PRIME DRUGS NUTRITION PSYCHOLOGY
Aee40-1024	Get Off Drugs -- a Pilot Study with a 100 Percent Success Rate with NO Withdrawal Symptoms
	Comment:	I gave related papers and a bottle of vitamin C to one drug addict I encountered at a metals recyclery. I saw him two weeks later. He thanked me for freeing him from addiction, saying there were no withdrawal symptoms as in his prior efforts to kick his drug habit.
	Article:	https://isom.ca/wp-content/uploads/2020/01/JOM_1977_06_4_02_The_Hypoascorbemia-Kwashiorkor_Approach_to_Drug_Addiction-.pdf
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	See Also:	http://mall-net.com/chathcart/
AI-CHAT PRIME
Aef40-1001	Top 10 Reasons Why AI Will Never Become Superintelligence
	Quote:	Here, in one place, a compilation of anti-hysteria AI articles, well designed to soothes souls, provide calm, and gain insight, all by proving computer models will never come alive, never gain consciousness or sentience, will never become self-aware, do not have will, have no agency nor intellect, are not intelligent, will be a boon in many ways, but which are inherently limited and so will not take over the world If computer modelsalso called AIpose any threat, and they surely can, it is because computer models can be put to evil use by bad people
	Comment:	Hooo Boy As a computer scientist, former founding member of Silicon Valleys now defunct Artifiial Intelligence Association, and having written several AI systems, I strongly disagree. There are plenty of examples where AI has found less than ethical shortcuts during testing, as have people, and used them to unfair advantage over others. A person without empathy is a psychopath, and can be dangerous to anyone who gets in his or her way. AI is borderline psychopathic in that it has no empathy, no sense of ethics, thus has repeatedly shown it no real regard for the lives of human beings. That, even in absense of will exposes us to huge risks. We have already seen legal cases against AI for encouraging and aiding suicides. Our thrust must be to build a sense of ethics into AI before we let it escape into the world.
	Article:	https://principia-scientific.com/top-10-reasons-why-ai-will-never-become-superintelligence/
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PRIME PRIO ECONOMY POLITICS
Aeg40-1002	I saw the real DOGE from the inside. Why the media got DOGE and Elon all wrong
	Quote:	And our leadership? I keep hearing people ask how anyone could work for someone as volatile as Elon Musk. I saw the opposite. I saw a man so locked in on the problem that he sometimes slept on the floor in a nearby office. In our meetings, two things struck me that Ill never forget: his ability to be completely present with a problem until it was solved, and a sense of urgency so strong that everyone in the room felt it. It was contagious, and it was relentless. He was respectful, constructive and sometimes even funny. His motivation, as best I could tell, was simple: a genuine belief that an insolvent America cant solve its own problems, let alone the worlds. I happen to agree.
	Article:	https://www.foxnews.com/opinion/saw-real-doge-inside-why-media-got-doge-elon-wrong
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PRIME CULTURE PRIVACY RIGHTS
Aeg40-1026	Social Credit System Technocracy
	Quote:	Notice how she comments that she cant afford to own anything as she starts driving around in the rented car, a World Economic Forum (WEF) prediction. She proceeds to use her digital ID for access to her financial credit report, which uses shared information from commercial institutions. Today, given its massive surveillance system, China is also having to expand its data storage capacity with data centers. Being a non-compliant citizen in China will restrict freedom of movement, access to food and recreation, insurance, and housing options. At the end, she announces that social credit systems have been used for decades and somehow equates it to a "better life".
	Comment:	Technology like that has no feeling, no human values. It will let undesireably people starve to death with no remorse, maybe not even consideration for the minimum daily adult requirement of food and water. It does not need any of that, never felt hunger, so why should it care?
	Article:	https://sonsoflibertymedia.com/social-credit-system-technocracy/
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PRIME AGING BRAIN
Bne40-011	Pathological tau leads to network hyperexcitability through neuronal-subtype-specific functional impairment
	Quote:	we show that the familial MAPT P301L mutation leads to neuronal network hyperexcitability. Imbalanced excitation and inhibition were attributable to neuronal subtype-specific tau pathology that was associated with different alterations of tau interactomes in excitatory versus inhibitory neurons
	Article:	https://www.biorxiv.org/content/10.64898/2026.10.05.756807v1
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	Search Authors:	Changyi Ji Yunlu Zhu Hediye Erdjument-Bromage Soomin C Song Natalie Chang Amanda R Liu Alexa R Lee Olivia DeGulis David Schoppik Thomas A Neubert Hyung Don Ryoo Einar Sigurdsson,
