Research
Topics:
INDEX
AI-chat 3
MCS 2
PRIME 26
aging 9
brain 5
cancer 11
catastrophy 1
censorship 1
climate 1
cognition 6
covid-19 1
culture 2
dental 1
diabetes 3
diagnostics 1
economy 3
energy 3
exercise 1
eyes 4
genetics 7
gut 1
heart 2
immune 5
language 3
law 1
lungs 1
metabolism 2
microbiome 2
misc 1
nutrition 4
pain 1
physical 1
politics 3
pollution 1
privacy 1
psychology 3
rights 1
space 1
vaccine 1
virus 1
 
Scanned: 2073
Evaluated: 266
Selected: 60
 
    PRIME   

Bbe36-009

Specificity-driven protein binder design with Odin-Multi

Article: https://www.biorxiv.org/content/10.64898/2026.09.08.749745v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Valentas Brasas Charlotte R. Christensen Kasper H. Bjrnsson Victor Emil Mller Beatrice Scapolo Melisa Benard-Valle Mads Mrup Nygaard Jens Christian Nielsen Sine Reker Hadrup Kristoffer H. Johansen Timothy P. Jenkins, 
    PRIME   

Bcb36-005

SUMOylation is a Therapeutic Vulnerability in High-risk Neuroblastoma

Article: https://www.biorxiv.org/content/10.64898/2026.09.05.749647v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Antti Kukkula Saiganesh Sriraman Verneri Virtanen Sara LM Kuusela Lara Kozina Bubnic Ilkka Paatero Daniel Bexell Maria Sundvall, 
    PRIME    CANCER   

Bcb36-006

Melittin-induced membrane disruption in hepatocellular carcinoma involves mtROS/GSDME-mediated pyroptosis

Quote: Collectively, our findings provide, to our knowledge, the first evidence that melittin induces pyroptotic cell death in HCC cells through a mechanism involving mitochondrial oxidative stress and GSDME processing. These results extend the conventional view of melittin as a direct membrane-lytic peptide and uncover an mtROS/GSDME-associated pyroptotic mechanism underlying its antitumour activity in HCC.
Article: https://www.biorxiv.org/content/10.64898/2026.09.05.749568v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: He Zang Meng Lu Nian Fan Yunzhen Yang Jianfeng Qiu Dafu Chen Rui Guo, 
    PRIME    AGING    CANCER   

Bcb36-010

Stochastic Boolean Model of Death Signaling in MCF7:5C Predicts Cell Death Inducers and Inhibitors

Quote: We identified 30 resistant cell strains with double mutations and 506 drug-target combinations capable of inducing four distinct modes of cell death: direct CASP7 activation, extrinsic apoptosis, intrinsic apoptosis, and combined intrinsic/extrinsic apoptosis. Overall, our model successfully explains the drug response behavior of MCF7:5C cells, predicts mechanisms of drug resistance, and suggests treatment strategies to overcome this resistance.
Article: https://www.biorxiv.org/content/10.64898/2026.09.05.749284v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Kittisak Taoma Teeraphan Laomettachit Surojeet Sengupta Yue Wang Robert Clarke Pavel Kraikivski, 
    PRIME    VACCINE    VIRUS   

Bim36-008

Smallpox Vaccine Elicits CD8 T Cell Immunity Persisting Over Four Decades with Cross-Recognition of Monkeypox Virus

Article: https://www.biorxiv.org/content/10.64898/2026.09.08.750003v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Yujuan Du zongmian yang Yinying Xiao Huajun Duan Kong Hong Jun Su Chanchan Xiao, 
    PRIME    COGNITION   

Bne36-002

What is common to memory retrieval and relational reasoning? Testing neural overlap in anterior lateral prefrontal cortex

