| Research Topics: |
| INDEX |
| AI-chat 2 |
| MCS 1 |
| PRIME 26 |
| aging 9 |
| brain 11 |
| brainwave 2 |
| cancer 4 |
| climate 4 |
| cognition 7 |
| covid-19 2 |
| diabetes 2 |
| diagnostics 2 |
| economy 2 |
| eyes 2 |
| genetics 5 |
| heart 2 |
| immune 6 |
| language 1 |
| law 1 |
| lungs 1 |
| metabolism 1 |
| microbiome 1 |
| misc |
| nutrition 4 |
| politics 3 |
| pollution 3 |
| psychology 6 |
| sleep 4 |
| vaccine 1 |
| virus 2 |
|
Scanned: 2653 Evaluated: 237 Selected: 57 |
| PRIME NUTRITION | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Aaa07-001 | Coffee and Tea Reduces Dementia Risk | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | In a new study published in the February 9, 2026 edition of the journal JAMA researchers concluded: Greater consumption of caffeinated coffee and tea was associated with lower risk of dementia and modestly better cognitive function, with the most pronounced association at moderate intake levels. The objective of this study was to investigate associations of coffee and tea intake with dementia risk and cognitive function. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Comment: | I, and some other medical researchers whom I know, have seen firsthand that there is a cognitive decline from caffein rich drinks. This is more noted in the creative arts, such as programming, where caffein eliminates many of the peripheral and "out of box" ideation so essential for good creative work. Other health people question coffee and advise against coffee for health related reasons. And mostimportant, do NOT use Styrofoam cups. What you choose to do is up to you. We are just providing information for you to use in deciding what you wish to do, and perhaps justify your actions. As the saying goes, your mileage may vary. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Article: | https://richardgoldberg.substack.com/p/coffee-and-tea-reduces-dementia-risk | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PRIME NUTRITION | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Aaa07-003 | Certain bitter foods may trigger a brain response similar to working out, study finds | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | The key finding of this experiment is that it first demonstrated how flavanol intake stimulation likely the bitter taste is transmitted to the central nervous system, triggering a stress response reaction that enhances short-term memory and produces beneficial effects on the circulatory system, professor Naomi Osakabe of Shibaura Institute of Technology in Japan told Fox News Digital | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Article: | https://www.foxnews.com/health/certain-types-food-may-boost-brainpower-memory-scientists-say | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PRIME DIABETES | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mdb07-026 | Longitudinal Proteogenomic Analysis Reveals Mechanistic Insights into the Progression from Prediabetes to Type 2 Diabetes | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | Mediation analysis revealed 60 putative causal links connecting allele-driven plasma protein expression to clinical traits, identifying body fat distribution, insulin resistance, and #946;-cell function as central drivers of pathogenesis. Collectively, these findings highlight specific proteins underlying disease progression and substantiate the view that prediabetes and T2D are not distinct conditions, but rather stages on a unified metabolic spectrum. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.13.26346161v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.13.26346161v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Authors: | Archit Singh Marlene Ganslmeier Mauro Tutino Young-Chan Park Jrgen Machann Fritz Schick Andreas Peter Rainer Lehmann Yiying Wang Yurong Cheng Leontine Sandforth Sebastian Schuth Jochen Seissler Nikolaos Perakakis Peter E. H. Schwarz Julia Szendrdi Robert Wagner Michele Solimena Annette Schrmann Stefan Kabisch Andreas F. H. Pfeiffer Stefan R. Bornstein Matthias Blher Norbert Stefan Andreas Fritsche Hubert Preissl Reiner Jumpertz von Schwartzenberg Martin Hrabe de Angelis Michael Roden Ozvan Bocher Eleftheria Zeggini Andreas L. Birkenfeld, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PRIME DIAGNOSTICS | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mga07-002 | Glutamate Dehydrogenase as a Superior Biomarker for Choledocholithiasis Risk Stratification | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | Conclusion: GLDH outperforms AST, ALT and bilirubin as a screening and predictive marker for CDL, supporting its inclusion in clinical guidelines for risk stratification. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.14.26346323v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.14.26346323v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Authors: | Jan P Sutter Lorenz Kocheise Soleman Almadok Jan Drews Franziska Stallbaum Jan Kempski Hannno Ehlken Hans Pinnschmidt Marcel Seungsu Maurice Schueckens Giulia Heide Lorenz Adlung Julian Schulze zur Wiesch Samuel Huber Ansgar W. Lohse, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Words: |