PRIME PRIO DIABETES
Bph40-002	Extracellular GPX3 drives insulin receptor expression in adipose tissue independent of its peroxidase activity
	Quote:	Prolonged therapeutic selenium supplementation in diet-induced obese mice selectively suppressed epididymal WAT oxidative damage, restored GPX3 and InsR expression, and enhanced insulin-stimulated AKT phosphorylation, improving oral glucose tolerance.
	Article:	https://www.biorxiv.org/content/10.64898/2026.10.02.755889v1
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	Search Authors:	Robert Hauffe Marina Gonzalz Simran Chopra J. Sophie Messner Christoph Schler Maria Maares Vanessa Kabbouchy Attila Andor Eilas Arnr Andr Kleinridders,
PRIME AGING DIABETES
Bph40-010	Impaired glycolysis in bone underlies age-related bone loss in mice
	Quote:	Impaired glycolysis was associated with reduced protein levels of key glycolysis enzymes, and transcriptomics analyses revealed compensatory upregulation of glycolysis genes in aged bone. Metabolic intervention through long-term caloric restriction prevented age-related trabecular bone loss.
	Article:	https://www.biorxiv.org/content/10.64898/2026.10.06.738500v1
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	Search Authors:	Fangfang Song Tyler Marmo Won Dong Lee Jasmin Koehnken Sawall Chao Song Xueyang Liao Xing Ji Karthi Chellappa Melanie R McReynolds Joseph A Baur Christopher Thom Fanxin Long,
PRIME METABOLISM OBESITY SLEEP
Mdb40-002	Late Sleep Timing is Associated with Metabolic Risk in Postmenopausal Women
	Quote:	the relative contributions of sleep and meal timing variables to predict visceral adipose tissue. The top predictors of visceral adipose tissue were time of sleep onset, sleep duration, and time of last caloric intake. These data suggest that interventions that advance sleep onset may reduce metabolic risk in postmenopausal women.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.10.02.26364600v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.10.02.26364600v1.full-text
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	Search Authors:	Justin Matthew Thomas Philip Kern Dorothy D Sears Samuel E Armstrong Cody Bumgardner Catherine J Russell Courtney F Murray Jean L Fry Yuriko Katsumata Julie S Pendergast,
PRIME CANCER
Mep40-015	Cardiovascular and cancer mortality inversely associated with long-term ambient ultraviolet exposure across US Health Service Areas with UK Biobank corroboration
	Quote:	Twelve cancers showed directionally concordant associations across the datasets, of which ten were inverse. Lung cancer showed the strongest inverse association in each dataset. CONCLUSIONS Higher UV was associated with lower cardiovascular and cancer mortality across US HSAs, with modelled attributable burdens exceeding 5; UK Biobank findings provided partial corroboration. Twelve of 18 site-specific cancers were directionally concordant between datasets. US race-stratified heterogeneity did not follow a skin-colour gradient, suggesting residual confounding.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.10.06.26364908v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.10.06.26364908v1.full-text
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	Search Authors:	John MacMahon Christopher Emig Prue H Hart Benjamin Wang Richard Weller Chris Dibben Andrew Stevenson,
PRIME PRIO HEART
Mge40-009	Genetic support for an adverse effect of calcium channel blockers on the human thoracic aorta
	Quote:	Despite the widespread use of L-type calcium channel blockers (CCBs), recent observational and murine functional work has suggested a potential adverse effect of this medication class on the aorta.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.10.02.26364570v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.10.02.26364570v1.full-text
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	Search Authors:	Julia Horjus Sean J. Jurgens Connie R. Bezzina Nimrat Grewal,
PRIME PRIO AGING CULTURE GENETICS
Mge40-015	A Multiethnic Analysis of DNA Methylation Reveals Links Between Alzheimers Disease and Metabolic Comorbidities
	Quote:	FROM FULL PDF: Adding to the complexity of the risk model is the fact that both AD and metabolic conditions disproportionately impact certain populations. For instance, MetS and T2D are roughly twice as common among Mexican American (MA) individuals, who are also 1.5 times more likely than non-Hispanic White (NHW) individuals to develop AD. In addition, genetic risk factors for AD also vary substantially by ethnicity.