Quote: Thus, we hypothesize that neural overlap in this area reflects engagement in relational thinking during memory retrieval monitoring. Together, these results move beyond general characterizations of aLPFC function by testing whether it meets a precondition -- individual-level neural overlap across varied tasks -- of a unified neurocognitive function in support of reasoning and memory retrieval.
Article: https://www.biorxiv.org/content/10.64898/2026.09.06.749563v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Allison Chen Margaret Vashel Mariam Aly Silvia Bunge, 
    PRIME    DIABETES    EYES   

Mdb36-002

Glucose Dispersion Is Associated With Contrast Sensitivity Beyond Average Glycemia

Quote: Conclusion: Glucose dispersion is associated with contrast sensitivity beyond average glycemia, suggesting that glycemic exposure may relate to visual function through its average level and dispersion.
Abstract: https://www.medrxiv.org/content/10.64898/2026.09.08.26362509v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.09.08.26362509v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Ren Zhang, 
    PRIME    EYES   

Mdb36-004

Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy: Notoriety Bias or True Ocular Toxicity?

Quote: Conclusions Pharmacovigilance and genetic evidence converge to show that the semaglutide-NAION signal reflects notoriety bias rather than toxicity.
Abstract: https://www.medrxiv.org/content/10.64898/2026.09.06.26362369v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.09.06.26362369v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Junhong Jiang Di Hu Xinsheng Li Qipeng Ling Qi Zhang Lili Dong Zenan Lin, 
    PRIME    MICROBIOME    NUTRITION   

Mnu36-003

Effects of Walnut Supplementation on Short-Chain Fatty Acid Levels in Healthy Volunteers

Quote: Walnut intake was associated with an overall 2.8 increase in alpha diversity, a 17.6 reduction in estimated marginal mean F/B ratio, and an overall reduction in three luminal proteolytic metabolites associated with gut dysbiosis: isobutyric acid, valeric acid, and isovaleric acid. Interestingly, the effects on the gut metabolome were more pronounced in obese individuals, with significant decreases observed in the same three SCFAs, as well as p-cresol. Given the known associations between these luminal proteolytic metabolites and gut dysbiosis, these results suggest that walnut intake may help to attenuate overall gut dysbiosis, particularly in obese populations.
Abstract: https://www.medrxiv.org/content/10.64898/2026.09.08.26362468v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.09.08.26362468v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Thomas Petrillo Raad Gharaibeh James J Grady Alexey Melnik Alexander A Aksenov John Birk Haleh Vaziri Huijia Liu Christian Jobin Daniel Rosenberg, 
    PRIME    NUTRITION    PHYSICAL   

Mnu36-004

Malnutrition Diagnosis: Validation of a Weight-Independent GLIM-Adapted Framework in U.S. Adults (NHANES 1999"2020)

Quote: Thus, low BMI exhibits low diagnostic sensitivity in modern U.S. cohorts. Excluding BMI successfully bypasses circularity, unmasks qualitative muscle wasting under excess body weight, and establishes a robust, weight-independent standard for clinical and epidemiological research.
Abstract: https://www.medrxiv.org/content/10.64898/2026.09.04.26362229v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.09.04.26362229v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: F. Orsini A. Novella L. Pasina, 
    MCS    PRIME    IMMUNE   

Mpa36-002

Dysregulation of microRNAs in fibromyalgia: potential as biomarkers and disorder modulators

Quote: This analysis revealed enrichment in pathways central to cell signaling and immune function, such as regulation of PTEN, circadian rhythm and RNA metabolic processes. Additionally, the dysregulated miRNAs in FMS were over-represented in immune-related tissues such as lymph node and spleen.
Abstract: https://www.medrxiv.org/content/10.64898/2026.09.08.26362323v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.09.08.26362323v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Alessandra Tamashiro-Orrego David Andersson Rocio T Martinez-Nunez, 
    PRIME    AGING    CATASTROPHY    PAIN    PSYCHOLOGY   

Mpa36-003

Childhood trauma, accelerated biological aging and chronic pain across two population cohorts

Quote: Epigenetic age acceleration (EAA), a DNA methylation marker of biological aging, may represent a pathway through which early-life stress becomes embedded....

