| Research Topics: |
| INDEX |
| AI-chat 1 |
| PRIME 37 |
| aging 12 |
| body 2 |
| brain 17 |
| brainwave 3 |
| cancer 7 |
| climate 3 |
| cognition 10 |
| covid-19 6 |
| crime 3 |
| culture 3 |
| diabetes 6 |
| diagnostics 2 |
| disease 3 |
| drugs 1 |
| energy 1 |
| exercise 3 |
| eyes 1 |
| genetics 12 |
| gut 3 |
| heart 15 |
| immune 8 |
| kidneys 5 |
| language 2 |
| metabolism 2 |
| microbiome 2 |
| nutrition 11 |
| obesity 2 |
| physical 2 |
| politics 2 |
| pollution 2 |
| population 2 |
| practice 2 |
| privacy 2 |
| psychology 14 |
| quantum 1 |
| reproduction 2 |
| rights 1 |
| sleep 2 |
| space 1 |
| tech 2 |
| unk |
| vaccine 2 |
| virus 2 |
| war-confl |
| war-cyber 1 |
|
Scanned: 3012 Evaluated: 322 Selected: 92 |
| PRIME BODY COGNITION NUTRITION PHYSICAL | |||||||||||||||||||
Aef32-1013 | Schioliosis, the Serotonin Connection | ||||||||||||||||||
| Quote: | Abstract Recent research has suggested a potential association between serotonin and idiopathic scoliosis, a complex spinal deformity of unknown origin. Studies have explored genetic associations, altered serotonin levels, and the effects of serotonin-related medications in the context of idiopathic scoliosis. Genetic studies have identified significant associations between idiopathic scoliosis and serotonin-related genes, indicating a potential genetic predisposition to the condition. Furthermore, altered serotonin levels have been observed in patients with idiopathic scoliosis, with lower serum serotonin levels reported compared to healthy controls. This chapter reviews some of the published genomic variants associated with idiopathic scoliosis. The effects of serotonin-related medications have also been investigated, highlighting potential therapeutic benefits. However, the exact mechanisms underlying the association between serotonin and idiopathic scoliosis remain unclear, warranting further research. While theoretical and animal models have shown connections between serotonin metabolism and idiopathic scoliosis, there are uncertainties when translating this information into clinical practice for primary care and other musculoskeletal specialty providers. This chapter outlines the serotonergic pathways of musculoskeletal function, serotonin clinical laboratory testing methods, as well as clinical management strategies including pharmacological, nutrient, dietary, and lifestyle-based options. Keywords genomicsposturescoliosisserotoninspine Author Information Show 1. Introduction Serotonin, also known as 5-hydroxytryptamine (5-HT), is a neurotransmitter that plays a crucial role in the central nervous system (CNS). It is derived from the amino acid tryptophan and is involved in numerous physiological functions, including mood regulation, sleep, appetite, and cognition. Structurally, serotonin is a monoamine neurotransmitter with a chemical formula of C10H12N2O. It contains an indole ring and an amine group, making it a member of the indoleamine class of neurotransmitters. Serotonin exerts its effects by binding to specific receptors, mainly the 5-HT receptors, which are widely distributed throughout the brain and other tissues. While serotonins involvement in mental health disorders like depression and anxiety is well-established, recent research has also highlighted its potential role in the pathogenesis of idiopathic scoliosis, a complex spinal deformity of unknown origin. | ||||||||||||||||||
| Article: | https://www.intechopen.com/chapters/1157328 | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| AGING COGNITION LANGUAGE PSYCHOLOGY | |||||||||||||||||||
Mne32-005 | Multimodal Speech Composites Separate Age-Related, Subjective, and Clinical Cognitive Change in Narrative Recall Tasks | ||||||||||||||||||
| Quote: | Theory-driven multimodal composites reveal qualitatively distinct cognitive signatures across the aging-to-impairment continuum from a single brief task, with embedding-based features capturing variation invisible to standard scoring. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359965v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359965v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Michael J Kleiman Mirza Baig Natasha Clarke Andres Salcedo James E Galvin, | ||||||||||||||||||
| AGING COGNITION | |||||||||||||||||||
Mne32-007 | A Biologically Constrained Continuous-Time Framework for Long-Horizon Cognition Forecasting in Alzheimers Disease | ||||||||||||||||||
| Quote: |
The model also supports prognostic enrichment for Alzheimers clinical
trials, achieving up to 2.70x enrichment over the cohort base rate.