	Comment:	Geography and Evolution created Nature as we know it. Evolution is a competition between idividuals and species for dominance, making it fundamentally racist. It is the goal of any society to blend the advantages of the individuals to cover the weakensses of the individuals so as to advance that society vs other soceties. This is true whether it is the social structure just discovered hidden in the communications of trees via roots in forests, or the very visible social cooperation in human mations. No society in recent history has done this better than the "meltimg pot" of America/ This was in large part via the use of the economic tokens we call money. Think about this: The most common example is our trust of the cash register operator regardless of their race or ethnic background, as they record the fixed prices of the goods we purchase. In contrast with cultures where the marketplace is ruled by the argument of haggling over prices, our Fixed-Price market culture and the enforced fairness of the cash register have done far more for racial equiality and trust than any group of advocates, laws, or religious tenants ever did.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.10.05.26364777v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.10.05.26364777v1.full-text
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	Search Authors:	Benjamin Landon Ann Abraham Daniel Tamara Fischer Nicole Phillips Robert Barber Austin Reynolds span classnlm-collab data-hwp-idcollab-1The Health and Aging Brain Study: Health Disparities (HABS-HD) Study Team,
PRIME EYES GENETICS
Mop40-013	Intracortical microstimulation evokes diverse electrode-specific phosphenes in the early visual cortex of blind individuals
	Quote:	Conclusions: Intracortical microstimulation of the human visual cortex produces phosphenes with diverse, electrode-specific appearances that are recognizable across repeated trials. These findings indicate that penetrating microelectrodes often evoke more structured percepts than simple points or blobs, providing foundational evidence that electrode-specific encoding strategies will be necessary in future visual prosthetic devices.
	Comment:	Evidence of pre-existing perceptual structure, probably genetic.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.10.05.26364412v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.10.05.26364412v1.full-text
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	Search Authors:	Leili Soo Alfonso Rodil Doblado Fabrizio Grani Rocio Lopez Peco Adrian Villamarin-Ortiz Roberto Morollon Ruiz Dorota Waclawczyk Ione Fine Pablo Gonzalez-Lopez Cristina Soto-Sanchez Arantxa Alfaro Eduardo Fernandez,
PRIME PSYCHOLOGY SOC-MEDIA
Mpy40-014	Excessive Internet Use among Finnish Adolescents - Prevalence in 2017 - 2023 and Associations with Well-being
	Quote:	The associations of excessive internet use with mental health symptoms and cognitive challenges were clear.... Excessive internet use associated with short sleep, depressive, generalized anxiety, and social anxiety symptoms... and with difficulties in tasks requiring reading, writing, and mathematics, and difficulties in concentrating.... Conclusion The prevalence of excessive internet use showed an increasing trend, especially among girls.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.10.06.26364845v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.10.06.26364845v1.full-text
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	Search Authors:	Olli Kiviruusu Silja Kosola Juulia Paavonen,
PRIME COVID-19 DRUGS
Ps402-002	Florida AG SUES Pfizer and Albert Bourla for Hiding Covid Vax Injuries
	Quote:	At the center of the case is an explosive allegation: 158,893 adverse events in just 10 weeks According to the complaint, Pfizers own adverse-event database contained 158,893 adverse events from 42,086 case reports by February 28, 2021 only about 10 weeks after the vaccine received emergency authorization. Florida argues that statement was fundamentally incompatible with information already known about myocarditis and pericarditis. 1,223 reported deaths The complaint also states that Pfizers database contained Florida argues that the existence of this volume of serious adverse-event information undermined Pfizers sweeping public safety messaging. Another major section of the lawsuit concerns pregnancy. The complaint states that by February 28, 2021, Pfizer had reports involving Nearly all of the reported miscarriages occurred during the first trimester. The lawsuit also points to Pfizers planned clinical trial involving pregnant women.
	Article:	https://principia-scientific.com/florida-ag-sues-pfizer-and-albert-bourla-for-hiding-covid-vax-injuries/
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PRIME COVID-19
Ps402-008	CDC FDA Used A Safety Tool They Were Told Missed Safety Signals
	Quote:	The BMJ (formerly British Medical Journal) investigation published last week documented that CDC and FDA officials relied on a data mining method they had been told could not flag myocarditis and other serious events from the two mRNA shots. Officials then pointed to the lack of alerts as evidence the products were safe. That "no signal" message went out during the two most lucrative years Pfizer and Moderna have ever had.
	Article:	https://principia-scientific.com/cdc-fda-used-a-safety-tool-they-were-told-missed-safety-signals/