Findings CT was associated with chronic pain and with accelerated biological aging measured primarily using second- and third-generation clocks. Associations were consistently stronger in women, and smoking-related methylation contributed substantially to the relationship between EAA and chronic pain. Mediation analyses revealed that EAA partially accounts for the link between CT and chronic pain in women.

Abstract: https://www.medrxiv.org/content/10.64898/2026.09.08.26362416v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.09.08.26362416v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Hannah Russell Sam Singleton Lesley Colvin Gary Macfarlane Steve Cole Christopher G Bell Tim G Hales, 
Search Words:
Epigenetic age acceleration (EAA) Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
childhood trauma (CT) Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    MCS    PRIME   

Mrh36-004

Prevalence of Small Fibre Pathology in Fibromyalgia: An Updated Systematic Review and Meta-Analysis Showing Increasing Heterogeneity

Comment: They say no, but some say yes. The references might be interesting.
Abstract: https://www.medrxiv.org/content/10.64898/2026.09.05.26362344v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.09.05.26362344v1.full-text
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Vincius Arantes Campos Allan Gomes Doriguetto, 
    PRIME    SPACE   

Sd363-010

Dark Energy Debunked? Cosmic Acceleration May Be an Illusion

Quote: "There is increasing evidence that the brightness of Type Ia supernovae depends on the age of the stars they come from," said Professor Subir Sarkar of Oxfords Rudolf Peierls Centre for Theoretical Physics, a co-author of the study. "If this effect is not accounted for, it can lead to the erroneous conclusion that the expansion rate is accelerating." A Universe That May Be Slowing Down. Once the researchers applied the stellar age correction, they found that the observations no longer favored a universe undergoing uniform acceleration. Their analysis instead indicates that, overall, cosmic expansion may be slowing rather than speeding up.
Comment: That makes more sense than those "mysterious dark forces" of the universe.
Article: https://www.sciencedaily.com//releases/2026/09/260907201600.htm
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    PRIME    AGING    BRAIN    NUTRITION   

Sd363-016

Popular Brain Supplement Linked to Shorter Lifespan in Men

Quote: Researchers led by Jie V. Zhao, Yitang Sun, Junmeng Zhang, and Kaixiong Ye from the University of Hong Kong and the University of Georgia examined whether phenylalanine and tyrosine, two amino acids involved in metabolism and brain function, are connected to lifespan (lifespan). Their results point to a notable difference between men and women. Higher tyrosine levels were associated with shorter life expectancy in men, while no significant effect was detected in women.
Article: https://www.sciencedaily.com//releases/2026/09/260904000330.htm
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    PRIME    CANCER   

Sd363-037

Scientists Find a New Weakness in Treatment-Resistant Prostate Cancer

Quote: Earlier research had linked the loss of two genes, TP53 and RB1, with transdifferentiation in prostate cancer. Exactly why losing those genes causes such a dramatic change in tumor cell identity, however, remained unclear. To investigate, the researchers examined several prostate cancer cell lines and studied which cellular pathways changed when TP53 and RB1 were missing. "We saw that there are two sides to this transition: loss of glandular genes and activation of cell programs that cause the identity to switch into stem cells," said Joshi Alumkal, M.D., Professor of Internal Medicine-Hematology/Oncology and member of Rogel Cancer Center.
Article: https://www.sciencedaily.com//releases/2026/09/260904000324.htm
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    PRIME    POLLUTION   

Sd363-039

Common Dry-Cleaning Chemical Linked to Triple the Risk of Liver Scarring

Quote: A chemical commonly used in dry cleaning and found in some household products may be an overlooked threat to liver health. Researchers found that people with detectable levels of tetrachloroethylene (PCE) in their blood were three times more likely to have significant liver fibrosis, a dangerous buildup of scar tissue that can eventually lead to liver failure or cancer. The risk climbed sharply as PCE levels increased, even after accounting for factors such as age, sex, race, education, alcohol use, and metabolic conditions.
Article: https://www.sciencedaily.com//releases/2026/09/260906170149.htm
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    PRIME    EYES   

