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Mne34-010

Transcranial alternating current stimulation for Parkinsons disease: a systematic review and meta-analysis of motor outcomes

Quote: The prediction intervals indicated substantial uncertainty, and significant between-study heterogeneity was observed, particularly for tremor outcomes (I2 86.1). This variability and limitation in evidence quality is largely driven by small sample sizes, highly heterogeneous stimulation protocols, and varying outcome assessments. Systematically, tACS was generally well-tolerated, with no serious adverse events reported across the included studies; however, formal safety assessment was beyond the scope of this review. Current exploratory evidence shows a lack of consistent improvements in motor symptoms or functions in PD largely due to protocol-level heterogeneity.
Comment: It appears t ome that medicine is still learning what to do, and most researchers are more interested in disproving or writing papers than really exploring the variations in frequencies and intensities to determine what works for which type of person and Parkinsons variant..
Abstract: https://www.medrxiv.org/content/10.64898/2026.08.21.26360996v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.08.21.26360996v1.full-text
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Search Authors: Thuy Tien Mai Tea Gjishti Karsten Witt Mandy Roheger Christoph S. Herrmann, 

  Javilk's Research Links Newsletter for Week 34
Updated 08/29/2026-12:26:24 AM
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