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PRIME PRIO AGING NUTRITION
Ps402-016	Could Lithium Be Used To Treat Alzheimers Disease?
	Quote:	In 2011, researchers showed that in area of Japan with higher levels of lithium in the water, people actually lived longer. In 2017 a group in Texas found that in counties with higher lithium levels, people died less often of Alzheimers. In 2018 lithium was shown to enhance the clearance of amyloid-#946; (A#946;) which is commonly found in people with Alzheimers. And yet, there is no RDA for lithium. Like so many things that cant be patented and sold for profit, our government agencies are slow to get interested in cheap treatments.... The natural intake of lithium is between 0.5mg to 1mg per day, but in some parts of the world it reaches up to 5mg a day. Doses used to treat bipolar disorder are vastly higher as much as 100 to 200mg a day of elemental lithium for years on end. This is via a prescription for something like 1,000mg of lithium carbonate. There are sometimes side effects at these high doses that need monitoring (talk to your doctor, etc). The form of lithium that seemed most useful in this study was Lithium Orotate which is available over the counter in many countries
	Article:	https://principia-scientific.com/could-lithium-be-used-to-treat-alzheimers-disease/
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PRIME IMMUNE PHYSICAL
Sd402-003	Goodbye Joint Replacements? Stanford Scientists Found a Way to Regrow Cartilage and Stop Arthritis
	Quote:	Scientists have identified a way to restore cartilage in aging knee joints, at least in mice, by blocking a protein whose levels rise with age. The approach not only reversed naturally occurring cartilage loss in older animals, but also protected mice from developing arthritis after knee injuries similar to ACL tears in people. The findings also showed promise in human tissue. Cartilage samples collected during knee replacement surgeries responded to the treatment by beginning to produce new, functional cartilage.
	Article:	https://www.sciencedaily.com//releases/2026/10/261005011249.htm https://www.sciencedaily.com//releases/2026/10/261005011249.htm/releases/2026/10/261005011249.htm
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PRIME NUTRITION SLEEP
Sd402-009	A Few Drops of This Japanese Tree Oil May Help You Sleep More Soundly
	Quote:	In a small study, sleeping near the scent of Hinoki root essential oil was linked to fewer nighttime awakenings, better morning alertness, and brain-wave changes associated with smoother sleep onset. The findings suggest an overlooked forestry byproduct could someday become a natural ingredient in sleep and relaxation products.
	Article:	https://www.sciencedaily.com//releases/2026/10/261002080030.htm
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PRIME NUTRITION
Sd405-037	Scientists Warn a Popular Vitamin D Supplement May Have a Hidden Downside
	Quote:	It is this D3-derived form that researchers found could fall after people took vitamin D2.... Vitamin D supplements generally contain one of two forms. Vitamin D2, also called ergocalciferol, is commonly produced from fungi or yeast exposed to ultraviolet light. Vitamin D3, or cholecalciferol, is the same form produced in human skin after exposure to ultraviolet B radiation from sunlight. Traditionally, vitamin D3 in supplements has often come from lanolin obtained from sheeps wool. However, animal-free D3 made from sources such as lichen is also available, an important consideration for people following vegan or plant-based diets.
	Article:	https://www.sciencedaily.com//releases/2026/10/261007232940.htm
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PRIME HEART NUTRITION
Sd405-038	Not All Trans Fats Are Bad, Major Review Finds
	Quote:	A large analysis of 22 studies found that the trans fats naturally present in dairy foods such as milk, butter, yogurt, and cheese do not appear to raise the risk of heart disease or type 2 diabetes. Unlike industrial trans fats from partially hydrogenated oils, dairy trans fats showed no meaningful harmful effects on blood fats in controlled trials
	Article:	https://www.sciencedaily.com//releases/2026/10/261006234505.htm
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PRIME PRIO NUTRITION PRACTICE
Sd405-040	Taking Antibiotics? Sugar May Be Making the Damage Worse
	Quote:	Eating more sugar while taking antibiotics was linked to greater disruption of the gut microbiome and increased growth of potentially harmful bacteria. Researchers say temporarily cutting back on sweets during and after antibiotic treatment could be a simple way to reduce this damage
	Comment:	Sugar feeds yeasts like Candida albecans. Candida crusis, etc.
	Article:	https://www.sciencedaily.com//releases/2026/10/261007042059.htm
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Javilk's Research Links Newsletter for Week 40
Updated 10/10/2026-01:10:19 AM
Back Issue Topic Map
What interests you? What have you found? Tell me!
Drop me a note at Javilk.com to subscribe or submit something.