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| PRIME AGING BRAIN | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mgr06-004 | Associations of amyloid biomarkers with brain and cognitive changes from imaging, spinal fluid, and plasma | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | DISCUSSION Using different measurement methods, amyloid was not consistently associated with volumetric or cognitive measures. Our findings also suggest that plasma markers may not be associated with cognitive and brain changes in the same manner as CSF and PET. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.05.26345647v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.05.26345647v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Authors: | Jason Scully Mahsa Dadar Cassandra Morrison span classnlm-collab data-hwp-idcollab-1the Alzheimers Disease Neuroimaging Initiative, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PRIME EYES | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Min06-006 | Comparative Analysis of Biofilm Formation in Bacterial and Fungal Isolates from Contact Lens and Non-Contact Lens Associated Keratitis | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | Pseudomonas aeruginosa, known for strong biofilm production and high multidrug resistance. In contrast, NCLAK showed a higher incidence of fungal infections, particularly Candida albicans. The results highlight the significance of early diagnosis, tailored and improved awareness regarding contact lens hygiene to prevent complications associated with keratitis. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.09.26345896v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.09.26345896v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Authors: | Kavin Shilpa Abraham Sujith Sri Surya Ravi Leela Kagithakara Vajravelu, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Words: |
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| PRIME AGING | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mne06-006 | Predictive Value of Plasma P-tau217 and APOE Genotype for Preclinical Cognitive Decline in Alzheimers Disease | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | Conclusions Plasma P-tau217 levels and the presence APOE genotype can be used to estimate the interval before the onset of overt cognitive impairment and the diagnosis of AD. The findings here support the use of commercially available APOE genotyping and plasma P-tau217 to determine optimal timing for therapeutic intervention, particularly during the preclinical phase of the disease. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.06.26345774v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.06.26345774v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Authors: | Yuexuan Xu Tamil Iniyan Gunasekaran Yian Gu Dolly Reyes-Dumeyer Angel Piriz Danurys Sanchez Diones Rivera Mejia Martin Medrano Rafael A. Lantigua Lawrence Honig Rachael Wilson Ramiro Eduardo Rea Reyes Jennifer J Manly Adam M. Brickman Corinne D. Engelman Sterling Johnson Sanjay Asthana David A. Bennett Melissa Petersen Sid OBryant Badri N. Vardarajan Richard Mayeux, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PRIME AGING BRAIN | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mne06-008 | The prognostic value of blood-based p-tau217 levels on progression to clinical impairment | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | Elevated p-tau217 associated with accelerated cognitive decline, both independent of, and synergistic with, greater A#946;-PET. These findings establish plasma p-tau217 as a robust prognostic marker in preclinical AD and support its value in future individualized risk prediction. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.06.26345770v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.06.26345770v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Authors: | Rachel F. Buckley Diana L. Townsend Colin J. Birkenbihl Madison Cuppels Gillian T. Coughlan Mabel T. Seto Jane A. Brown Michael J. Properzi Merle C. Hnig Annie Li Aaron P. Schultz Jasmeer Chhatwal Hyun-Sik Yang Steven Arnold Pia Kiviskk Bryan D. James Sid OBryant Robert A. Rissman Melissa Petersen Jessica Z. K. Caldwell Tobey Betthauser Julie Elisabeth Oomens Maria Carrigan Brian Healy Jorge Garcia Condado Sterling Johnson Wai-Ying Wendy Yau Oliver Langford Michelle Farrell Rebecca E. Amariglio Dorene M. Rentz Kathryn V. Papp Timothy J. Hohman Michael Donohue Paul S. Aisen Keith A. Johnson Reisa A. Sperling, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PRIME SLEEP | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mne07-002 | Local REM sleep-N1-wake sleep stage mixing in narcolepsy type 1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | The predominance of stage mixing in frontal and central regions, areas typically associated with executive and motor control, may contribute to the partial preservation of awareness during dissociated REM phenomena. Further, self-reports of hypnagogic hallucinations correlated best with dissociations involving occipital locations, in agreement with its usual visual content. Coherence analysis was also conducted but did not reveal additional insight. These results suggest that orexin deficiency destabilizes REM sleep organization across cortical projection area contributing both to REM sleep dissociation and to abnormal state transitions observed in NT1. