| Research Topics: |
| INDEX |
| AI-chat 5 |
| PRIME 22 |
| aging 12 |
| brain 10 |
| brainwave 1 |
| cancer 8 |
| climate 2 |
| cognition 6 |
| covid-19 3 |
| crime 3 |
| culture 1 |
| dental 1 |
| diabetes 8 |
| disease 3 |
| economy 1 |
| genetics 8 |
| heart 5 |
| immune 5 |
| kidneys 5 |
| language 1 |
| metabolism 1 |
| misc 1 |
| nutrition 5 |
| pain 3 |
| physical 3 |
| politics 3 |
| pollution 1 |
| practice 3 |
| privacy 5 |
| psychology 8 |
| reproduction 4 |
| rights 2 |
| sleep 1 |
| unk |
| war-confl |
|
Scanned: 2683 Evaluated: 284 Selected: 75 |
| PRIME POLLUTION PSYCHOLOGY | |||||||||||||||||||
Zzb13-008 | Bisphenol a exposure and major depressive disorder: an integrative analysis combining network toxicology, molecular docking, genetic epidemiology, and transcriptomic validation | ||||||||||||||||||
| Quote: | A total of 571 shared targets between BPA and MDD were identified, enriched in pathways related to neurodevelopment, synaptic plasticity, and cognitive function. Six core targets ESR1, SRC, EGFR, AKT1, PLCG2, and JAK3 were highlighted. MR and SMR analyses supported causal roles for AKT1, SRC, PLCG2, and JAK3 in MDD, whereas EGFR exhibited a protective effect. These findings provide integrative evidence for molecular mechanisms underlying BPA-associated susceptibility to MDD and identify potential targets for future therapeutic intervention. | ||||||||||||||||||
| Article: | https://www.nature.com/articles/s41398-026-03862-5 | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Words: |
| ||||||||||||||||||
|
Javilk's Research Links for Week 13 Updated 04/04/2026-01:13:07 AM What interests you? What have you found? Tell me! Drop me a note to subscribe or submit something. |