Sd363-040

Cialis Linked to Higher Glaucoma Risk in Large Study

Quote: A large study of nearly 74,000 men suggests that long-term use of tadalafil, best known as Cialis, may be linked to a higher risk of glaucoma and other eye pressure problems. Men prescribed the drug for urinary symptoms caused by an enlarged prostate were 22 more likely to develop glaucoma, 32 more likely to develop ocular hypertension, and 33 more likely to be diagnosed with primary open-angle glaucoma or start glaucoma treatment over five years.
Article: https://www.sciencedaily.com//releases/2026/09/260906170134.htm
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    PRIME    CLIMATE    ECONOMY   

Zzf36-1004

Norway Rejects Climate Orthodoxys False Choice, Builds Wealth

Quote: Here is where the story stops being about the Arctic and becomes about everyone else. Norway is not a struggling petro-state rationalizing a bad habit. It is among the richest societies ever built, with per capita gross domestic product above 105,000 and a sovereign wealth fund that crossed 2.39 trillion in June. Five and a half million people have converted seabed hydrocarbons into universal healthcare, free universities, and pensions for grandchildren not yet born. If Norway considers oil and gas indispensable to its economic position, it is unreasonable to demand that poorer countries abandon their own resources. This matters enormously for Africa, South Asia, and other rapidly developing regions. For many African households, unreliable energy can be catastrophic.
Article: https://pjmedia.com/vijay-jayaraj/2026/09/04/norway-rejects-climate-orthodoxys-false-choice-builds-wealth-n4956903
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    PRIME    COGNITION    LANGUAGE   

Zzf36-1010

Average Length Of A Word: English And Global Comparisons

Comment: Language shapes throught. This site is about the Features and Structure of Languages, of which word length is but one aspect. A Fascinating site.
Article: https://codecraftwp.com/average-length-of-a-word/
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    PRIME    AGING    BRAIN    DIAGNOSTICS   

Zzf36-1016

Alzheimers Screening and Prevention (ASAP) Act.

Quote: Last year, the Food and Drug Administration (FDA) cleared two new blood-based diagnostic tests for Alzheimers. This is massive news for patients and their families looking for answers about their brain health in increasingly desperate fashion. These tests are a significant and necessary improvement over traditional alternatives such as positron emission tomography scans or CSF testing, a particularly cringeworthy procedure in which a specialist must perform a spinal tap. These new blood-based tests are both less expensive and far less invasive. Research is also underway to evaluate whether blood tests such as these could help detect Alzheimers well before patients begin to show symptoms....

Thankfully, a solution is on the table to help clear a path for patients to benefit from these advances: the Alzheimers Screening and Prevention (ASAP) Act. The ASAP Act would allow Medicare coverage of FDA-cleared blood tests for routine Alzheimers screening. Experts agree that expanding access to early screening must be the starting point for addressing this crisis.

Article: https://pjmedia.com/christian-josi/2026/09/09/pass-asap-asap-n4957037
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    AI-CHAT    PRIME    LANGUAGE   

Zzf36-1028

How Many Words in the English Language?

Quote: Search this question and you will be handed 171,476, then 470,000, then 600,000, then "over a million," often on the same page, each stated as fact. None of those figures is a mistake. They are answers to four different questions, and almost nobody says which question they answered.
Article: https://wordstatus.com/blog/how-many-words-are-in-the-english-language/
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
See Also:
  • https://codecraftwp.com/average-length-of-a-word/
    •     AI-CHAT    PRIME   

    Zzf36-1067

    Anthropics Self-Serving Doomsday Narrative

    Quote: There is nothing wrong with that, of course. Every company plays the angles. The problem is what happens when the people writing the rules get to decide what "safety" means, because we have seen this movie before. Remember the "trust and safety" teams at social media platforms? What about the UKs "Online Safety Act"? Lets not forget about COVID censorship justified, of course, in the name of "safety."
    Comment: "Ve ist so far ahead of everybody else is is scary" Propaganda? Hmmm...
    Article: https://www.breitbart.com/tech/2026/09/10/bokhari-anthropics-self-serving-doomsday-narrative/
    Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
        PRIME    PRIVACY    RIGHTS   