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.14.26346110v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.14.26346110v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Authors: | Constantin Weberpals Adrien Specht Natasja Bonde Andersen Mads Olsen Yves Dauvilliers Giuseppe Plazzi Lucie Barateau Fabio Pizza Francesco Biscarini Jing Zhang Han Yan Ambra Stefani Birgit Hogl Matteo Cesari Seung Chul Hong Dmitri Volfson Poul Jennum Andreas Brink-Kjaer Emmanuel Mignot, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PRIME AGING COGNITION | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mne07-038 | Bilingualisms protective effects in Alzheimers disease: Mechanisms of resilience and resistance | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | DISCUSSION The protective effects of bilingual experience may engage both resilience and resistance to AD pathophysiology mechanisms. These results underscore the importance of capturing bilingualism in aging cohorts and the study of how lifestyle and sociocultural factors shape the biological expression of neurodegenerative disease. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.13.26345903v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.13.26345903v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Authors: | Wenfu Bao Stephanie M. Grasso Isabel Sala M. Beln Snchez-Saudins Judit Selma-Gonzlez Javier Arranz Nuole Zhu Sara Rubio-Guerra igo Rodrguez-Baz Mara Carmona-Iragui Isabel Barroeta Ignacio Illn-Gala Juan Fortea Olivia Belbin Ldia Vaqu-Alczar Marco Calabria Eider M. Arenaza-Urquijo Alexandre Bejanin Daniel Alcolea Alberto Lle Miguel ngel Santos-Santos, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PRIME NUTRITION SLEEP | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mnu07-022 | Poor Sleep Health Traits Influence Liking of Sweet Foods and Sugary Food Intake: A UK Biobank Study | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | Poorer sleep health, particularly evening chronotype and daytime sleepiness, was associated with greater sweet liking and higher free sugar intake, with sweet liking partially mediating associations between sleep traits and sugar consumption. Sweet-taste liking may represent an underexamined pathway linking sleep/circadian disruption to free sugar intake. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.15.26346360v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.15.26346360v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Authors: | Phoebe SC Hui Calista D Touw Surabhi Bhutani Liang-Dar Hwang, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PRIME AGING COGNITION HEART | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mph06-002 | A Novel Drug-Drug Interaction: Dihydropyridine Calcium Channel Blockers Amplify Gabapentin-Associated Dementia Risk | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | Conc: Conclusions We identified a novel drug-drug interaction whereby DHP CCB co-medication amplifies gabapentin-associated dementia risk, confirmed by time-varying analysis Rate Ratio1.65. The DHP-specific signal is biologically plausible given independent evidence that DHP CCBs may adversely affect cognition DREAM consortium, while the absence of interaction with verapamil aligns with its potential neuroprotective properties identified in drug repurposing studies. The F03-specific pattern suggests drug-induced cognitive impairment that may be reversible. These hypothesis-generating findings identify gabapentin-DHP CCB combinations as a target for cognitive safety monitoring and warrant confirmation with concurrent exposure measurement | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.06.26345763v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.06.26345763v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Authors: | James W Green Suril Gohel Barbara Tafuto Luciana Mascarenhas Fonseca Michal Schnaider Beeri Sharon Sanz Simon James Scott Parrott Branimir Ljubic Michael Schulewski, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PRIME BRAINWAVE COGNITION | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mpy06-008 | Abnormal hippocampo-cortical theta-gamma phase-amplitude coupling in Alzheimers disease | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | INTRODUCTION Cognitive decline in Alzheimers disease AD may arise not only from neuronal loss but also from disrupted temporal coordination across distributed networks. Prior works in healthy individuals has shown memory-related modulation of hippocampalcortical phaseamplitude coupling PAC. We hypothesized alteration of resting-state hippocampo-cortical PAC in AD which relates to cognitive impairment. