian Han Qiongfang Wang Shengyao Zhang Junyi Hu Wenyi Qin Zi Bi Boyue Huang Zhongjun Wu Jianhua Ran, | |||||||
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02/13/2026-07:20:23 PM
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