    Zzf36-1073

    Wisconsins Flock Fight Just Became a Fourth Amendment Case

    Quote: "If there just would have been some sort of oversight, like a warrant requirement from a judge, then these abuses would have been caught," he said. "Thats really the purpose of the Fourth Amendment, is to provide a check on law enforcement and to make sure that when theyre using very powerful surveillance tools, like Flock cameras, that those requests are reviewed before theyre put in the field," he added.
    Comment: 4th Ammendment: The right of the people to be secure in their persons, houses, papers, and effects,a against unreasonable searches and seizures, shall not be violated, and no Warrants shall issue, but upon probable cause, supported by Oath or affirmation, and particularly describing the place to be searched, and the persons or things to be seized.
    Article: https://pjmedia.com/david-manney/2026/09/10/wisconsins-flock-fight-just-became-a-fourth-amendment-case-n4957100
    Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
    See Also:
  • https://en.wikipedia.org/wiki/Fourth_Amendment_to_the_United_States_Constitution
    •     PRIME    ECONOMY    POLITICS   

    Zzf36-1079

    The 5K Check Heard Round the World: How Donald Trump Reverse Unod the Midterms

    Quote: Experts said that it would be difficult to mount a legal challenge on the premise that the payments constituted bribery, likening Mr. Trumps "dividend" to a pledge to deliver a tax break. "A promise to lower taxes also gives voters a financial reason to support a candidate, but that does not, by itself, make the promise a bribe," Mr. John Day said. "Under the proposal as announced, an eligible adult could vote Democratic or not vote at all and still receive the same payment if the program were enacted."
    Comment: It sure sounds like the usual election bribery of promises to lower your health care costs, give you tax breaks, and all the other stuff those poly tics say at election time. But it is true that if the new congress is full of democrats, they will kill his tariffs and other policies, so there will be no tariff dividend money to give us. As for me, Id prefer that money be used to pay off our national debt. But yes, this will stimulate the economy and thus improve all our lives one way of another.
    Article: https://pjmedia.com/scott-pinsker/2026/09/10/the-5k-check-heard-round-the-world-how-donald-trump-reverse-unod-the-midterms-n4957080
    Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
        PRIME    CENSORSHIP    CULTURE    LAW    POLITICS   

    Zzg36-1005

    This Was the Most Important Part of RFK Jr.s Convention Speech

    Quote: Kennedy brought up how Biden ordered Facebook and Instagram to delete his accounts just 37 hours into Bidens presidency, cutting off public debate before it could start. "Im not complaining about what happened to me," he said, "but it was a bad thing for our country." Democrats gutted the right of assembly by means of social-distancing orders, which Kennedy described as "completely unscience-based." They also undermined the Seventh Amendment right to a jury trial by providing pharmaceutical companies with liability shields, a protection so absolute that, in Kennedys words, "no matter how negligent they were, no matter how reckless, no matter how toxic the ingredients, no matter how grievous your injury, you could not sue them." Democrats violated the Fifth Amendment by shutting down three million businesses with no due process and no compensation, Kennedy said, and they trampled the Fourth Amendment by forcing Americans to disclose private medical information before they could exercise their constitutional rights. "In a single year, my party obliterated 250 years of constitutional guarantees," Kennedy said. "The only bill of rights that they left unscathed was the Second Amendment, and probably only because there is a Second Amendment."
    Article: https://pjmedia.com/matt-margolis/2026/09/11/this-was-the-most-important-part-of-rfk-jrs-convention-speech-n4957122
    Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 

      Javilk's Research Links Newsletter for Week 36
    Updated 09/15/2026-02:09:31 AM
    What interests you? What have you found? Tell me!
    Drop me a note at Javilk.com to subscribe or submit something.