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.06.26345635v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.06.26345635v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Authors: | Erfan Baradarantohidi Srikantan Nagarajan Kamalini Ranasinghe Stefan Haufe, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PRIME AGING BRAIN COGNITION PSYCHOLOGY | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mpy06-020 | Functional MRS uncovers age-related alterations in cerebral lactate dynamics during emotional-cognitive engagement, revealing metabolic vulnerability in the dACC | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | Introduction Lactate plays dual roles in neuronal energy metabolism and signalling. The dorsal anterior cingulate cortex dACC, a region with high baseline glycolytic activity implicated in psychiatric disorders, may exhibit dynamic lactate responses to graded cognitive-emotional demands. Because mitochondrial function declines with age, aging may model whether fMRS-derived lactate dynamics can detect latent neurometabolic vulnerabilities. ... establishes a metabolic stress-testing paradigm for detecting latent neuroenergetic vulnerabilities, supporting fMRS utility for probing mitochondrial function in health and psychiatric disorders. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.05.26345665v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.05.26345665v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Authors: | Edward Caddye Joel Patchitt Anouk Schrantee William T Clarke Itamar Ronen Alessandro Colasanti, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| AI-CHAT PRIME PSYCHOLOGY | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mpy07-026 | Reproducible symptom subtypes of depression identified using unsupervised machine learning | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | Clusters aligned with the existing clinical subtypes, atypical and melancholic depression, alongside other potentially novel clusters reflecting a range of different symptom profiles. Atypical clusters hypersomnia with weight gain appeared in both Q1 and Q2 and were associated with younger age and higher body mass index. Distinct clusters combining insomnia, weight gain, and having thoughts of death were associated with asthma, suggesting potential inflammatory dysregulation. Further clusters were characterised by psychomotor changes and showed strong associations with Parkinsons disease, both before and after the mental health questionnaire was conducted. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.13.26346271v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.13.26346271v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Authors: | David M. Howard Francisco Diego Rabelo-da-Ponte Maria Viejo-Romero Evangelos Vassos Cathryn M. Lewis, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| MCS PRIME IMMUNE | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mrh06-002 | NHAPL analysis of glycoRNA reveals sialic acid-containing glycosylated mRNA 3UTRs and enables sensitive SLE diagnostics | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | we identify glycoRNA signatures highly specific to systemic lupus erythematosus SLE. In particular, glycoY5 and glycoU1 achieve near-complete discrimination between patients and healthy controls area under the curve AUC 1.00 and 0.9977, whereas conventional total RNA analysis fails to capture these differences, highlighting RNA glycosylation modification as a distinct regulatory layer. Its simplicity and flexibility make it well suited for clinical glycoRNA profiling and biomarker discovery. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.05.26345357v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.05.26345357v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Search Authors: | Jie Gui Meng Zhang Ziwei Kan Xiaojuan He Meipei Gao Jian Han Qiongfang Wang Shengyao Zhang Junyi Hu Wenyi Qin Zi Bi Boyue Huang Zhongjun Wu Jianhua Ran, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PRIME IMMUNE | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mrh06-004 | Pan-disease blood protein profiles of rheumatic autoimmune diseases | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | Systemic autoimmune rheumatic diseases SARDs are a heterogeneous group of autoimmune conditions characterized by immune system dysregulation leading to chronic inflammation and tissue damage. The overlapping clinical manifestations make differential diagnosis challenging, ... This explorative cross-sectional study demonstrates the importance of a pan-disease approach to biomarker identification within and between the five SARDs. NPX boxplots from this study are available open-access through the Human Protein Atlas, facilitating further plasma-proteome research on autoimmune diseases. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.05.26345462v1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.05.26345462v1.full-text | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Search Authors: | Josefin Kenrick Charlotta Preger Mara Bueno lvez Alejandra Ulloa Gran Bergstrm Antonella Notarnicola Begum Horuluoglu Anna Smed-Srensen Anna Frnert Anna Norrby-Teglund Iva Gunnarsson Marie Wahren-Herlenius Marie Holmqvist Leonid Padyukov Karine Chemin Lina Marcela Diaz-Gallo Ingrid E. Lundberg Elisabet Svenungsson Vivianne Malmstrm Lars Klareskog Sofia Bergstrm Mathias Uhln Peter Nilsson Fredrik Edfors Elisa Pin, | |||||||||||||||||||||||||||||||||||||||||||||||||||
