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    IMMUNE    REPRODUCTION   

Mob40-013

Pyelonephritis is associated with persistent alterations in immune-stromal and vascular programs in the human placenta

Quote: Histopathology further demonstrated increased lesions associated with maternal vascular malperfusion and perivillous fibrin deposition. Together, these findings identify the villous immune-stromal-vascular microenvironment as a persistent site of placental remodeling following maternal infection and suggest that clinical recovery from maternal illness may not coincide with normalization of placental biology.
Abstract: https://www.medrxiv.org/content/10.64898/2026.10.05.26364820v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.10.05.26364820v1.full-text
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Search Authors: Christine Blauvelt Nida Ozarslan Stephanie M Tsoi Olena Trush Chloe Taylor Sirirak Buarpung Megan Chidboy Jeanine S. Esteban Amayrani Morales Corina A Mong Neela Rahseparian Cynthia Gasper Joshua F Robinson Elizabeth E Crouch Stephanie L Gaw, 
    PRIME    IMMUNE    PHYSICAL   

Sd402-003

Goodbye Joint Replacements? Stanford Scientists Found a Way to Regrow Cartilage and Stop Arthritis

Quote: Scientists have identified a way to restore cartilage in aging knee joints, at least in mice, by blocking a protein whose levels rise with age. The approach not only reversed naturally occurring cartilage loss in older animals, but also protected mice from developing arthritis after knee injuries similar to ACL tears in people. The findings also showed promise in human tissue. Cartilage samples collected during knee replacement surgeries responded to the treatment by beginning to produce new, functional cartilage.
Article: https://www.sciencedaily.com//releases/2026/10/261005011249.htm https://www.sciencedaily.com//releases/2026/10/261005011249.htm/releases/2026/10/261005011249.htm
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    AGING    BRAIN    IMMUNE   

Sd405-015

Drug Target Could Block Brain Inflammation Linked to Alzheimers and Parkinsons

Quote: The team found that P2X7 receptors promote the release of cytokines, proteins that help regulate inflammatory responses. When the researchers used a specific antagonist to block the receptor, the inflammatory response in human brain tissue dropped significantly.
Article: https://www.sciencedaily.com//releases/2026/10/261005071515.htm
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  Javilk's Research Links Newsletter for Week 40
Updated 10/10/2026-01:10:19 AM
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