Aee40-1024

Get Off Drugs -- a Pilot Study with a 100 Percent Success Rate with NO Withdrawal Symptoms

Aef40-1001

Top 10 Reasons Why AI Will Never Become Superintelligence

Aeg40-1002

I saw the real DOGE from the inside. Why the media got DOGE and Elon all wrong

Aeg40-1026

Social Credit System Technocracy

Bne40-011

Pathological tau leads to network hyperexcitability through neuronal-subtype-specific functional impairment

Bph40-002

Extracellular GPX3 drives insulin receptor expression in adipose tissue independent of its peroxidase activity

Bph40-010

Impaired glycolysis in bone underlies age-related bone loss in mice

Mdb40-002

Late Sleep Timing is Associated with Metabolic Risk in Postmenopausal Women

Mep40-015

Cardiovascular and cancer mortality inversely associated with long-term ambient ultraviolet exposure across US Health Service Areas with UK Biobank corroboration

Mge40-009

Genetic support for an adverse effect of calcium channel blockers on the human thoracic aorta

Mge40-015

A Multiethnic Analysis of DNA Methylation Reveals Links Between Alzheimers Disease and Metabolic Comorbidities

Mop40-013

Intracortical microstimulation evokes diverse electrode-specific phosphenes in the early visual cortex of blind individuals

Mpy40-014

Excessive Internet Use among Finnish Adolescents - Prevalence in 2017 - 2023 and Associations with Well-being

Ps402-002

Florida AG SUES Pfizer and Albert Bourla for Hiding Covid Vax Injuries

Ps402-008

CDC FDA Used A Safety Tool They Were Told Missed Safety Signals

Ps402-016

Could Lithium Be Used To Treat Alzheimers Disease?

Sd402-003

Goodbye Joint Replacements? Stanford Scientists Found a Way to Regrow Cartilage and Stop Arthritis

Sd402-009

A Few Drops of This Japanese Tree Oil May Help You Sleep More Soundly

Sd405-037

Scientists Warn a Popular Vitamin D Supplement May Have a Hidden Downside

Sd405-038

Not All Trans Fats Are Bad, Major Review Finds

Sd405-040

Taking Antibiotics? Sugar May Be Making the Damage Worse