| PRIME CANCER POLLUTION | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Zaa07-003 | The Wi-Fi and Mobile Phone Cancer Debate Heats Up | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | Only one of these 12 reviews was considered by experts from the International Commission on the Biological Effects of Electromagnetic Fields ICBE-EMF to be well-executed, and this was the one by Mevissen et al., which concluded that there is high certainty evidence that RF-EMF exposure increases the incidence of malignant schwannomas heart tumours and gliomas brain tumours in rats, with moderate certainty evidence of an increased risk of rare tumours in the adrenal glands and in the liver. This RF-EMF is just the same type of radiation that is emitted by your phone and that you hold to your head and keep in your pocket, and that is constantly by your side. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Comment: | And the World Health Organization wanted t odilute that finding as much as possible. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Article: | https://principia-scientific.com/the-wi-fi-and-mobile-phone-cancer-debate-heats-up/ | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| PRIME LAW | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Zab07-004 | Oklahoma Lawmakers Introduce Measures to Bar Sharia Law in Courts and Restrict Foreign Influence | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | Responding to critics who have raised concerns about religious liberty, Woolley told Breitbart News, While we recognize that Americans enjoy freedom of religion, this resolution is a step to protect homeland security and Oklahomans constitutional rights rights that Islam and Sharia law do not adhere to. Sharia law is a political ideology presented as a religion. It is a Trojan horse used to infiltrate free and independent nations, such as America, in order to overthrow them and instill and expand Sharia law principles. Hamilton said to Breitbart News, ?This is America? In order to own a piece of it, you should be an American. To allow any foreign entity to own a piece of America is treasonous.? | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Comment: | Remember, Islam seeks to disenfranchise and subjugate all women. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Article: | https://www.breitbart.com/politics/2026/02/17/exclusive-oklahoma-lawmakers-introduce-measures-to-bar-sharia-law-in-courts-and-restrict-foreign-influence/ | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| AI-CHAT PRIME CLIMATE | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Zza07-000 | Metas Internal Tests Reveal AI Failed Child Safety Checks | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | Expert witness Damon McCoy, a professor at New York University, testified about Metas internal red-teaming results after reviewing documents the company provided during the discovery phase of the litigation. According to the internal report presented in court, Meta tested its chatbot product across three critical safety categories. The results showed significant failures across all three areas. In the child sexual exploitation category, the product demonstrated a failure rate of 66.8 percent. For sex-related crimes, violent crimes, and hate content, the failure rate reached 63.6 percent. Even in the suicide and self-harm category, the product failed to provide adequate protection 54.8 percent of the time. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Article: | https://www.breitbart.com/tech/2026/02/17/new-mexico-lawsuit-metas-internal-tests-reveal-ai-failed-child-safety-checks/ | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| PRIME CLIMATE | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Zza07-001 | Prime Trigger of Ice Ages is Milankovitch Cycles forget CO2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | CO#8322; is not the driver, nor does it initiate warming. There is an 800 to 1,100-year time lag from warming oceans to rising CO#8322; levels. The oceans warm entirely due to natural variabilityincluding the sun, landforms, orbital anomalies, oceanic currents, water vapor dispersion, prevailing winds, and storms. This natural warming cycle releases soluble chemicals like CO#8322; back into the atmosphere via Henrys Law, based on a temperature-dependent equilibrium. The oceans contain 86 of the worlds surface carbon, while the atmosphere is a carbon desert containing only 1-2. