Research
Topics:
INDEX
MCS 2
PRIME 22
aging 14
body 1
brain 11
brainwave 1
cancer 6
climate 3
cognition 4
computers 1
crime 1
dental 1
diabetes 3
drugs 5
economy 1
energy 1
exercise 1
eyes 1
genetics 4
gut 2
heart 4
herbs 1
immune 4
language 1
metabolism 2
microbiome 2
nutrition 14
obesity 1
pain 1
politics 2
psychology 5
quantum 1
reproduction 1
sleep 2
tech 1
unk
vaccine 2
virus 1
war-confl
 
Scanned: 2763
Evaluated: 216
Selected: 48
 
    AGING    BRAIN   

Bgn34-009

Cell type-resolved chromatin accessibility clocks for brain aging

Article: https://www.biorxiv.org/content/10.64898/2026.08.22.746439v1
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Search Authors: Patrick Yu Doudou Yu Yao Xue William Stafford Noble, 
    AGING    COGNITION    DIABETES   

Mdb34-002

Glucagon-like peptide-1 receptor agonist initiation and risk of clinically recorded Alzheimers disease-type dementia in older adults with type 2 diabetes: a target trial emulation using causal machine learning

Quote: Interpretation GLP-1 receptor agonists may delay clinically recorded AD-type dementia compared with SU. Comparative effectiveness versus SGLT2 inhibitors may vary, supporting further study. Given the hypothesis-generating nature of these findings, diabetes treatment selection should remain guided by glycemic, cardiovascular, renal, and patient-centered considerations.
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.21.26361012v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.21.26361012v1.full-text
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Search Authors: Jonas Schroeder Octavia-Andreea Ciora Philip Heesen Martin Bendszus Johannes Levin Robert Perneczky Lia Bally Stefan Feuerriegel, 
    AGING    COGNITION   

Mne34-007

Domain-Specific Effects of GABA-Modulating Pharmacotherapies in Autism Spectrum Disorder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Abstract: https://www.medrxiv.org/content/10.64898/2026.08.23.26361086v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.23.26361086v1.full-text
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Search Authors: Sanjana Palakodeti Kirti Kumar Hinduja Garima Misra Subhiksha R Abhigna Pabbaraju Bagath Srinivasan Balaji Tejesvi Parmar, 
    AGING    BRAIN    BRAINWAVE   

Mne34-010

Transcranial alternating current stimulation for Parkinsons disease: a systematic review and meta-analysis of motor outcomes

Quote: The prediction intervals indicated substantial uncertainty, and significant between-study heterogeneity was observed, particularly for tremor outcomes (I2 86.1). This variability and limitation in evidence quality is largely driven by small sample sizes, highly heterogeneous stimulation protocols, and varying outcome assessments. Systematically, tACS was generally well-tolerated, with no serious adverse events reported across the included studies; however, formal safety assessment was beyond the scope of this review. Current exploratory evidence shows a lack of consistent improvements in motor symptoms or functions in PD largely due to protocol-level heterogeneity.
Comment: It appears t ome that medicine is still learning what to do, and most researchers are more interested in disproving or writing papers than really exploring the variations in frequencies and intensities to determine what works for which type of person and Parkinsons variant..
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.21.26360996v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.21.26360996v1.full-text
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Search Authors: Thuy Tien Mai Tea Gjishti Karsten Witt Mandy Roheger Christoph S. Herrmann, 
    PRIME    AGING    IMMUNE   

Sd341-001

People Who Live Past 110 Have an Unusual Abundance of Killer Immune Cells

Quote: These cells have previously been shown to kill tumor cells in certain cancers. During illness, they can also reproduce rapidly through a process called clonal expansion, helping the immune system respond to infection. New research published August 19 in the Cell Press journal Cell Reports suggests that this same type of immune activity may be associated with healthy aging in people who live beyond 110.
Article: https://www.sciencedaily.com//releases/2026/08/260823014950.htm
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    PRIME    AGING    SLEEP   

