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    PRIME    DISEASE    POPULATION    PRACTICE   

Mep32-015

A clinical care intensity atlas of 505 diseases from 90 million people

Quote: To our knowledge, this is the first whole-phenome care-intensity atlas built by one uniform rule. Because the score counts only delivered care, it under-captures a burden that is experienced but never coded, most severely in mental illness. We release the complete atlas with this paper, all 505 disease scores with confidence intervals, and the external crosswalks that anchor them.
Comment: Interesting charts. Care intensity varies across the USA, lowin the northern Midwest, high along the East Coast.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.10.26360114v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.10.26360114v1.full-text
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Search Authors: Benjamin Kramer Andrey Rzhetsky, 
    GENETICS    POPULATION    REPRODUCTION   

Mep32-021

Population Differences in the Epidemiology, Phenotype, and Genetics of Hirschsprung Disease in the United States

Quote: Genetically, the major difference in Blacks is the unique association with noncoding regulatory variation at the SOX10 gene not observed in Whites. Meaning These findings uncover significant population differences in incidence and clinical presentation, but limited qualitative but greater quantitative genetic differences, in Hirschsprung disease. Beyond being useful for understanding HSCR natural history and for genetic counseling, it begs for research on the causes of the variable frequency and presentations across populations.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.10.26360052v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.10.26360052v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Mingzhou Fu Hanna E Berk-Rauch Monica Erazo Sumantra Chatterjee Aravinda Chakravarti, 
Search Words:
Hirschsprung Disease neonatal intestinal blockage Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 

  Javilk's Research Links Newsletter for Week 32
Updated 08/15/2026-01:24:35 AM
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