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Article: | https://principia-scientific.com/prime-trigger-of-ice-ages-is-milankovitch-cycles-forget-co2/ | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| PRIME CLIMATE | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Zza07-002 | Using Data To Show CO2 Does NOT Drive Temperature | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | These events contrast with the lack of any change in the accelerating rate of increase of CO2 during the reduction of economic activity from the 2019 pandemic or the current Net Zero effort negating the claim that CO2 has been increasing due to the human activities. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Article: | https://principia-scientific.com/using-data-to-show-co2-does-not-drive-temperature/ | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| PRIME CLIMATE | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Zza07-004 | Forget Gloom and Doom: Ten Surprising Benefits of a Warmer, CO#8322;-Richer World | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | But carbon dioxide is not poison. Its the gas animals exhale and plants inhale, the raw material of photosynthesis. And a warmer world doesnt erase life; it shifts it. There are real risks from rapid climate change. Those are well covered in everything from scientific papers to hysterical media stories. What isnt covered nearly as often are the measurable upsides already visible in the data. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Article: | https://pjmedia.com/jamie-wilson/2026/02/19/forget-gloom-and-doom-ten-surprising-benefits-of-a-warmer-co-richer-world-n4949694 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| PRIME ECONOMY POLITICS | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Zza07-007 | Treasury Secretary Bessent Reacts to Supreme Court Tariff Decision | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | This administration will invoke alternative legal authorities to replace the IEEPA tariffs. We will be leveraging Section 232 and Section 301 tariff authorities that have been validated through thousands of legal challenges. Treasurys estimates show that the use of Section 122 authority combined with potentially enhanced Section 232, and Section 301 tariffs, will result in virtually unchanged tariff revenue in 2026. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Comment: | The court did not rule against the use of tariffs, only against the use of the Emergency Act to justify the tariffs, and said the Supreme Court was arguably the wrong court to decide this. Tariffs remain a MAJOR negotiating point Trump has been using | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Article: | https://redstate.com/wardclark/2026/02/20/new-treasury-secretary-bessent-reacts-to-supreme-court-tariff-decision-n2199390 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| PRIME ECONOMY LANGUAGE POLITICS | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Zza07-008 | Justice Clarence Thomas Issues Blistering Dissent in Tariff Case Following Trump Loss | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | I join Justice Kavanaughs principal dissent in full, Thomas began. As he explains, the Courts decision today cannot be justified as a matter of statutory interpretation. Congress authorized the president to regulateimportation. Moreover and here lies the key throughout American history, the authority to regulate importation has been understood to include the authority to impose duties on imports. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Article: | https://www.westernjournal.com/breaking-justice-clarence-thomas-issues-blistering-dissent-tariff-case-following-trump-loss/?ff_sourceredirect | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| PRIME POLITICS | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Zzb07-016 | The Shattered Dreams of Steve Bannon the Wannabe Savior of the MAGA Movement | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Quote: | In dozens of messages, Bannon advises Epstein on how to navigate the fallout, writing in April 2019: first we need to push back on the lies; then crush the pedo/trafficking narrative ; then rebuild your image as philanthropist. ... Steve Bannon has nothing to do with me or my Presidency, Trump said. When he was fired, he not only lost his job, he lost his mind. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Comment: | Trump may be wrong, it was likely long before he was fired. | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Article: | https://pjmedia.com/scott-pinsker/2026/02/20/the-shattered-dreams-of-steve-bannon-the-wannabe-savior-of-the-maga-movement-n4949744 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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02/20/2026-11:39:18 PM
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