| Research Topics: |
| INDEX |
| AI-chat 3 |
| PRIME 25 |
| PRIO 3 |
| aging 7 |
| brain 3 |
| cancer 2 |
| censorship 2 |
| climate 2 |
| cognition 6 |
| computers 1 |
| covid-19 4 |
| crime 2 |
| culture 5 |
| diabetes 4 |
| drugs 3 |
| economy 3 |
| energy 2 |
| eyes 1 |
| genetics 1 |
| health 1 |
| heart 1 |
| immune 3 |
| metabolism 2 |
| microbiome 1 |
| nutrition 4 |
| obesity 4 |
| pain 1 |
| physical 3 |
| politics 7 |
| pollution 3 |
| population 4 |
| practice 4 |
| psychology 2 |
| quantum 2 |
| radiation 2 |
| reproduction 2 |
| rights 2 |
| sleep 1 |
| soc-media |
| unk |
| vaccine 2 |
| war-cyber 2 |
|
Scanned: 2562 Evaluated: 172 Selected: 51 Back Issue Map |
| PRIME METABOLISM | ||||||||
Bge41-007 | Single-cell variant landscape of the human mitochondrial genome reveals cell type-specific functions and disease mechanisms | |||||||
| Quote: | Mitochondrial DNA (mtDNA) heteroplasmy is a significant source of cellular genetic diversity and can cause disease yet its distribution and functional importance across different human cell types are poorly understood. Here we present scMOCHA (Single-Cell Mitochondrial Omics for Cellular Heteroplasmy Analysis), a scalable computational framework that resolves highconfidence, single-cell resolution mtDNA heteroplasmy directly from standard single-cell RNA sequencing (scRNA-seq) data. Using this tool to interrogate publicly available scRNA-seq datasets from human peripheral blood mononuclear cells (PBMC) and bone marrow (BM) uncovered the single-cell landscape of mtDNA single-nucleotide variants (SNVs) and heteroplasmy across ages in human hematopoietic cell types. | |||||||
| Article: | https://www.biorxiv.org/content/10.64898/2026.10.11.758340v1 | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Chunjie Liu Ting Peng Zimu Cen Peiran Lu Prasanth Potluri Po Hu Shiping Zhang Marie T Lott Gabrielle Widjaja Douglas C Wallace Yi Xing Liming Pei, | |||||||
| PRIME PRIO METABOLISM NUTRITION | ||||||||
Ps410-004 | New Study Links Falling Body Temperature to Chronic Illness | |||||||
| Quote: | The same population, while it held 98.6F, had the healthiest hearts ever recorded. Now that their temperature is falling, Cormier calls them one of the strongest available tests of his hypothesis: if temperature tracks metabolic health, their metabolic disease should rise as their temperature drops. The paper lays out the data. | |||||||
| Comment: | Wilsons Syndrome. Lower body temperature results in more arthritis, allergies, and other poor maintenance effects. WHt is the cause? Maybe, just Maybe, it is our need to do more thinking and less reacting in our safe and comfortable society. I think far more deeply at 97.5, than at 98.6. By 98.0, I am an outgoing active person; but NOT the deep analyst anymore. There are mental means of raising or lowering ones body temperature as needed for the tasks at hand, and some of that is just natural, diet can also play a role. See the coldbody page. | |||||||
| Article: | https://principia-scientific.com/new-study-links-falling-body-temperature-to-chronic-illness/ | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
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Javilk's Research Links Newsletter for Week 41 Updated 10/17/2026-02:05:55 AM Back Issue Topic Map What interests you? What have you found? Tell me! Drop me a note at Javilk.com to subscribe or submit something. |