These results demonstrate that embedding biological disease mechanisms
within continuous-time deep learning improves the accuracy, biological
plausibility, and clinical utility of long-horizon cognitive
forecasting. The code is publicly available at: https:
github.com/PonDeepika/BEACON. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359964v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359964v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Pon Deepika Suresh Sunkari Sai Koundinya Upadhyayula span classnlm-collab data-hwp-idcollab-1The Alzheimers Disease Neuroimaging Initiative Vaanathi Sundaresan, | ||||||||||||||||||
| PRIME AGING COGNITION | |||||||||||||||||||
Mne32-011 | Plasma p-tau217 and NfL predict incident dementia in the community | ||||||||||||||||||
| Quote: | The association of p-tau217 with incident dementia differed by sex. DISCUSSION: These findings support the use of blood-based biomarkers for population-level dementia risk stratification, underscore the value of combining markers to improve prognostic precision, and can aid clinicians using plasma p-tau217 or NfL in interpreting dementia risk. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359934v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.07.26359934v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Anita Lenora Sunde Diego A Tovar-Rios Audun Osland Vik-Mo Henrik Zetterberg Burak Arslan Kubra Tan Hanna Huber Karin Persson Guglielmo Di Molfetta Ilaria Pola Marit Naess Haavard K Skjellegrind Geir Selbaek Nicholas J Ashton Dag Aarsland, | ||||||||||||||||||
| COGNITION PSYCHOLOGY | |||||||||||||||||||
Mpy32-009 | Genetic architecture of treatment-resistant schizophrenia across East Asian and European cohorts: insights from GWAS, TWAS, and synaptic pathway analyses | ||||||||||||||||||
| Quote: |
Although such treatment-resistant schizophrenia (TRS) shares a
substantial genetic liability with treatment-responsive schizophrenia,
the limited efficacy of dopamine antagonists in TRS indicates that
mechanisms beyond dopamine signalling likely contribute to
treatment-resistance, requiring the identification of alternative
biological pathways....
Our work suggests there is promise in pathway-level and multi-omics approaches to elucidate biologically meaningful heterogeneity within SSD and provides support for synaptic mechanisms as potential targets for understanding and stratifying treatment-resistance. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.06.26359853v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.06.26359853v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Perry BM Leung Kenneth CY Wong Sophie Smart Nick R Zhang Zoe ZY Zheng Jinghong Qiu Edoardo Spinazola Antonio Pardias Justin D. Tubbs Amy CY Liu Karen KY Ho Koi-Man Cheng Karen SY Hung Eric FC Cheung Vicki HM Ling Tomy CK Hui Ole A Andreassen Thomas R.E. Barnes Philippe Conus Benedicto Crespo Facorro Gillian A Doody Kim Q. Do Chin B Eap Eileen Joyce Ingrid Melle Paulo Menez Craig Morgan Francis A ONeill Baptiste Pignon Filip paniel Ilaria Tarricone Andrea Tortelli Alp ok Homero Vallada Javier Vzquez-Bourgon span classnlm-collab data-hwp-idcollab-1The STRATA Consortium Luis Alameda Evangelos Vassos James T.R. Walters James MacCabe Marta Di Forti Robin M Murray Hon-Cheong So Pak C Sham Simon SY Lui, | ||||||||||||||||||
| PRIME BRAIN COGNITION PSYCHOLOGY | |||||||||||||||||||
Mpy32-013 | Oxytocin reshapes fear control: intensity-dependent prefrontal dominance and whole-brain integration during naturalistic viewing | ||||||||||||||||||
