Research
Topics:
INDEX
AI-chat 7
PRIME 20
aging 5
brain 8
cancer 12
climate 3
cognition 5
covid-19 2
crime 2
dental 2
diabetes 6
disease 2
economy 3
eyes 1
gender 1
genetics 7
heart 6
kidneys 1
language 1
lungs 2
metabolism 4
microbiome 1
nutrition 7
obesity 1
pain 4
physical 1
politics 2
pollution 1
privacy 1
psychology 7
radiation 1
reproduction 4
rights 1
sleep 1
soc-media
stress 1
virus 2
war-confl
 
Scanned: 1426
Evaluated: 167
Selected: 66

 
    PRIME    CANCER    NUTRITION   

Aab14-001

A common nutrient could supercharge cancer treatment

Quote: Researchers at the University of Chicago have uncovered a surprising new role for zeaxanthin, a plant-based compound best known for supporting eye health. According to findings published in Cell Reports Medicine, this common carotenoid may also help the immune system fight cancer by enhancing the activity of key immune cells. The discovery points to zeaxanthin as a simple, widely available supplement that could improve how well cancer immunotherapies work.
Article: https://www.sciencedaily.com/releases/2026/04/260410083114.htm
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    PRIME    CANCER    POLLUTION   

Aac14-000

EPA Failed to Warn Public of Pesticide Cancer Risks Even When Agency Found High Risk

Quote: But if the agency is going to allow such chemicals to be freely sold at Home Depot, Wal-Mart and farm-supply stores, the very least theThe analysis found that pesticides have been allowed on the market with a cancer risk as high as 1 in every 100 people exposed, a far greater level than the EPAs benchmark of a 1 in a million chance of developing cancer. Over the last 40 years, the EPA has approved 200 active ingredients that are likely or possible carcinogens....

EPA must do is require a clear cancer warning on the label. Warnings save lives by incentivizing users to wear protective equipment that reduces risk.

Article: https://principia-scientific.com/epa-failed-to-warn-public-of-pesticide-cancer-risks-even-when-agency-found-high-risk/
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    CANCER   

Mca14-004

Cell-free chromatin epigenomic profiling enables non-invasive pancreatic cancer cell-state identification

Abstract: https://www.medrxiv.org/content/10.64898/2026.04.02.26349987v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.04.02.26349987v1.full-text
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Search Authors: Karl Semaan Marc Eid Damien Vasseur Gunsagar S. Gulati Cibelle Lima Elio Ibrahim Ji-Heui Seo John J. Canniff Hunter Savignano Alexander Jordan Leigh Culane Noa Philips Rashad Nawfal Aislyn Schalck Andressa Dias Costa Elizabeth A. Andrews Emma C. Coleman Talal El Zarif Garyoung Gary Lee Razane El Hajj Chehade Ze Zhang Gaelle Nafeh Wassim Daoud Khatoun James Brady Zhenjie Jin Paulo Da Silva Cordeiro Brad Fortunato David Peng Christopher Vellano Tim Heffernan Antoine Hollebecque Antoine Italiano Brandon M. Huffman James M. Cleary Jacob E. Berchuck Toni K. Choueiri Kimberly Perez Jonathan Nowak Andrew J. Aguirre Brian M. Wolpin Sylvan C Baca Matthew L. Freedman Harshabad Singh, 
    CANCER   

Mca14-006

Clinical and pathological characteristics of thin cutaneous melanomas with rapid recurrence.

