HEART
Mcr21-024	Is Left Atrial Appendage Closure a Universal Alternative to NOACs? A Meta-Analysis of NOAC-Era Trials
	Quote:	Conclusions LAAC significantly reduces non-procedural bleeding in moderate-risk AF patients, though this benefit attenuates in very high-risk populations. A consistent, statistically nonsignificant ischemic stroke trend and population-dependent efficacy establish LAAC as a shared decision-making alternative to NOACs rather than a universal replacement, pending 5-year CHAMPION-AF data.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.05.24.26353968v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.05.24.26353968v1.full-text
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	Search Authors:	Muhammad Awais Bodla Muhammad Aizaz Mustehsan Muhammad Munhib Shehzad Saira Afzal,
	See Also:	https://en.wikipedia.org/wiki/Left_atrial_appendage_occlusion
HEART
Mcr21-026	Multimodal atlas of human atherosclerosis links granular vascular cell states to coronary artery disease risk
	Quote:	We highlight candidate cell-specific regulatory mechanisms at less characterized CAD loci, including FGD5 and MCF2L in ECs. Together, this atlas represents an important step towards fully interpreting genetic risk loci and informing new therapeutic strategies for cardiovascular disease.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.05.24.26353986v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.05.24.26353986v1.full-text
	Search Similar:	Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho
	Search Authors:	Jose Verdezoto Mosquera Ivory Tang Maria Murach Gaelle Auguste Aditi Kodali Patrick Hart Douglas M. Shaw Minghong Li Adam W. Turner Chani J. Hodonsky Natalia M. Dworak Ana Karina de Oliveira Katia Sol-Church Teresa Jhee Kirsten I.M. van der Sijs Shaunak S. Adkar Ryan B. Choi Francesca Vacante Joseph C. Wu Paul Cheng Chiara Giannarelli Nicholas J. Leeper Aloke V. Finn Johan L.M. Bjorkegren Jason C. Kovacic Arif Yurdagul span classnlm-suffixJr. Sander W. van der Laan Clint L. Miller,
PRIME DIABETES EYES HEART
Sda211-004	Wegovy Linked to Rare Eye Stroke That Can Cause Sudden Blindness
	Quote:	A new analysis is raising concerns about Wegovy, the blockbuster weight-loss drug, after researchers found it may carry the highest risk of a rare eye stroke that can cause sudden vision loss.
	Article:	https://www.sciencedaily.com/releases/2026/05/260522023134.htm
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PRIME COGNITION HEART
Sda211-124	Common Heart Drug Taken by Millions Found Useless And Possibly Dangerous
	Quote:	A massive international study could upend 40 years of heart attack treatment. Researchers found that beta blockers routinely prescribed after uncomplicated heart attacks offered no real benefit
	Comment:	They rendered people forgetful and stupid, robbing them of their careers and humanity. My father used them. I had some prescribed for other metabolic reasons, but aside from the one dose I tried rendering me confident and stupid for several hours, making it impossible to imagine anything in the good science fiction I like to read, they had no effect.
	Article:	https://www.sciencedaily.com/releases/2026/05/260524021151.htm
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HEART MICROBIOME NUTRITION
Sda211-128	Beet Juice Lowers Blood Pressure in Older Adults in Just 2 Weeks
	Quote:	Drinking nitrate-rich beetroot juice may do more than support heart health it could actually reshape the bacteria living in the mouth in ways that help lower blood pressure in older adults.
	Article:	https://www.sciencedaily.com/releases/2026/05/260524021154.htm
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HEART
Sda211-130	Scientists Discover Hidden Liver Switch That Cuts Harmful Cholesterol
	Quote:	Scientists at UT Southwestern have uncovered a surprising new master switch that helps control how much cholesterol the liver sends into the bloodstream. The newly identified protein, HELZ2, works by shutting down the genetic instruction
	Comment:	Yet some of the longest living Italians have very high blood cholesterol.
	Article:	https://www.sciencedaily.com/releases/2026/05/260523103947.htm
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PRIME HEART NUTRITION
Sda213-038	Eating More Beans and Soy Could Slash High Blood Pressure Risk by Nearly 30%
	Quote:	Researchers found that people who regularly consumed foods such as beans, lentils, chickpeas, tofu, edamame, and soy milk were less likely to develop hypertension. The strongest benefits appeared at around 170 grams of legumes per day and 60 to 80 grams of soy foods daily. Legumes include foods like peas, lentils, chickpeas, and beans. Soy foods include tofu, soy milk, edamame, tempeh, and miso. Major Review Combined Data From Multiple Countries... Legumes and soy foods are rich in potassium, magnesium, and dietary fiber, nutrients already known to support healthy blood pressure.
	Comment:	Hmm../ There may alwo be some cultural contributions to lower blood pressure. I think that we Western Civilization types do tend to work and play harder, in part because we have more food and food security than some other cultures.
	Article:	https://nutrition.bmj.com/content/early/2026/05/04/bmjnph-2025-001449 https://www.sciencedaily.com/releases/2026/05/260523103906.htm
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Javilk's Research Links for Week 21
Updated 05/30/2026-01:22:31 AM
What interests you? What have you found? Tell me!
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Mcr21-024

Is Left Atrial Appendage Closure a Universal Alternative to NOACs? A Meta-Analysis of NOAC-Era Trials

Mcr21-026

Multimodal atlas of human atherosclerosis links granular vascular cell states to coronary artery disease risk

Sda211-004

Wegovy Linked to Rare Eye Stroke That Can Cause Sudden Blindness

Sda211-124

Common Heart Drug Taken by Millions Found Useless And Possibly Dangerous

Sda211-128

Beet Juice Lowers Blood Pressure in Older Adults in Just 2 Weeks

Sda211-130

Scientists Discover Hidden Liver Switch That Cuts Harmful Cholesterol

Sda213-038

Eating More Beans and Soy Could Slash High Blood Pressure Risk by Nearly 30%