Research
Topics:
INDEX
AI-chat 1
PRIME 12
aging 6
body 1
brain 7
cancer 5
cognition 2
covid-19 2
culture 2
dental 2
diabetes 1
diagnostics 1
disease 3
genetics 5
heart 8
herbs 1
immune 2
kidneys 2
language 1
lungs 4
metabolism 1
nutrition 2
obesity 1
pain 3
physical 1
politics 2
pollution 1
practice 2
privacy 2
psychology 5
religion 1
reproduction 2
rights 2
sleep 1
vaccine 1
virus 4
 
Scanned: 2578
Evaluated: 292
Selected: 56

 
    PRIME    AGING    HEART   

Mcr10-030

Effect of age, sex and BMI on resting ECG intervals and their variabilities in healthy adults

Quote:Conclusion Age, BMI, and sex all have major impacts on the ECG intervals and their variability. A resting heart behaves largely like a pulse width modulation system, with a stable active interval and an adjustable idle interval to meet the varying needs for cardiac output. The durations and variabilities of the active interval, more than those of the RR interval, are indicators of a hearts health condition. A young and healthy heart tends to have a shorter duration and smaller variability in the active interval.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.07.26347862v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.07.26347862v1.full-text
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Search Authors: Qihou Zhou, 
    AGING   

Mep10-030

Multimodal Ageing Biomarkers and Plasma Proteomic Signatures Associated with All-Cause Mortality

Abstract: https://www.medrxiv.org/content/10.64898/2026.03.09.26347914v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.09.26347914v1.full-text
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Search Authors: Maira Pyrgioti Ines Mesa Eguiagaray Paul Redmond Janie Corley Mark E Bastin Maria Valdes Hernandez Tom C Russ Joanna M Wardlaw Eilis Hannon Ian J Deary Keenan A Walker Elliot M Tucker-Drob Simon R Cox Riccardo E Marioni Sarah E Harris, 
    AGING    BODY   

Mgr10-002

Walking in the Free World: Establishing Normative Trajectories for Ecological Assessment of Robust Gait Variability with Age

Quote:Leveraging these metrics, we established the normative trajectory and reference values of real-world gait variability across the ageing lifespan, revealing a distinct, age-dependent increase in spatio-temporal fluctuations, indicating a decline in rhythmicity and steadiness with age.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.06.26347806v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.06.26347806v1.full-text
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Search Authors: Kai Zhe Tan Kreimir Friganovi Yong Kuk Kim Angela Frautschi Michelle Gwerder Kok Yang Tan Vanessa Jean Wen Koh Rahul Malhotra Angelique Wei-Ming Chan David B. Matchar Navrag B. Singh, 
    AGING    PHYSICAL   

Mgr10-004

Ability to Detect Changes and Minimal Important Difference of Real-World Digital Mobility Outcomes in Proximal Femoral Fracture Patients

Quote:Conclusions For the first time, MIDs are presented for real-world DMOs in PFF patients. These MIDs inform sample size requirements and interpretation of intervention effects for clinical trials, thereby providing guidance and reassurance for clinicians and regulatory bodies. ... MIDs for walking speed were between 0.04 m/s and 0.08 m/s, and MIDs for cadence between 4 and 6 steps/minute.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.06.26347770v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.06.26347770v1.full-text
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Search Authors: C-P Jansen J Braun P Alvarez MA Berge H Blain J Buekers B Caulfield A Cereatti S Del Din J Garcia-Aymerich JL Helbostad J Klenk S Koch E Murauer A Polhemus L Rochester B Vereijken MA Puhan C Becker A Frei, 
Search Words:
Digital Mobility Outcomes DMOs Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Minimal Important Difference MID Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
proximal femoral fracture PFF. Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    AGING    PAIN   

Mob10-026

Beyond staging: Potentially divergent trajectories of pain, quality of life, and fertility in endometriosis - prospective observational cohort study.

Quote:Conclusions Pain severity, quality-of-life impairment, and reproductive dysfunction in endometriosis represent partially independent dimensions of disease activity. While neuroinflammatory mechanisms appear to drive pain and quality-of-life impairment, fertility outcomes and organ-threatening complications are primarily determined by structural disease burden. Integrating anatomical staging with multidimensional symptom assessment and molecular profiling may enable more personalized management strategies for women with endometriosis.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.09.26347925v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.09.26347925v1.full-text
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Search Authors: Michael Fanta Zdenka Lisa Kristyna Hlinecka Michal Mara Radoslav Janostiak, 
    AGING    GENETICS   

Mpt10-004

Identifying Single-Nucleotide Polymorphisms Intersecting Alzheimers Disease Pathology and End-of-Life Traits Using Genomic Informational Field Theory GIFT

Quote:These results demonstrate that rethinking analytical representation, rather than solely increasing sample size, can expand discovery potential of genetic association studies, offering a transparent and complementary framework for quantitative genomics in deeply phenotyped datasets.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.05.26347710v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.05.26347710v1.full-text
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Search Authors: Sam Heysmond Panagiota Kyratzi Jonathan Wattis Andras Paldi Keeley J Brookes Karim Kreft Beili Shao Cyril Rauch, 

  Javilk's Research Links for Week 10
Updated 03/15/2026-01:54:15 AM
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