Sd341-007

Too Much or Too Little Sleep May Make Your Body Age Faster

Quote: Both too little and too much sleep may be linked to faster aging throughout the body. Researchers analyzing 23 biological aging clocks found the lowest aging levels among people sleeping about 6.4 to 7.8 hours per day.
Article: https://www.sciencedaily.com//releases/2026/08/260823094156.htm
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    AGING    BRAIN    GENETICS   

Sd341-013

A Major Alzheimers Risk Gene May Shrink Brain Cells Years Before Symptoms

Quote: Researchers have uncovered a possible reason why the Alzheimers risk gene APOE4 can disrupt the brain long before memory problems begin. In mice, APOE4 increased a protein called Nell2, shrinking neurons and making memory circuits unusually active. That early hyperactivity predicted worse memory later in life. Reducing Nell2 in adult mice reversed the abnormal changes, raising hopes for a new way to intervene before Alzheimers progresses.
Article: https://www.sciencedaily.com//releases/2026/08/260821012234.htm
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    PRIME    AGING    COGNITION    NUTRITION   

Sd341-016

This Common Vitamin Was Linked to 13 Better Cognitive Scores

Quote: Older adults with mild cognitive impairment and sleep problems who took at least 5,000 IU of vitamin D daily scored more than 13 higher on a cognitive test than those taking none. The preliminary findings suggest vitamin D could be worth studying
Article: https://www.sciencedaily.com//releases/2026/08/260822015138.htm
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    PRIME    AGING    BRAIN    LANGUAGE   

Sd341-025

Multilingual People May Have Brains Up to 13 Years Younger

Quote: People who speak several languages may have brains that age more slowly, with four-language speakers showing brains that appeared about 13 years younger than those of monolinguals.
Article: https://www.sciencedaily.com//releases/2026/08/260821012226.htm
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    PRIME    AGING    BRAIN    DRUGS   

Sd341-039

Cannabis Use Linked to 37 Higher Stroke Risk in Massive Study

Quote: Researchers at the University of Cambridge have found that cannabis, cocaine, and amphetamines are associated with a significantly greater risk of stroke, including among younger people. The findings come from an analysis that drew on data involving more than 100 million people.
Article: https://www.sciencedaily.com//releases/2026/08/260822015215.htm
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    PRIME    AGING    IMMUNE    NUTRITION   

Sd343-002

Scientists May Have Found a Shortcut to Calorie Restrictions Anti-aging Benefits

Quote: A new study, published in Nature Aging, points to a possible answer involving an immune protein called complement component 3 (C3). Yale researchers have previously shown that people who followed moderate calorie restriction, cutting calorie intake by 14 for two years, developed stronger immune defenses without experiencing problems related to growth or reproduction.
Article: https://www.sciencedaily.com//releases/2026/08/260826055508.htm
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    AGING    NUTRITION   

Sd343-005

What You Eat Before Age 2 May Affect Your Health 70 Years Later

Quote: Britains postwar sugar rationing created a rare natural experiment that let researchers examine how early sugar exposure might affect health decades later. People who experienced more rationing during their first 1,000 days had lower rates of several cancers and showed signs of slower biological aging. They were also still eating less sugar and maintaining healthier diets around age 50.
Article: https://www.sciencedaily.com//releases/2026/08/260824065522.htm
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    PRIME    AGING    GENETICS    HEART    NUTRITION   

Sd343-011

Your Genes May Decide Whether a Low-carb Diet Sends Cholesterol Soaring

Quote: Low-carb diets have become increasingly popular, but their effects on cholesterol are far from uniform. Some people see little change, while others experience a substantial increase. New research suggests that genetics may help explain why. The findings indicate that saturated fat, which can make up a larger share of some low-carb diets, may interact with a persons genetic makeup to raise low-density lipoprotein (LDL) cholesterol, a major contributor to heart disease risk.
Article: https://www.sciencedaily.com//releases/2026/08/260823015009.htm
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    MCS    AGING    VACCINE   

Sd343-013

Shingles Vaccine Linked to 24ower Dementia Risk

Article: https://www.sciencedaily.com//releases/2026/08/260823015013.htm
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  Javilk's Research Links Newsletter for Week 34
Updated 08/29/2026-12:26:24 AM
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