| Quote: | At the large-scale network level, OT increased communication between frontoparietal/default-mode control networks and subcortical/limbic networks during high fear indicating more integrative fear regulation. A whole-brain fear neuromarker (CAFE) further confirmed intensity-dependent OT effects. Together, these findings indicate that OT modulates post-exposure fear experience and fear-related neural dynamics in ecologically valid contexts. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.11.26360155v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.11.26360155v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Kun Fu Shuyue Xu Dan Liu Zheng Zhang Qi Liu Jingxian He Ting Xu Can Liu Junjie Wang Yuan Zhang Feng Zhou Xiaodong Zhang Chunmei Lan Mengfan Han Menghan Li Zhen Liang Bharat Biswal Keith M Kendrick Weihua Zhao Dezhong Yao Benjamin Becker, | ||||||||||||||||||
| Search Words: |
| ||||||||||||||||||
| COGNITION LANGUAGE PSYCHOLOGY | |||||||||||||||||||
Mpy32-015 | A double index for assessing symptoms in psychosis based on acoustic and semantic information | ||||||||||||||||||
| Quote: | Recent computational approaches to speech in psychosis generate large multidimensional feature spaces capturing semantic and acoustic aspects of language production. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.11.26360092v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.11.26360092v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Maryia Kirdun Rui He Cemal Demirlek Jose Tomas Garcia-Molina Roya Huppi Werner Surbeck Noemi Dannecker Burcu Verim Berna Yalincetin Victor Ortiz Garcia de la Foz Rosa Ayesa Arriola Emre Bora Alicia I. Figueroa-Barra Filip Spaniel Lena Palaniyappan Iris E. Sommer Philipp Homan Wolfram Hinzen Claudio Palominos, | ||||||||||||||||||
| COGNITION PSYCHOLOGY | |||||||||||||||||||
Mpy32-016 | miR-151a-5p in Neuron-Derived Extracellular Vesicles Mediates Antidepressant Response | ||||||||||||||||||
| Quote: | Moreover, administration of miR-151a-5ploaded NEVs in a model of depressive-like behavior produced rapid antidepressant-like effects. Together, these findings identify a vesicle-based mechanism linking peripheral biomarkers to central pathophysiology and demonstrate that miR-151a-5p functions both as a predictor and effector of antidepressant response. | ||||||||||||||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.08.11.26360193v1 | ||||||||||||||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.08.11.26360193v1.full-text | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
| Search Authors: | Dariusz Zurawek Alice Morgunova Laura M Fiori Jennie Yang Reine Khoury Claudia Belliveau Maria-Antonietta Davoli Pascal Ibrahim Anjali Chawla Sierra Codeluppi Faranak Farzan Sidney H Kennedy Raymond W Lam Roumen Milev Daniel Mueller Claudio Soares Susan Rotzinger Valeria Taylor Rudolf Uher Jane Foster Benicio N Frey Naguib Mechawar Cecilia Flores Corina Nagy Gustavo Turecki, | ||||||||||||||||||
| BRAIN COGNITION | |||||||||||||||||||
Sd321-037 | Scientists Say Just 7 Days of Meditation Can Rewire Your Brain | ||||||||||||||||||
| Quote: | "Weve known for years that practices like meditation can influence health, but whats striking is that combining multiple mind-body practices into a single retreat produced changes across so many biological systems that we could measure directly in the brain and blood," said senior study author Hemal H. Patel, Ph.D., professor of anesthesiology at UC San Diego School of Medicine and research career scientist at the Veterans Affairs San Diego Healthcare System. "This isnt about just stress relief or relaxation; this is about fundamentally changing how the brain engages with reality and quantifying these changes biologically." | ||||||||||||||||||
| Comment: | Those who relax and reflect live far easier lives than those who only react to the immediate. The brain just works better when relaxed and not hepped up on alcohol or coffee. | ||||||||||||||||||
| Article: | https://www.sciencedaily.com//releases/2026/08/260807235243.htm | ||||||||||||||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | ||||||||||||||||||
|
Javilk's Research Links Newsletter for Week 32 Updated 08/15/2026-01:24:35 AM What interests you? What have you found? Tell me! Drop me a note to subscribe or submit something. |