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Aeg40-1002

I saw the real DOGE from the inside. Why the media got DOGE and Elon all wrong

Quote: And our leadership? I keep hearing people ask how anyone could work for someone as volatile as Elon Musk. I saw the opposite. I saw a man so locked in on the problem that he sometimes slept on the floor in a nearby office. In our meetings, two things struck me that Ill never forget: his ability to be completely present with a problem until it was solved, and a sense of urgency so strong that everyone in the room felt it. It was contagious, and it was relentless. He was respectful, constructive and sometimes even funny. His motivation, as best I could tell, was simple: a genuine belief that an insolvent America cant solve its own problems, let alone the worlds. I happen to agree.
Article: https://www.foxnews.com/opinion/saw-real-doge-inside-why-media-got-doge-elon-wrong
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    PRIME    PRIO    DIABETES   

Bph40-002

Extracellular GPX3 drives insulin receptor expression in adipose tissue independent of its peroxidase activity

Quote: Prolonged therapeutic selenium supplementation in diet-induced obese mice selectively suppressed epididymal WAT oxidative damage, restored GPX3 and InsR expression, and enhanced insulin-stimulated AKT phosphorylation, improving oral glucose tolerance.
Article: https://www.biorxiv.org/content/10.64898/2026.10.02.755889v1
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Search Authors: Robert Hauffe Marina Gonzalz Simran Chopra J. Sophie Messner Christoph Schler Maria Maares Vanessa Kabbouchy Attila Andor Eilas Arnr Andr Kleinridders, 
    PRIME    PRIO    HEART   

Mge40-009

Genetic support for an adverse effect of calcium channel blockers on the human thoracic aorta

Quote: Despite the widespread use of L-type calcium channel blockers (CCBs), recent observational and murine functional work has suggested a potential adverse effect of this medication class on the aorta.
Abstract: https://www.medrxiv.org/content/10.64898/2026.10.02.26364570v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.10.02.26364570v1.full-text
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Search Authors: Julia Horjus Sean J. Jurgens Connie R. Bezzina Nimrat Grewal, 
    PRIME    PRIO    AGING    CULTURE    GENETICS   

Mge40-015

A Multiethnic Analysis of DNA Methylation Reveals Links Between Alzheimers Disease and Metabolic Comorbidities

Quote: FROM FULL PDF: Adding to the complexity of the risk model is the fact that both AD and metabolic conditions disproportionately impact certain populations. For instance, MetS and T2D are roughly twice as common among Mexican American (MA) individuals, who are also 1.5 times more likely than non-Hispanic White (NHW) individuals to develop AD. In addition, genetic risk factors for AD also vary substantially by ethnicity.
Comment: Geography and Evolution created Nature as we know it. Evolution is a competition between idividuals and species for dominance, making it fundamentally racist. It is the goal of any society to blend the advantages of the individuals to cover the weakensses of the individuals so as to advance that society vs other soceties. This is true whether it is the social structure just discovered hidden in the communications of trees via roots in forests, or the very visible social cooperation in human mations. No society in recent history has done this better than the "meltimg pot" of America/ This was in large part via the use of the economic tokens we call money. Think about this: The most common example is our trust of the cash register operator regardless of their race or ethnic background, as they record the fixed prices of the goods we purchase. In contrast with cultures where the marketplace is ruled by the argument of haggling over prices, our Fixed-Price market culture and the enforced fairness of the cash register have done far more for racial equiality and trust than any group of advocates, laws, or religious tenants ever did.
Abstract: https://www.medrxiv.org/content/10.64898/2026.10.05.26364777v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.10.05.26364777v1.full-text
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Search Authors: Benjamin Landon Ann Abraham Daniel Tamara Fischer Nicole Phillips Robert Barber Austin Reynolds span classnlm-collab data-hwp-idcollab-1The Health and Aging Brain Study: Health Disparities (HABS-HD) Study Team, 
    PRIME    PRIO    AGING    NUTRITION   

Ps402-016

Could Lithium Be Used To Treat Alzheimers Disease?

Quote: In 2011, researchers showed that in area of Japan with higher levels of lithium in the water, people actually lived longer. In 2017 a group in Texas found that in counties with higher lithium levels, people died less often of Alzheimers. In 2018 lithium was shown to enhance the clearance of amyloid-#946; (A#946;) which is commonly found in people with Alzheimers. And yet, there is no RDA for lithium. Like so many things that cant be patented and sold for profit, our government agencies are slow to get interested in cheap treatments....

The natural intake of lithium is between 0.5mg to 1mg per day, but in some parts of the world it reaches up to 5mg a day. Doses used to treat bipolar disorder are vastly higher as much as 100 to 200mg a day of elemental lithium for years on end. This is via a prescription for something like 1,000mg of lithium carbonate. There are sometimes side effects at these high doses that need monitoring (talk to your doctor, etc). The form of lithium that seemed most useful in this study was Lithium Orotate which is available over the counter in many countries

Article: https://principia-scientific.com/could-lithium-be-used-to-treat-alzheimers-disease/
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    PRIME    PRIO    NUTRITION    PRACTICE   

Sd405-040

Taking Antibiotics? Sugar May Be Making the Damage Worse

Quote: Eating more sugar while taking antibiotics was linked to greater disruption of the gut microbiome and increased growth of potentially harmful bacteria. Researchers say temporarily cutting back on sweets during and after antibiotic treatment could be a simple way to reduce this damage
Comment: Sugar feeds yeasts like Candida albecans. Candida crusis, etc.
Article: https://www.sciencedaily.com//releases/2026/10/261007042059.htm
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  Javilk's Research Links Newsletter for Week 40
Updated 10/10/2026-01:10:19 AM
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