Research
Topics:
INDEX
AI-chat 3
PRIME 33
PRIO 3
aging 9
brain 14
brainwave 1
cancer 12
climate 4
cognition 3
covid-19 1
crime 2
culture 2
dental 2
diabetes 4
drugs 1
economy 4
election 3
energy 2
genetics 9
gut 1
heart 5
immune 6
law 1
metabolism 1
misc 2
nutrition 7
obesity 1
politics 5
pollution 4
practice 1
psychology 3
quantum 2
reproduction 2
rights 1
sleep 1
space 2
tech 4
vaccine 2
virus 3
war-confl
war-cyber 1
 
Scanned: 3392
Evaluated: 268
Selected: 71

 
Back Issue Map
    PRIME    AGING    CANCER    GENETICS   

Bcb44-009

Polycomb Marked Promoter Methylation Gains in Aging and Cancer are Independent of Replication

Quote: Together, these findings show that epigenetic trajectories during early tumor development, are rooted in baseline, age-dependent drivers of epigenetic alterations, and that oncogenic signaling acts primarily by selecting and expanding clones bearing pre-existing, age-associated epigenetic drift rather than instructing new methylation. Our findings have implications for how promoter methylation is interpreted as a cancer biomarker and for identifying upstream aging-associated processes as targets for early intervention.
Article: https://www.biorxiv.org/content/10.64898/2026.10.30.763235v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Hari Easwaran Sara-Jayne Thursby Nibedita Patel Zhicheng Jin Jacob Blum Shilpa Bisht Yong Tao Yuba Bhandari Daniel Petkovich Hisashi Ro Lijing Yang Jeff (Tza-Huei) R Wang Thomas Pisanic span classnlm-suffixII Stephen Bruce Baylin, 
    GENETICS   

Bge44-011

The genetic architecture of human DNA methylome variation

Article: https://www.biorxiv.org/content/10.64898/2026.11.01.763325v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Tianjie Liu Juan F. Macias-Velasco Xiaoyu Zhuo Jiadong Lin David Porubsky Wenjin Zhang Daofeng Li Chad Tomlinson Edward A. Belter Zheng Dong Shihua Dong span classnlm-collab data-hwp-idcollab-1Human Pangenome Reference Consortium Evan Eichler Ting Wang, 
    PRIME    GENETICS   

Bgn44-017

NanoPAMDA enables rapid PAM characterization of metagenome-derived Cas9 effectors

Quote: CRISPR-Cas9 orthologs remain functionally underexplored despite the rapidly growing scale of publicly available metagenomic sequencing data. Here, we applied a multi-stage computational discovery pipeline to two independent sources of metagenomic sequence data, a multi-biome collection of 660,185 metagenome-assembled genomes spanning 17 public catalogs, and raw sequencing reads from human microbiome studies assembled de novo, to identify novel Cas9 orthologs.
Article: https://www.biorxiv.org/content/10.64898/2026.11.04.764188v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Ibrahim Genel Ceren Suren Ibrahim Cagri Kurt, 
    CANCER    GENETICS   

Bgn44-018

Epigenetic reprogramming by promoter hypomethylation is linked to aberrant gene expression and transcriptomic plasticity in colorectal cancer

Article: https://www.biorxiv.org/content/10.64898/2026.11.04.763625v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Lus Nunes Ina A. Eilertsen Rita Pinto Hege M. Vedeld Ingrid M. Bolstad Usman Saeed Ole H. Sjo Sheraz Yaqub Arild Nesbakken Kushtrim Kryeziu Guro E. Lind Ragnhild A. Lothe Anita Sveen, 
    GENETICS   

Bgn44-019

Highly prevalent cargo genes of F plasmids harbored in pathogenic Escherichia coli

Article: https://www.biorxiv.org/content/10.64898/2026.11.04.764203v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Sara Guirao-Rico Saskia Camille Flament-Simon Cristina Madrid Carlos Balsalobre Mario Huttener Jesus Eulogio Blanco Jorge Blanco Julio Rozas Antonio Juarez, 
    GENETICS    IMMUNE    METABOLISM   

Bmo44-007

A new tool for quantifying mitochondrial RNA processing intermediates reveals increased levels of immature mRNA species under oxidative stress

Article: https://www.biorxiv.org/content/10.64898/2026.10.30.763231v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Ulas Ozkurede Shreya Rajhans Federica Accornero Julia C Liu, 
    GENETICS   

Bmo44-008

The DNA demethylase TET1 recognises chromatin via nucleosome engagement of its N-terminal region

Article: https://www.biorxiv.org/content/10.64898/2026.10.31.763349v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Franck Martin Hayden Burdett Melody Matelot Chloe Ngon Baroung Beatrice Alexander-Howden Marcus D. Wilson Elisa Bergamin Raphael Pantier, 
    GENETICS    VIRUS   

Bmo44-011

XRN1-dependent RNA homeostasis regulates hepatitis D virus

Article: https://www.biorxiv.org/content/10.64898/2026.11.01.763535v1
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 
Search Authors: Senko Tsukuda Medhi Boutasbih Peter A.C. Wing Aleksandr Fedorov Xiaxuan Zhu Jan Rehwinkel Peter Balfe Jane A. McKeating, 
    GENETICS   

Sd443-011

All 5 Genetic Letters of DNA and RNA Discovered in a 4.5-billion-year-old Asteroid

Quote: Scientists have discovered all five essential nucleobases used in DNA and RNA in pristine samples from asteroid Ryugu, revealing that key ingredients for life existed in space billions of years ago. The remarkable finding adds to growing evidence from other asteroids and meteorites that these molecules were widespread throughout the early Solar System.
Article: https://www.sciencedaily.com//releases/2026/11/261102075903.htm
Search Similar: Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho 

  Javilk's Research Links Newsletter for Week 44
Updated 11/06/2026-10:26:45 PM
Back Issue Topic Map
What interests you? What have you found? Tell me!
Drop me a note at Javilk.com to subscribe or submit something.