Quote: Conclusions: Rapid recurrence of TM is associated with age 65 years, LM subtype, head/neck primary site, mitoses 1/mm2 and ulceration.
Abstract: https://www.medrxiv.org/content/10.64898/2026.04.04.26350182v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.04.04.26350182v1.full-text
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Search Authors: Prachi Bhave Terence Wong Kim Margolin Lotte Hoeijmakers Johanna Mangana Maria Grazia Vitale Paolo A Ascierto Andrea Maurichi Mario Santinami Georgina Heddle Clara Allayous Celeste Lebbe Adnan Kattak Stephan Forchhammer Jolien I Kessels Peter Lau Serigne N Lo Anthony A Papenfuss Grant A McArthur, 
    BRAIN    CANCER   

Mca14-008

PINK1 Expression as a Prognostic Biomarker in Glioblastoma Multiforme: An Observational Multicenter Study

Abstract: https://www.medrxiv.org/content/10.64898/2026.04.03.26350127v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.04.03.26350127v1.full-text
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Search Authors: Luis Alejandro Garcia Rairan span classnlm-suffixSr. valentina Corpus Gutierrez span classnlm-suffixJr. maria alexandra Del castillo span classnlm-suffixJr. Willian Riveros Castillo Javier Saavedra Gerena Andres David Turizo Smith Jaime Arias Guatibonza, 
    CANCER   

Mca14-010

Accelerometer-derived circadian rhythm and colorectal cancer risk in UK Biobank: a prospective cohort study

Abstract: https://www.medrxiv.org/content/10.64898/2026.04.03.26350124v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.04.03.26350124v1.full-text
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Search Authors: Maung Ni Chan Chin Javier Alejandro Berrio, 
    CANCER    HEART    LUNGS    RADIATION   

Mca14-012

Changes in Cardiorespiratory Fitness in Patients with Human Papillomavirus (HPV)-Related Oropharyngeal Cancer Undergoing Chemoradiotherapy

Abstract: https://www.medrxiv.org/content/10.64898/2026.04.03.26350101v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.04.03.26350101v1.full-text
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Search Authors: Michael Burgess Jack Thomson Ben Fox Emili Salaz Diaz Guy S Taylor Callum G Brownstein Muhammad Shahid Iqbal James OHara Rhona Sinclair Samuel T Orange, 
    CANCER   

Mca14-014

From Registration to Insight: How STRONG AYA Transforms Registry Data to Enhance Decision-Support Tools for Adolescent and Young Adult Oncology

Quote: Background Population-based cancer registers (PBCR) are important for monitoring trends in cancer epidemiology, facilitating the implementation of effective cancer services. Adolescents and Young Adult (AYA) with cancer are a patient group with a unique set of needs. The utility of PBCR in AYA is limited by the lack of AYA-specific data items. STRONG AYA, an international multidisciplinary consortium is addressing this through federated learning (FL) methodology and novel data visualisation concepts. A Core Outcome Set (COS) has been developed to measure outcomes of importance through clinical data and Patient Reported Outcomes (PROs).
Abstract: https://www.medrxiv.org/content/10.64898/2026.04.03.26350064v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.04.03.26350064v1.full-text
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Search Authors: Nicola Hughes Joshi Hogenboom Rob Carter Lee Norman Varsha Gouthamchand Oana Lindner Emily Connearn Aiara Lobo Gomes Anna Sikora-Koperska Magdalena Rosinska Katarzyna Pogoda Pawel Wiechno Paulina Jagodzinska-Mucha Iwona Lugowska Simone Hanebaum Andre Dekker Winette van der Graaf Olga Husson Leonard Wee Richard Feltbower Daniel Stark, 
    CANCER   

Mca14-016

Highresolution advanced diffusion MRI of rectal cancer surgical specimens: correlating microstructural characteristics with histology

Quote: Conclusion Diffusion MRI metrics quantitatively discriminated rectal wall tissue components ex vivo with histological validation, beyond T2-weighted contrast. DTI and DKI metrics characterized tumour, fibrous tissue, and muscularis propria invasion, supporting their potential as microstructural imaging biomarkers for treatment response assessment.
Abstract: https://www.medrxiv.org/content/10.64898/2026.04.02.26350055v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.04.02.26350055v1.full-text
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Search Authors: Ana R Fouto Hasti Cal Shermann Moreira Noam Shemesh Laura Fernandez Nuno Couto Ignacio Herrando Stephanie Nougaret Raluca Popita Jorge Brito Susana Our Miguel Chambel Nikolaos Papanikolaou Amjad Parvaiz Richard J. Heald Mireia Castillo-Martin Ins Santiago Andrada Ianus, 
    PRIME    CANCER    GENETICS   

Mga14-002

MyGeneRisk Colon: A Web-Based Tool for Personalized Colorectal Cancer Risk Prediction Based on Genetics and Lifestyle

Quote: To bridge this gap, we developed MyGeneRisk Colon, a publicly accessible web portal that delivers individualized CRC risk prediction by incorporating genetic, demographic, family history, and lifestyle factors. This paper details the development of the underlying risk prediction model, the portals architecture and data security, our reporting framework, and engagement with a community advisory panel. Designed as a user-friendly platform, MyGeneRisk Colon aims to effectively communicate personalized CRC risk profiles and educate users and healthcare providers about prevention strategies.
Abstract: https://www.medrxiv.org/content/10.64898/2026.04.03.26349669v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.04.03.26349669v1.full-text
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Search Authors: Jiayin Zheng Robert S Steinfelder Hang Yin Conghui Qu Minta Thomas Sushma S Thomas Cynthia Andrews Bianca Augusto Douglas C Corley Jeffrey K Lee Sonja I Berndt Andrew T Chan Stephen J Chanock Chris Gignoux Shauna R Goldberg Christopher A Haiman Jeroen R Huyghe Motoki Iwasaki Loic Le Marchand Soo Chin Lee Johana Melendez Ivan Mesa Shuji Ogino Viviam Sifontes Caroline Y Um Kala Visvanathan Larissa L White Andrea Williams Waverly Willis Alicja Wolk Taiki Yamaji Susan T Vadaparampil Gail P Jarvik Andrea N Burnett-Hartman Roger L Milne Elizabeth A Platz Jane C Figueiredo Wei Zheng Robert J MacInnis Julie R Palmer Stephanie L Schmit Iris Landorp-Vogelaar Ulrike Peters Li Hsu, 
    CANCER    GENETICS   

Mge14-008

Mutation-specific impairment of TET2 and DNMT3A enzymatic activity predicts clonal hematopoiesis disease risk

Quote: Clonal hematopoiesis of indeterminate potential (CHIP) driven by somatic mutations in TET2 and DNMT3A is present in 10 of adults over 60 and confers substantial risk for hematologic malignancy and cardiovascular disease, yet the majority of patients with CHIP do not progress to disease....

Integrating the activity score with the clinical models substantially improves prediction of incident cytopenia, myeloid neoplasm, and major adverse cardiovascular events.

Abstract: https://www.medrxiv.org/content/10.64898/2026.04.03.26350108v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.04.03.26350108v1.full-text
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Search Authors: Yash Pershad Kun Zhao Joseph C Van Amburg Robert W Corty Alyssa C Parker Alexander James Silver Yara F Almadani Ashwin Kishtagari Emily Hodges Michael R Savona J. Brett Heimlich Alexander G Bick, 
    CANCER    GENETICS   

Mge14-020

Genomic ascertainment of PALB2-related cancer predisposition

Quote: CONCLUSION Genomic ascertainment of PALB2-heterozygotes identifies elevated risk for multiple cancers and increased mortality, although risks were lower than estimates from familial ascertainment. These findings inform risk management for individuals identified through genomic screening.
Abstract: https://www.medrxiv.org/content/10.64898/2026.04.03.26349984v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.04.03.26349984v1.full-text
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Search Authors: Douglas Stewart Jung Kim Jeremy S Haley Jiang Li Michael R Sargen Hyokyoung G. Hong Marc Tischkowitz LIsa J. McReynolds David J. Carey, 

  Javilk's Research Links for Week 14
Updated 04/11/2026-01:28:16 AM
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